Published in:
01-04-2010 | Original Paper
Two subgroups of schizophrenia identified by systematic cognitive neuropsychiatric mapping
Authors:
István Szendi, Mihály Racsmány, Csongor Cimmer, Gábor Csifcsák, Zoltán Ambrus Kovács, György Szekeres, Gabriella Galsi, Ferenc Tóth, Attila Nagy, Edit Anna Garab, Krisztina Boda, Gergely Gulyás, József Géza Kiss, József Dombi, Csaba Pléh, Zoltán Janka
Published in:
European Archives of Psychiatry and Clinical Neuroscience
|
Issue 3/2010
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Abstract
The description of the heterogeneous phenomenological, pathophysiological, and etiological nature of schizophrenia is under way; however, the relationships between heterogeneity levels are still unclear. We performed a robust cross-sectional study, including a systematic neuropsychological battery, assessment of clinical symptoms, neurological soft signs, morphogenetic anomalies and smell identification, and measurement of event-related potentials on 50 outpatients with schizophrenia in their compensated states. An explorative fuzzy cluster analysis revealed two subgroups in this sample that could be distinguished from each other on symptomatological, cognitive and neurological levels. The patterns of cognitive dysfunctions and neurological developmental anomalies equally indicate that there may be hemispherical differences between the patients belonging to the different clusters.