Skip to main content
Top
Published in: European Archives of Oto-Rhino-Laryngology 5/2015

01-05-2015 | Miscellaneous

Automated and objective action coding of facial expressions in patients with acute facial palsy

Authors: Daniel Haase, Laura Minnigerode, Gerd Fabian Volk, Joachim Denzler, Orlando Guntinas-Lichius

Published in: European Archives of Oto-Rhino-Laryngology | Issue 5/2015

Login to get access

Abstract

Aim of the present observational single center study was to objectively assess facial function in patients with idiopathic facial palsy with a new computer-based system that automatically recognizes action units (AUs) defined by the Facial Action Coding System (FACS). Still photographs using posed facial expressions of 28 healthy subjects and of 299 patients with acute facial palsy were automatically analyzed for bilateral AU expression profiles. All palsies were graded with the House–Brackmann (HB) grading system and with the Stennert Index (SI). Changes of the AU profiles during follow-up were analyzed for 77 patients. The initial HB grading of all patients was 3.3 ± 1.2. SI at rest was 1.86 ± 1.3 and during motion 3.79 ± 4.3. Healthy subjects showed a significant AU asymmetry score of 21 ± 11 % and there was no significant difference to patients (p = 0.128). At initial examination of patients, the number of activated AUs was significantly lower on the paralyzed side than on the healthy side (p < 0.0001). The final examination for patients took place 4 ± 6 months post baseline. The number of activated AUs and the ratio between affected and healthy side increased significantly between baseline and final examination (both p < 0.0001). The asymmetry score decreased between baseline and final examination (p < 0.0001). The number of activated AUs on the healthy side did not change significantly (p = 0.779). Radical rethinking in facial grading is worthwhile: automated FACS delivers fast and objective global and regional data on facial motor function for use in clinical routine and clinical trials.
Appendix
Available only for authorised users
Literature
1.
go back to reference Linstrom CJ (2002) Objective facial motion analysis in patients with facial nerve dysfunction. The Laryngoscope 112:1129–1147CrossRefPubMed Linstrom CJ (2002) Objective facial motion analysis in patients with facial nerve dysfunction. The Laryngoscope 112:1129–1147CrossRefPubMed
2.
go back to reference House JW, Brackmann DE (1985) Facial nerve grading system. Otolaryngol Head Neck Surg 93:146–147PubMed House JW, Brackmann DE (1985) Facial nerve grading system. Otolaryngol Head Neck Surg 93:146–147PubMed
3.
go back to reference Ross BG, Fradet G, Nedzelski JM (1996) Development of a sensitive clinical facial grading system. Otolaryngol Head Neck Surg 114:380–386CrossRefPubMed Ross BG, Fradet G, Nedzelski JM (1996) Development of a sensitive clinical facial grading system. Otolaryngol Head Neck Surg 114:380–386CrossRefPubMed
4.
go back to reference Vrabec JT, Backous DD, Djalilian HR et al (2009) Facial Nerve Grading System 2.0. Otolaryngol Head Neck Surg 140:445–450CrossRefPubMed Vrabec JT, Backous DD, Djalilian HR et al (2009) Facial Nerve Grading System 2.0. Otolaryngol Head Neck Surg 140:445–450CrossRefPubMed
5.
go back to reference Stennert E, Fisch U (1977) Facial nerve paralysis scoring system. In: Facial Nerve Surgery. Aesculapius Publishing, Zurich Stennert E, Fisch U (1977) Facial nerve paralysis scoring system. In: Facial Nerve Surgery. Aesculapius Publishing, Zurich
6.
go back to reference Hato N, Fujiwara T, Gyo K et al (2014) Yanagihara facial nerve grading system as a prognostic tool in Bell’s Palsy. Otol Neurot 35:1669–1672CrossRef Hato N, Fujiwara T, Gyo K et al (2014) Yanagihara facial nerve grading system as a prognostic tool in Bell’s Palsy. Otol Neurot 35:1669–1672CrossRef
7.
go back to reference Lee LN, Susarla SM, HH M et al (2013) A comparison of facial nerve grading systems. Ann Plast Surg 70:313–316PubMed Lee LN, Susarla SM, HH M et al (2013) A comparison of facial nerve grading systems. Ann Plast Surg 70:313–316PubMed
8.
go back to reference Berg T, Marsk E, Engstrom M et al (2009) The effect of study design and analysis methods on recovery rates in Bell’s palsy. Laryngoscope 119:2046–2050CrossRefPubMed Berg T, Marsk E, Engstrom M et al (2009) The effect of study design and analysis methods on recovery rates in Bell’s palsy. Laryngoscope 119:2046–2050CrossRefPubMed
9.
go back to reference Neely JG, Cheung JY, Wood M et al (1992) Computerized quantitative dynamic analysis of facial motion in the paralyzed and synkinetic face. Am J Otol 13:97–107PubMed Neely JG, Cheung JY, Wood M et al (1992) Computerized quantitative dynamic analysis of facial motion in the paralyzed and synkinetic face. Am J Otol 13:97–107PubMed
10.
go back to reference Frey M, Jenny A, Giovanoli P et al (1994) Development of a new documentation system for facial movements as a basis for the international registry for neuromuscular reconstruction in the face. Plast Reconstruct Surg 93:1334–1349CrossRef Frey M, Jenny A, Giovanoli P et al (1994) Development of a new documentation system for facial movements as a basis for the international registry for neuromuscular reconstruction in the face. Plast Reconstruct Surg 93:1334–1349CrossRef
11.
go back to reference Meier-Gallati V, Scriba H, Fisch U (1998) Objective scaling of facial nerve function based on area analysis (OSCAR). Otolaryngol Head Neck Surg 118:545–550PubMed Meier-Gallati V, Scriba H, Fisch U (1998) Objective scaling of facial nerve function based on area analysis (OSCAR). Otolaryngol Head Neck Surg 118:545–550PubMed
12.
go back to reference Wachtman GS, Cohn JF, Vanswearingen JM et al (2001) Automated tracking of facial features in patients with facial neuromuscular dysfunction. Plast Reconstruct Surg 107:1124–1133CrossRef Wachtman GS, Cohn JF, Vanswearingen JM et al (2001) Automated tracking of facial features in patients with facial neuromuscular dysfunction. Plast Reconstruct Surg 107:1124–1133CrossRef
13.
go back to reference Hadlock TA, Urban LS (2012) Toward a universal, automated facial measurement tool in facial reanimation. Arch Facial Plast Surg 14:277–282CrossRefPubMed Hadlock TA, Urban LS (2012) Toward a universal, automated facial measurement tool in facial reanimation. Arch Facial Plast Surg 14:277–282CrossRefPubMed
14.
go back to reference Neely JG, Wang KX, Shapland CA et al (2010) Computerized objective measurement of facial motion: normal variation and test-retest reliability. Otol Neurotol 31:1488–1492PubMed Neely JG, Wang KX, Shapland CA et al (2010) Computerized objective measurement of facial motion: normal variation and test-retest reliability. Otol Neurotol 31:1488–1492PubMed
15.
go back to reference O’reilly BF, Soraghan JJ, Mcgrenary S et al (2010) Objective method of assessing and presenting the House-Brackmann and regional grades of facial palsy by production of a facogram. Otol Neurotol 31:486–491CrossRefPubMed O’reilly BF, Soraghan JJ, Mcgrenary S et al (2010) Objective method of assessing and presenting the House-Brackmann and regional grades of facial palsy by production of a facogram. Otol Neurotol 31:486–491CrossRefPubMed
16.
go back to reference Ekman P, Friesen WV (1978) Manual of the Facial Action Coding System (FACS). Consulting Psychologists Press, Palo Alto Ekman P, Friesen WV (1978) Manual of the Facial Action Coding System (FACS). Consulting Psychologists Press, Palo Alto
17.
go back to reference Cohn JF, Zlochower AJ, Lien J et al (1999) Automated face analysis by feature point tracking has high concurrent validity with manual FACS coding. Psychophysiology 36:35–43CrossRefPubMed Cohn JF, Zlochower AJ, Lien J et al (1999) Automated face analysis by feature point tracking has high concurrent validity with manual FACS coding. Psychophysiology 36:35–43CrossRefPubMed
18.
go back to reference Hamm J, Kohler CG, Gur RC et al (2011) Automated Facial Action Coding System for dynamic analysis of facial expressions in neuropsychiatric disorders. J Neurosci Meth 200:237–256CrossRef Hamm J, Kohler CG, Gur RC et al (2011) Automated Facial Action Coding System for dynamic analysis of facial expressions in neuropsychiatric disorders. J Neurosci Meth 200:237–256CrossRef
19.
go back to reference Rogers CR, Schmidt KL, Vanswearingen JM et al (2007) Automated facial image analysis: detecting improvement in abnormal facial movement after treatment with botulinum toxin A. Ann Plast Surg 58:39–47CrossRefPubMed Rogers CR, Schmidt KL, Vanswearingen JM et al (2007) Automated facial image analysis: detecting improvement in abnormal facial movement after treatment with botulinum toxin A. Ann Plast Surg 58:39–47CrossRefPubMed
20.
go back to reference Haase D, Kemmler M, Guntinas Lichius O et al (2012) Measuring Facial Action Unit Activation Intensities using Active Appearance Models. In: German Association for Pattern Recognition (DAGM) Conference, August 28–31, 2012. Graz, Austria Haase D, Kemmler M, Guntinas Lichius O et al (2012) Measuring Facial Action Unit Activation Intensities using Active Appearance Models. In: German Association for Pattern Recognition (DAGM) Conference, August 28–31, 2012. Graz, Austria
21.
go back to reference Volk GF, Klingner C, Finkensieper M et al (2013) Prognostication of recovery time after acute peripheral facial palsy: a prospective cohort study. BMJ Open 3. doi:10.1136/bmjopen-2013-003007 (pii: e003007) Volk GF, Klingner C, Finkensieper M et al (2013) Prognostication of recovery time after acute peripheral facial palsy: a prospective cohort study. BMJ Open 3. doi:10.​1136/​bmjopen-2013-003007 (pii: e003007)
22.
go back to reference Grosheva M, Wittekindt C, Guntinas-Lichius O (2008) Prognostic value of electroneurography and electromyography in facial palsy. Laryngoscope 118:394–397CrossRefPubMed Grosheva M, Wittekindt C, Guntinas-Lichius O (2008) Prognostic value of electroneurography and electromyography in facial palsy. Laryngoscope 118:394–397CrossRefPubMed
23.
go back to reference Sullivan FM, Swan IR, Donnan PT et al (2007) Early treatment with prednisolone or acyclovir in Bell’s palsy. New Engl J Med 357:1598–1607CrossRefPubMed Sullivan FM, Swan IR, Donnan PT et al (2007) Early treatment with prednisolone or acyclovir in Bell’s palsy. New Engl J Med 357:1598–1607CrossRefPubMed
24.
go back to reference Stennert E, Limberg CH, Frentrup KP (1977) An index for paresis and defective healing: an easily applied method for objectively determining therapeutic results in facial paresis (author’s transl). HNO 25:238–245PubMed Stennert E, Limberg CH, Frentrup KP (1977) An index for paresis and defective healing: an easily applied method for objectively determining therapeutic results in facial paresis (author’s transl). HNO 25:238–245PubMed
25.
go back to reference Cootes TF, Edwards CA (2001) Active appearance models. IEEE Trans Pattern Anal Mach Intel 23:681–685CrossRef Cootes TF, Edwards CA (2001) Active appearance models. IEEE Trans Pattern Anal Mach Intel 23:681–685CrossRef
26.
go back to reference Lucey P, Cohn JF, Kanade T et al (2010) The extended cohn-kanade dataset (CK+): a complete dataset for action unit and emotion-specified expression. Comput Vision Pattern Recog Workshops:94–101 Lucey P, Cohn JF, Kanade T et al (2010) The extended cohn-kanade dataset (CK+): a complete dataset for action unit and emotion-specified expression. Comput Vision Pattern Recog Workshops:94–101
27.
go back to reference Matthews I, Baker S (2004) Active appearance models revisited. Int J Comput Vis 60:135–164CrossRef Matthews I, Baker S (2004) Active appearance models revisited. Int J Comput Vis 60:135–164CrossRef
28.
go back to reference Rasmussen CE, Williams CKI (2005) Gaussian processes for machine learning. MIT Press, Cambridge Rasmussen CE, Williams CKI (2005) Gaussian processes for machine learning. MIT Press, Cambridge
29.
go back to reference Ashraf AB, Lucey S, Cohn JF et al (2009) The painful face-pain expression recognition using active appearance models. Image Vision Comput 27:1788–1796CrossRef Ashraf AB, Lucey S, Cohn JF et al (2009) The painful face-pain expression recognition using active appearance models. Image Vision Comput 27:1788–1796CrossRef
31.
go back to reference Van Gelder RS, Borod JC (1990) Neurobiological and cultural aspects of facial asymmetry. J Commun Dis 23:273–286CrossRef Van Gelder RS, Borod JC (1990) Neurobiological and cultural aspects of facial asymmetry. J Commun Dis 23:273–286CrossRef
32.
go back to reference Richardson CK, Bowers D, Bauer RM et al (2000) Digitizing the moving face during dynamic displays of emotion. Neuropsychologia 38:1028–1039CrossRefPubMed Richardson CK, Bowers D, Bauer RM et al (2000) Digitizing the moving face during dynamic displays of emotion. Neuropsychologia 38:1028–1039CrossRefPubMed
33.
go back to reference Hager JC, Ekman P (2005) The asymmetry of facial actions is inconsistent with models of hemispheric specialization. In: Ekman P, Rosenberg EL (eds) What the face reveals. Oxford University Press, Oxford Hager JC, Ekman P (2005) The asymmetry of facial actions is inconsistent with models of hemispheric specialization. In: Ekman P, Rosenberg EL (eds) What the face reveals. Oxford University Press, Oxford
34.
go back to reference Volk GF, Karamyan I, Klingner CM et al (2014) Quantitative magnetic resonance imaging volumetry of facial muscles in healthy patients with facial palsy. Plast Reconstruct Surg Glob Open 2(6):e173. doi:10.1097/GOX.0000000000000128 Volk GF, Karamyan I, Klingner CM et al (2014) Quantitative magnetic resonance imaging volumetry of facial muscles in healthy patients with facial palsy. Plast Reconstruct Surg Glob Open 2(6):e173. doi:10.​1097/​GOX.​0000000000000128​
35.
go back to reference Volk GF, Sauer M, Pohlmann M et al (2014) Reference values for dynamic facial muscle ultrasonography in adults. Muscle Nerve 50:348–357CrossRefPubMed Volk GF, Sauer M, Pohlmann M et al (2014) Reference values for dynamic facial muscle ultrasonography in adults. Muscle Nerve 50:348–357CrossRefPubMed
36.
go back to reference Schumann NP, Bongers K, Guntinas-Lichius O et al (2010) Facial muscle activation patterns in healthy male humans: a multi-channel surface EMG study. J Neuroscience Meth 187:120–128CrossRef Schumann NP, Bongers K, Guntinas-Lichius O et al (2010) Facial muscle activation patterns in healthy male humans: a multi-channel surface EMG study. J Neuroscience Meth 187:120–128CrossRef
37.
go back to reference Kim SW, Heller ES, Hohman MH et al (2013) Detection and perceptual impact of side-to-side facial movement asymmetry. Facial Plast Surg 15:411–416CrossRef Kim SW, Heller ES, Hohman MH et al (2013) Detection and perceptual impact of side-to-side facial movement asymmetry. Facial Plast Surg 15:411–416CrossRef
38.
go back to reference Hohman MH, Kim SW, Heller ES et al (2014) Determining the threshold for asymmetry detection in facial expressions. Laryngoscope 124:860–865CrossRefPubMed Hohman MH, Kim SW, Heller ES et al (2014) Determining the threshold for asymmetry detection in facial expressions. Laryngoscope 124:860–865CrossRefPubMed
39.
go back to reference Engstrom M, Berg T, Stjernquist-Desatnik A et al (2008) Prednisolone and valaciclovir in Bell’s palsy: a randomised, double-blind, placebo-controlled, multicentre trial. Lancet Neurol 7:993–1000CrossRefPubMed Engstrom M, Berg T, Stjernquist-Desatnik A et al (2008) Prednisolone and valaciclovir in Bell’s palsy: a randomised, double-blind, placebo-controlled, multicentre trial. Lancet Neurol 7:993–1000CrossRefPubMed
40.
go back to reference Heckmann JG, Lang C, Glocker FX et al (2012) The new S2 k AWMF guideline for the treatment of Bell’s palsy in commented short form. Laryngorhinootol 91:686–692CrossRef Heckmann JG, Lang C, Glocker FX et al (2012) The new S2 k AWMF guideline for the treatment of Bell’s palsy in commented short form. Laryngorhinootol 91:686–692CrossRef
41.
go back to reference Gronseth GS, Paduga R, American Academy Of N (2012) Evidence-based guideline update: steroids and antivirals for Bell palsy: report of the Guideline Development Subcommittee of the American Academy of Neurology. Neurology 79:2209–2213CrossRefPubMed Gronseth GS, Paduga R, American Academy Of N (2012) Evidence-based guideline update: steroids and antivirals for Bell palsy: report of the Guideline Development Subcommittee of the American Academy of Neurology. Neurology 79:2209–2213CrossRefPubMed
42.
go back to reference Baugh RF, Basura GJ, Ishii LE et al (2013) Clinical practice guideline: Bell’s palsy. Otolaryngol Head Neck Surg 149:S1–S27CrossRefPubMed Baugh RF, Basura GJ, Ishii LE et al (2013) Clinical practice guideline: Bell’s palsy. Otolaryngol Head Neck Surg 149:S1–S27CrossRefPubMed
43.
go back to reference Deleyiannis FW, Askari M, Schmidt KL et al (2005) Muscle activity in the partially paralyzed face after placement of a fascial sling: a preliminary report. Ann Plast Surg 55:449–455CrossRefPubMed Deleyiannis FW, Askari M, Schmidt KL et al (2005) Muscle activity in the partially paralyzed face after placement of a fascial sling: a preliminary report. Ann Plast Surg 55:449–455CrossRefPubMed
44.
go back to reference He S, Soraghan JJ, O’reilly BF et al (2009) Quantitative analysis of facial paralysis using local binary patterns in biomedical videos. IEEE Trans Biomed Engin 56:1864–1870CrossRef He S, Soraghan JJ, O’reilly BF et al (2009) Quantitative analysis of facial paralysis using local binary patterns in biomedical videos. IEEE Trans Biomed Engin 56:1864–1870CrossRef
45.
go back to reference Sawai N, Hato N, Hakuba N et al (2012) Objective assessment of the severity of unilateral facial palsy using OKAO Vision® facial image analysis software. Acta Otolaryngol 132:1013–1017CrossRefPubMed Sawai N, Hato N, Hakuba N et al (2012) Objective assessment of the severity of unilateral facial palsy using OKAO Vision® facial image analysis software. Acta Otolaryngol 132:1013–1017CrossRefPubMed
46.
go back to reference Mabvuure NT, Hallam MJ, Venables V et al (2013) Validation of a new photogrammetric technique to monitor the treatment effect of Botulinum toxin in synkinesis. Eye 27:860–864CrossRefPubMedCentralPubMed Mabvuure NT, Hallam MJ, Venables V et al (2013) Validation of a new photogrammetric technique to monitor the treatment effect of Botulinum toxin in synkinesis. Eye 27:860–864CrossRefPubMedCentralPubMed
47.
go back to reference Dulguerov P, Wang D, Perneger TV et al (2003) Videomimicography: the standards of normal revised. Arch Otolaryngol Head Neck Surg 129:960–965CrossRefPubMed Dulguerov P, Wang D, Perneger TV et al (2003) Videomimicography: the standards of normal revised. Arch Otolaryngol Head Neck Surg 129:960–965CrossRefPubMed
48.
go back to reference Ferrario VF, Sforza C (2007) Anatomy of emotion: a 3D study of facial mimicry. Eur J Histochem EJH 51(Suppl 1):45–52 Ferrario VF, Sforza C (2007) Anatomy of emotion: a 3D study of facial mimicry. Eur J Histochem EJH 51(Suppl 1):45–52
49.
go back to reference Denlinger RL, Vanswearingen JM, Cohn JF et al (2008) Puckering and blowing facial expressions in people with facial movement disorders. Phys Ther 88:909–915CrossRefPubMedCentralPubMed Denlinger RL, Vanswearingen JM, Cohn JF et al (2008) Puckering and blowing facial expressions in people with facial movement disorders. Phys Ther 88:909–915CrossRefPubMedCentralPubMed
50.
go back to reference Beurskens CH, Oosterhof J, Nijhuis-Van Der Sanden MW (2010) Frequency and location of synkineses in patients with peripheral facial nerve paresis. Otol Neurotol 31:671–675PubMed Beurskens CH, Oosterhof J, Nijhuis-Van Der Sanden MW (2010) Frequency and location of synkineses in patients with peripheral facial nerve paresis. Otol Neurotol 31:671–675PubMed
Metadata
Title
Automated and objective action coding of facial expressions in patients with acute facial palsy
Authors
Daniel Haase
Laura Minnigerode
Gerd Fabian Volk
Joachim Denzler
Orlando Guntinas-Lichius
Publication date
01-05-2015
Publisher
Springer Berlin Heidelberg
Published in
European Archives of Oto-Rhino-Laryngology / Issue 5/2015
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-014-3385-8

Other articles of this Issue 5/2015

European Archives of Oto-Rhino-Laryngology 5/2015 Go to the issue