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01-09-2018 | Gynecologic Endocrinology and Reproductive Medicine

Extraparenchymal ovarian and testicular Leydig cells: ectopic/heterotopic or orthotopic?

Authors: José L. Carrasco-Juan, Hugo Álvarez-Argüelles-Cabrera, Carmen Martín-Corriente, Ricardo Gutiérrez-García, Abián Vega-Falcón, Idaira Expósito-Afonso, Rafael Méndez-Medina, Lucio Díaz-Flores

Published in: Archives of Gynecology and Obstetrics | Issue 3/2018

Abstract

Purpose

We are conducting a prospective study trying to determine, in both sexes, the frequency of appearance of ectopic Leydig cells, their preferred location, their relationship with nerve structures and the possible causes of their appearance.

Methods

We have studied 86 cases that were removed according to different clinical indications for pathological study: uterine leyomiomas (n = 12), ovarian cystadenoma (n = 4), endometrial hyperplasia (n = 8), endometrial carcinoma (n = 12), cervical carcinoma (n = 4), seminoma (n = 4), fallopian tube ligatures (n = 24), vasectomies (n = 8), nonspecific orchiepididymitis (n = 2), and unknown (n = 8).

Results

We have observed ectopic Leydig cells in 13/86 cases (15.11%), 9/72 in the female samples (12.50%) and 4/14 in male samples (28.57%). The most frequent location was the mesosalpinx (4 of 13: 30.76%).

Conclusions

These high figures lead us to believe that the ectopia of Leydig cells is not really a pathologic entity, but a finding related to specific functions yet to be determined.

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Title: Extraparenchymal ovarian and testicular Leydig cells: ectopic/heterotopic or orthotopic?
Authors: José L. Carrasco-Juan
Hugo Álvarez-Argüelles-Cabrera
Carmen Martín-Corriente
Ricardo Gutiérrez-García
Abián Vega-Falcón
Idaira Expósito-Afonso
Rafael Méndez-Medina
Lucio Díaz-Flores
Publication date: 01-09-2018
Publisher: Springer Berlin Heidelberg
Published in: Archives of Gynecology and Obstetrics / Issue 3/2018
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-018-4846-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Extraparenchymal ovarian and testicular Leydig cells: ectopic/heterotopic or orthotopic?

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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