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Published in: Lung 1/2010

01-02-2010

Cheyne-Stokes Respiration in Patients with Heart Failure

Authors: Laila AlDabal, Ahmed S. BaHammam

Published in: Lung | Issue 1/2010

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Abstract

Cheyne-Stokes respiration (CSR) is a form of central sleep-disordered breathing (SDB) in which there are cyclical fluctuations in breathing that lead to periods of central apneas/hypopnea, which alternate with periods of hyperpnea. The crescendo–decrescendo pattern of respiration in CSR is a compensation for the changing levels of blood oxygen and carbon dioxide. Severe congestive heart failure seems to be the most important risk factor for the development of CSR. A number of pathophysiologic changes, such as sleep disruption, arousals, hypoxemia-reoxygenation, hypercapnia/hypocapnia, and changes in intrathoracic pressure have harmful effects on the cardiovascular system, and the presence of CSR is associated with increased mortality and morbidity in subjects with variable degrees of heart failure. The management of CSR involves optimal control of underlying heart failure, oxygen therapy, and positive airway pressure support. In this review, we initially define and describe the epidemiology of central sleep apnea (CSA) and CSR, its pathogenesis, clinical presentation, diagnostic methods, and then discuss the recent developments in the management in patients with heart failure.
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Metadata
Title
Cheyne-Stokes Respiration in Patients with Heart Failure
Authors
Laila AlDabal
Ahmed S. BaHammam
Publication date
01-02-2010
Publisher
Springer-Verlag
Published in
Lung / Issue 1/2010
Print ISSN: 0341-2040
Electronic ISSN: 1432-1750
DOI
https://doi.org/10.1007/s00408-009-9200-4

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