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Published in: European Archives of Psychiatry and Clinical Neuroscience 1/2011

01-02-2011 | Original Paper

Combining the categorical and the dimensional perspective in a diagnostic map of psychotic disorders

Authors: Damian Läge, Samy Egli, Michael Riedel, Anton Strauss, Hans-Jürgen Möller

Published in: European Archives of Psychiatry and Clinical Neuroscience | Issue 1/2011

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Abstract

We introduce a diagnostic map that was calculated by robust non-metric multidimensional scaling based on AMDP symptom profiles of patients with schizophrenic and affective disorders to demonstrate a possibility to combine the categorical and the dimensional perspective at the same time. In the diagnostic map, a manic, a depressive, and a non-affective cluster clearly emerged. At the same time, the mania dimension (r = 0.82), the depression dimension (r = 0.68), and the apathy dimension (r = 0.74) showed high multiple regression values in the map. We found substantial overlaps of the diagnostic groups with regard to the affective spectrum but irrespective of the ICD-10 classification. Within this sample, we found the association and quality of mood symptoms to be a structuring principle in a diagnostic map. We demonstrate that this approach represents a promising way of combining the categorical and the dimensional perspective. As a practical implementation of these findings, a multidimensional diagnostic map could serve as an automated diagnostic tool based on psychopathological symptom profiles.
Literature
1.
go back to reference Allardyce J, Gaebel W, Zielasek J, van Os J (2007) Deconstructing psychosis conference February 2006: the validity of schizophrenia and alternative approaches to the classification of psychosis. Schizophr Bull 33(4):863–867CrossRefPubMed Allardyce J, Gaebel W, Zielasek J, van Os J (2007) Deconstructing psychosis conference February 2006: the validity of schizophrenia and alternative approaches to the classification of psychosis. Schizophr Bull 33(4):863–867CrossRefPubMed
2.
go back to reference Allardyce J, Suppes T, Van Os J (2007) Dimensions and the psychosis phenotype. Int J Methods Psychiatr Res 16(1):34–40CrossRef Allardyce J, Suppes T, Van Os J (2007) Dimensions and the psychosis phenotype. Int J Methods Psychiatr Res 16(1):34–40CrossRef
3.
go back to reference Arbeitsgemeinschaft für Methodik und Dokumentation in der Psychiatrie (1981) Das AMDP-system. Manual zur Dokumentation psychiatrischer Befunde. Springer, Berlin Arbeitsgemeinschaft für Methodik und Dokumentation in der Psychiatrie (1981) Das AMDP-system. Manual zur Dokumentation psychiatrischer Befunde. Springer, Berlin
4.
go back to reference Backhaus K, Erichson B, Plinke W, Weiber R (2006) Multivariate Analysemethoden, 11th edn. Springer, Berlin Backhaus K, Erichson B, Plinke W, Weiber R (2006) Multivariate Analysemethoden, 11th edn. Springer, Berlin
5.
go back to reference Baumann U, Stieglitz RD (1997) Das AMDP-system: ein psychologischer test? In: Haug H-J, Stieglitz RD (eds) Das AMDP-system in der klinischen Anwendung und Forschung. Hogrefe, Göttingen, pp 30–45 Baumann U, Stieglitz RD (1997) Das AMDP-system: ein psychologischer test? In: Haug H-J, Stieglitz RD (eds) Das AMDP-system in der klinischen Anwendung und Forschung. Hogrefe, Göttingen, pp 30–45
6.
go back to reference Blashfield RK (1990) Comorbidity and classification. In: Maser JD, Cloninger CR (eds) Comorbidity of mood and anxiety disorders. American Psychiatric Press, Washington, pp 61–82 Blashfield RK (1990) Comorbidity and classification. In: Maser JD, Cloninger CR (eds) Comorbidity of mood and anxiety disorders. American Psychiatric Press, Washington, pp 61–82
7.
go back to reference Boks MP, Leask S, Vermunt JK, Kahn RS (2007) The structure of psychosis revisited: the role of mood symptoms. Schizophr Res 93(1–3):178–185CrossRefPubMed Boks MP, Leask S, Vermunt JK, Kahn RS (2007) The structure of psychosis revisited: the role of mood symptoms. Schizophr Res 93(1–3):178–185CrossRefPubMed
8.
go back to reference Borg I, Groenen P (2005) Modern multidimensional scaling—theory and applications, 2nd edn. Springer, New York Borg I, Groenen P (2005) Modern multidimensional scaling—theory and applications, 2nd edn. Springer, New York
9.
go back to reference Brown TA, Barlow DH (2005) Dimensional versus categorical classification of mental disorders in the fifth edition of the diagnostic and statistical manual of mental disorders and beyond: comment on the special section. J Abnorm Psychol 114(4):551–556CrossRefPubMed Brown TA, Barlow DH (2005) Dimensional versus categorical classification of mental disorders in the fifth edition of the diagnostic and statistical manual of mental disorders and beyond: comment on the special section. J Abnorm Psychol 114(4):551–556CrossRefPubMed
10.
go back to reference Craddock N, Owen MJ (2007) Rethinking psychosis: the disadvantages of a dichotomous classification now outweigh the advantages. World Psychiatry 6(2):20–27 Craddock N, Owen MJ (2007) Rethinking psychosis: the disadvantages of a dichotomous classification now outweigh the advantages. World Psychiatry 6(2):20–27
11.
go back to reference Cuesta MJ, Peralta V (2001) Integrating psychopathological dimensions in functional psychoses: a hierarchical approach. Schizophr Res 52(3):215–229CrossRefPubMed Cuesta MJ, Peralta V (2001) Integrating psychopathological dimensions in functional psychoses: a hierarchical approach. Schizophr Res 52(3):215–229CrossRefPubMed
12.
go back to reference Cuesta MJ, Peralta V, Zarzuela A (2000) Reappraising insight in psychosis. Multi-scale longitudinal study. Br J Psychiatry 177:233–240CrossRefPubMed Cuesta MJ, Peralta V, Zarzuela A (2000) Reappraising insight in psychosis. Multi-scale longitudinal study. Br J Psychiatry 177:233–240CrossRefPubMed
13.
go back to reference De Boeck P, Wilson M, Acton GS (2005) A conceptual and psychometric framework for distinguishing categories and dimensions. Psychol Rev 112(1):129–158CrossRefPubMed De Boeck P, Wilson M, Acton GS (2005) A conceptual and psychometric framework for distinguishing categories and dimensions. Psychol Rev 112(1):129–158CrossRefPubMed
14.
go back to reference Egli S, Riedel M, Möller HJ, Strauss A, Läge D (2009) Creating a map of psychiatric patients based on psychopathological symptom profiles. Eur Arch Psychiatry Clin Neurosci 259:164–171CrossRefPubMed Egli S, Riedel M, Möller HJ, Strauss A, Läge D (2009) Creating a map of psychiatric patients based on psychopathological symptom profiles. Eur Arch Psychiatry Clin Neurosci 259:164–171CrossRefPubMed
15.
go back to reference Fleiss JL, Spitzer RL, Cohen J, Endicott J (1972) Three computer diagnosis methods compared. Arch Gen Psychiat 27:643–649PubMed Fleiss JL, Spitzer RL, Cohen J, Endicott J (1972) Three computer diagnosis methods compared. Arch Gen Psychiat 27:643–649PubMed
16.
go back to reference Guy GW, Ban TA (1982) The AMDP system. Manual for the assessment and documentation of psychopathology. Springer, Berlin Guy GW, Ban TA (1982) The AMDP system. Manual for the assessment and documentation of psychopathology. Springer, Berlin
17.
go back to reference Hirschfeld R, Spitzer RL, Miller RG (1974) Computer diagnosis in psychiatry: a Bayes approach. J Nerv Ment Dis 158(6):399–407CrossRefPubMed Hirschfeld R, Spitzer RL, Miller RG (1974) Computer diagnosis in psychiatry: a Bayes approach. J Nerv Ment Dis 158(6):399–407CrossRefPubMed
19.
go back to reference Jablensky A (2005) Categories, dimensions and prototypes: critical issues for psychiatric classification. Psychopathology 38(4):201–205CrossRefPubMed Jablensky A (2005) Categories, dimensions and prototypes: critical issues for psychiatric classification. Psychopathology 38(4):201–205CrossRefPubMed
20.
go back to reference Jäger M, Bottlender R, Strauss A, Möller HJ (2004) Fifteen-year follow-up of ICD-10 schizoaffective disorders compared with schizophrenia and affective disorders. Acta Psychiatr Scand 109(1):30–37CrossRefPubMed Jäger M, Bottlender R, Strauss A, Möller HJ (2004) Fifteen-year follow-up of ICD-10 schizoaffective disorders compared with schizophrenia and affective disorders. Acta Psychiatr Scand 109(1):30–37CrossRefPubMed
21.
go back to reference Kendell R, Jablensky A (2003) Distinguishing between the validity and utility of psychiatric diagnoses. Am J Psychiatry 160(1):4–12CrossRefPubMed Kendell R, Jablensky A (2003) Distinguishing between the validity and utility of psychiatric diagnoses. Am J Psychiatry 160(1):4–12CrossRefPubMed
22.
go back to reference Kraemer HC (2007) DSM categories and dimensions in clinical and research contexts. Int J Methods Psychiatr Res 16(1):8–15CrossRef Kraemer HC (2007) DSM categories and dimensions in clinical and research contexts. Int J Methods Psychiatr Res 16(1):8–15CrossRef
23.
go back to reference Kupfer DJ (2005) Dimensional models for research and diagnosis: a current dilemma. J Abnorm Psychol 114(4):557–559CrossRefPubMed Kupfer DJ (2005) Dimensional models for research and diagnosis: a current dilemma. J Abnorm Psychol 114(4):557–559CrossRefPubMed
24.
go back to reference Läge D, Daub S, Bosia L, Jäger C, Ryf S (2005) Die Behandlung ausreißerbehafteter Datensätze in der Nonmetrischen Multidimensionalen Skalierung—Relevanz, Problemanalyse und Lösungsvorschlag. Forschungsberichte aus der Angewandten Kognitionspsychologie: Universität Zürich, Psychologisches Institut. Report No. 21 Läge D, Daub S, Bosia L, Jäger C, Ryf S (2005) Die Behandlung ausreißerbehafteter Datensätze in der Nonmetrischen Multidimensionalen Skalierung—Relevanz, Problemanalyse und Lösungsvorschlag. Forschungsberichte aus der Angewandten Kognitionspsychologie: Universität Zürich, Psychologisches Institut. Report No. 21
25.
go back to reference Lastra I, Vazquez-Barquero JL, Herrera Castanedo S, Cuesta MJ, Vazquez-Bourgon ME, Dunn G (2000) The classification of first episode schizophrenia: a cluster-analytical approach. Acta Psychiatr Scand 102(1):26–31CrossRefPubMed Lastra I, Vazquez-Barquero JL, Herrera Castanedo S, Cuesta MJ, Vazquez-Bourgon ME, Dunn G (2000) The classification of first episode schizophrenia: a cluster-analytical approach. Acta Psychiatr Scand 102(1):26–31CrossRefPubMed
26.
go back to reference Manton KG, Korten A, Woodbury MA, Anker M, Jablensky A (1994) Symptom profiles of psychiatric disorders based on graded disease classes: an illustration using data from the WHO international pilot study of schizophrenia. Psychol Med 24(1):133–144CrossRefPubMed Manton KG, Korten A, Woodbury MA, Anker M, Jablensky A (1994) Symptom profiles of psychiatric disorders based on graded disease classes: an illustration using data from the WHO international pilot study of schizophrenia. Psychol Med 24(1):133–144CrossRefPubMed
27.
go back to reference Möller HJ (2003) Bipolar disorder and schizophrenia: distinct illnesses or a continuum? J Clin Psychiatry 64(6):23–27PubMed Möller HJ (2003) Bipolar disorder and schizophrenia: distinct illnesses or a continuum? J Clin Psychiatry 64(6):23–27PubMed
28.
go back to reference Möller HJ (2008) System of psychiatric disorders between categorical and dimensional approaches: Kraepelin’s dichotomy and beyond. Eur Arch Psychiatry Clin Neurosci 258(2):48–73CrossRefPubMed Möller HJ (2008) System of psychiatric disorders between categorical and dimensional approaches: Kraepelin’s dichotomy and beyond. Eur Arch Psychiatry Clin Neurosci 258(2):48–73CrossRefPubMed
29.
go back to reference Möller HJ (2009) Standardised rating scales in psychiatry: methodological basis, possibilities, limitations and descriptions of important rating scales. World J Biol Psychiatry 10(1):6–26CrossRefPubMed Möller HJ (2009) Standardised rating scales in psychiatry: methodological basis, possibilities, limitations and descriptions of important rating scales. World J Biol Psychiatry 10(1):6–26CrossRefPubMed
30.
go back to reference Morrison JR (1995) DSM-IV made easy. Guilford Press, New York Morrison JR (1995) DSM-IV made easy. Guilford Press, New York
31.
go back to reference Murray V, McKee I, Miller PM et al (2005) Dimensions and classes of psychosis in a population cohort: a four-class, four-dimension model of schizophrenia and affective psychoses. Psychol Med 35(4):499–510CrossRefPubMed Murray V, McKee I, Miller PM et al (2005) Dimensions and classes of psychosis in a population cohort: a four-class, four-dimension model of schizophrenia and affective psychoses. Psychol Med 35(4):499–510CrossRefPubMed
32.
go back to reference Musalek M (2005) Die unterschiedliche Herkunft von Schizophrenien und ihre philosophischen Grundlagen. Fortschr Neurol Psychiatr 73(1):S16–S24CrossRefPubMed Musalek M (2005) Die unterschiedliche Herkunft von Schizophrenien und ihre philosophischen Grundlagen. Fortschr Neurol Psychiatr 73(1):S16–S24CrossRefPubMed
33.
go back to reference Pietzcker A, Gebhardt R, Strauss A, Stöckel M, Langer C, Freudenthal K (1983) The syndrome scales in the AMDP-system. In: Bobon D, Baumann U, Angst J, Helmchen H, Hippius H (eds) The AMDP-system in pharmacopsychiatry. Karger, Basel, pp 88–99 Pietzcker A, Gebhardt R, Strauss A, Stöckel M, Langer C, Freudenthal K (1983) The syndrome scales in the AMDP-system. In: Bobon D, Baumann U, Angst J, Helmchen H, Hippius H (eds) The AMDP-system in pharmacopsychiatry. Karger, Basel, pp 88–99
34.
go back to reference Pope HG Jr, Lipinski JF, Cohen BM, Axelrod DT (1980) “Schizoaffective disorder”: an invalid diagnosis? A comparison of schizoaffective disorder, schizophrenia and affective disorder. Am J Psychiatry 137:921–927PubMed Pope HG Jr, Lipinski JF, Cohen BM, Axelrod DT (1980) “Schizoaffective disorder”: an invalid diagnosis? A comparison of schizoaffective disorder, schizophrenia and affective disorder. Am J Psychiatry 137:921–927PubMed
35.
go back to reference Regier DA (2007) Dimensional approaches to psychiatric classification: refining the research agenda for DSM-V: an introduction. Int J Methods Psychiatr Res 16(1):S1–S5CrossRefPubMed Regier DA (2007) Dimensional approaches to psychiatric classification: refining the research agenda for DSM-V: an introduction. Int J Methods Psychiatr Res 16(1):S1–S5CrossRefPubMed
36.
go back to reference Salvatore P, Khalsa HMK, Hennen J et al (2007) Psychopathology factors in first-episode affective and non-affective psychotic disorders. J Psychiatr Res 41(9):724–736CrossRefPubMed Salvatore P, Khalsa HMK, Hennen J et al (2007) Psychopathology factors in first-episode affective and non-affective psychotic disorders. J Psychiatr Res 41(9):724–736CrossRefPubMed
37.
go back to reference Sato T, Bottlender R, Kleindienst N, Möller HJ (2002) Syndromes and phenomenological subtypes underlying acute mania: a factor analytic study of 576 manic patients. Am J Psychiatry 159(6):968–974CrossRefPubMed Sato T, Bottlender R, Kleindienst N, Möller HJ (2002) Syndromes and phenomenological subtypes underlying acute mania: a factor analytic study of 576 manic patients. Am J Psychiatry 159(6):968–974CrossRefPubMed
38.
go back to reference van der Heijden FM, Tuinier S, Arts NJ, Hoogendoorn ML, Kahn RS, Verhoeven WM (2005) Catatonia: disappeared or under-diagnosed? Psychopathology 38(1):3–8CrossRefPubMed van der Heijden FM, Tuinier S, Arts NJ, Hoogendoorn ML, Kahn RS, Verhoeven WM (2005) Catatonia: disappeared or under-diagnosed? Psychopathology 38(1):3–8CrossRefPubMed
39.
go back to reference Vieta E, Phillips ML (2007) Deconstructing bipolar disorder: a critical review of its diagnostic validity and a proposal for DSM-V and ICD-11. Schizophr Bull 33(4):886–892CrossRefPubMed Vieta E, Phillips ML (2007) Deconstructing bipolar disorder: a critical review of its diagnostic validity and a proposal for DSM-V and ICD-11. Schizophr Bull 33(4):886–892CrossRefPubMed
40.
go back to reference Widiger TA, Samuel DB (2005) Diagnostic categories or dimensions? A question for the diagnostic and statistical manual of mental disorders—fifth edition. J Abnorm Psychol 114(4):494–504CrossRefPubMed Widiger TA, Samuel DB (2005) Diagnostic categories or dimensions? A question for the diagnostic and statistical manual of mental disorders—fifth edition. J Abnorm Psychol 114(4):494–504CrossRefPubMed
41.
go back to reference World Health Organization (1992) ICD-10 classification of mental and behavioural disorders: clinical descriptions and diagnostic guidelines. Geneva: World Health Organization World Health Organization (1992) ICD-10 classification of mental and behavioural disorders: clinical descriptions and diagnostic guidelines. Geneva: World Health Organization
Metadata
Title
Combining the categorical and the dimensional perspective in a diagnostic map of psychotic disorders
Authors
Damian Läge
Samy Egli
Michael Riedel
Anton Strauss
Hans-Jürgen Möller
Publication date
01-02-2011
Publisher
Springer-Verlag
Published in
European Archives of Psychiatry and Clinical Neuroscience / Issue 1/2011
Print ISSN: 0940-1334
Electronic ISSN: 1433-8491
DOI
https://doi.org/10.1007/s00406-010-0125-y

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