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European Archives of Oto-Rhino-Laryngology
Published in: European Archives of Oto-Rhino-Laryngology 8/2010

01-08-2010 | Review Article

Age-related hearing loss or presbycusis

Authors: Qi Huang, Jianguo Tang

Published in: European Archives of Oto-Rhino-Laryngology | Issue 8/2010

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Abstract

Aging is a natural consequence of a society developing process. Although many adults retain good hearing as they aging, hearing loss related with age–presbycusis which can vary in severity from mild to substantial is common among elderly persons. There are a number of pathophysiological processes underlying age-related changes in the auditory system as well as in the central nervous systems. Many studies have been dedicated to the illustration of risk factors accumulating presbycusis such as heritability, environment factors, medical conditions, free radical (reactive oxygen species, ROS) and damage of mitochondrial DNA. Left untreated, presbycusis can not only lead sufferers to reduced quality of life, isolation, dependence and frustration, but also affect the healthy people around. These can be partly corrected using hearing aids, but it is not enough, more and more strategies of treatment based on the findings associating with presbycusis should be added rather than using single hearing aids. We review here the pathophysiology; heritability, susceptibility genes and other risk factors including environmental, medical, especially free radical (ROS) and damage of mitochondrial DNA; and some strategies of treatment, as well as promising rehabilitations associating with presbycusis.
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Metadata
Title
Age-related hearing loss or presbycusis
Authors
Qi Huang
Jianguo Tang
Publication date
01-08-2010
Publisher
Springer-Verlag
Published in
European Archives of Oto-Rhino-Laryngology / Issue 8/2010
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-010-1270-7

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Head and Neck

Full-thickness skin grafts and perichondrial cutaneous grafts following surgical removal of cutaneous neoplasms of the head and neck

Head and Neck

Translocation (12;14) and other chromosome abnormalities in squamous cell carcinoma of the tongue

Otology

Necrotizing otitis externa: 19 cases’ report