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Archives of Gynecology and Obstetrics

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01-07-2015 | Review

Scientific evaluation of medicinal plants used for the treatment of abnormal uterine bleeding by Avicenna

Authors: Masumeh Mobli, Marzieh Qaraaty, Gholamreza Amin, Ismaeil Haririan, Mannan Hajimahmoodi, Roja Rahimi

Published in: Archives of Gynecology and Obstetrics | Issue 1/2015

Abstract

Purpose

Abnormal uterine bleeding (AUB) is one of the prevalent gynecological disorders that cause considerable morbidity and management of that plays an important role in protecting women’s health. This review focuses on medicinal plants mentioned by Avicenna, a great Iranian philosopher and physician (A.D. 980–1037), in his book Canon for treatment of AUB.

Methods

Medicinal plants mentioned in Canon for treatment of AUB were elicited and searched in electronic databases including PubMed, Scopus, Google Scholar and Cochrane library to find studies that confirmed their efficacy. Data were collected for the years 1980–2014.

Results

The findings included 23 plants belonging to 18 families. Scientific findings have revealed that these plants control AUB through four mechanisms of action including inhibition of inflammatory process, inhibition of prostaglandins production, antiproliferative activity on human cervical cancer cells (HeLa), and estrogenic activity. All of the plants exhibited anti-inflammatory activity in vitro and/or in vivo. Cuscuta chinensis and Portulaca oleracea exhibited estrogenic activity. Boswellia carteri, Lens culinaris, Myrtus communis, Polygonum aviculare, Pistacia lentiscus, and Punica granatum have revealed inhibitory activity on biosynthesis of prostaglandins. Some of the mentioned plants including: Ceratonia siliqua, Cuscuta chinensis, Cuscuta epithymum, Cydonia oblonga, Paeonia sp., Portulaca oleracea, Solanum nigrum, Rumex acetosa and Onopordum acanthium have shown antiproliferative activity on HeLa cells.

Conclusion

Investigation of traditional Iranian medicine literatures can lead to the identification of effective natural medicines for the management of AUB; however, conclusive confirmation of the efficacy and safety of these treatments needs more evaluations.

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Title: Scientific evaluation of medicinal plants used for the treatment of abnormal uterine bleeding by Avicenna
Authors: Masumeh Mobli
Marzieh Qaraaty
Gholamreza Amin
Ismaeil Haririan
Mannan Hajimahmoodi
Roja Rahimi
Publication date: 01-07-2015
Publisher: Springer Berlin Heidelberg
Published in: Archives of Gynecology and Obstetrics / Issue 1/2015
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-015-3629-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Scientific evaluation of medicinal plants used for the treatment of abnormal uterine bleeding by Avicenna

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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