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European Archives of Oto-Rhino-Laryngology

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01-12-2018 | Rhinology

Olfactory bulbus volume and olfactory sulcus depth in psychotic patients and patients with anxiety disorder/depression

Authors: Neşe Asal, Nuray Bayar Muluk, Mikail Inal, Mehmet Hamdi Şahan, Adil Doğan, Sadiye Visal Buturak

Published in: European Archives of Oto-Rhino-Laryngology | Issue 12/2018

Abstract

Objectives

In the present study, we investigated olfactory bulb (OB) volume and olfactory sulcus (OS) depth of the psychotic patients (predominantly schizophrenia) and patients with anxiety disorder/depression.

Methods

This study was conducted retrospectively. Group 1 consisted of 30 psychotic patients (predominantly schizophrenia) (19 males and 11 females). Group 2 consisted of 37 patients with anxiety disorder/depression (10 males, 27 females). Group 3 consisted of 30 non-psychotic and non-anxiety disorder/depression subjects (9 males and 21 females). OB volume and OS depth measurements were performed on Cranial MRI.

Results

OB volume (right and left) of the psychotic; and anxiety disorder/depression groups were significantly lower than those of the control group (p_adjusted < 0.0175). OS depth (Left) value of anxiety disorder/depression group was significantly lower than those of the control group (p_adjusted < 0.0175). In psychotic and anxiety disorder/depression groups, left OS depth values were significantly lower than those of the right side (p < 0.05). In each of the males and females of the anxiety disorder/depression group, left OS depth values were significantly lower than those of the right side (p < 0.05). In psychotic group, OS depth (left) values get lower in older patients (p < 0.05).

Conclusion

Decreased OB volume in the psychotic patients and decreased OB volume and OS depth in anxiety disorder/depression patients were detected. Lower OB volume and OS depth are related to the olfactory loss/or olfactory impairment. Physicians should be aware of the olfactory deficits in psychotic patients (mainly schizophrenia) and patients with anxiety disorder/depression. When reduced OB volume is detected on MRI, psychosis, schizophrenia or depression should also be kept in mind and the patients should be evaluated in detail for these diseases.

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Title: Olfactory bulbus volume and olfactory sulcus depth in psychotic patients and patients with anxiety disorder/depression
Authors: Neşe Asal
Nuray Bayar Muluk
Mikail Inal
Mehmet Hamdi Şahan
Adil Doğan
Sadiye Visal Buturak
Publication date: 01-12-2018
Publisher: Springer Berlin Heidelberg
Published in: European Archives of Oto-Rhino-Laryngology / Issue 12/2018
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-018-5187-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Olfactory bulbus volume and olfactory sulcus depth in psychotic patients and patients with anxiety disorder/depression

Abstract

Objectives

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusion

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