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Published in: European Archives of Psychiatry and Clinical Neuroscience 3/2010

01-04-2010 | Original Paper

Two subgroups of schizophrenia identified by systematic cognitive neuropsychiatric mapping

Authors: István Szendi, Mihály Racsmány, Csongor Cimmer, Gábor Csifcsák, Zoltán Ambrus Kovács, György Szekeres, Gabriella Galsi, Ferenc Tóth, Attila Nagy, Edit Anna Garab, Krisztina Boda, Gergely Gulyás, József Géza Kiss, József Dombi, Csaba Pléh, Zoltán Janka

Published in: European Archives of Psychiatry and Clinical Neuroscience | Issue 3/2010

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Abstract

The description of the heterogeneous phenomenological, pathophysiological, and etiological nature of schizophrenia is under way; however, the relationships between heterogeneity levels are still unclear. We performed a robust cross-sectional study, including a systematic neuropsychological battery, assessment of clinical symptoms, neurological soft signs, morphogenetic anomalies and smell identification, and measurement of event-related potentials on 50 outpatients with schizophrenia in their compensated states. An explorative fuzzy cluster analysis revealed two subgroups in this sample that could be distinguished from each other on symptomatological, cognitive and neurological levels. The patterns of cognitive dysfunctions and neurological developmental anomalies equally indicate that there may be hemispherical differences between the patients belonging to the different clusters.
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Metadata
Title
Two subgroups of schizophrenia identified by systematic cognitive neuropsychiatric mapping
Authors
István Szendi
Mihály Racsmány
Csongor Cimmer
Gábor Csifcsák
Zoltán Ambrus Kovács
György Szekeres
Gabriella Galsi
Ferenc Tóth
Attila Nagy
Edit Anna Garab
Krisztina Boda
Gergely Gulyás
József Géza Kiss
József Dombi
Csaba Pléh
Zoltán Janka
Publication date
01-04-2010
Publisher
Springer-Verlag
Published in
European Archives of Psychiatry and Clinical Neuroscience / Issue 3/2010
Print ISSN: 0940-1334
Electronic ISSN: 1433-8491
DOI
https://doi.org/10.1007/s00406-009-0073-6

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