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01-03-2015 | Gynecologic Endocrinology and Reproductive Medicine

Impact of sperm cell source on the results of intracytoplasmic sperm injection

Authors: Christian Gnoth, Vitaly Markhinin, Beatrice Maxrath, Therese Skonieczny, Kerstin Friol, Judith Roos, Gohar Rahimi, Erhard Godehardt

Published in: Archives of Gynecology and Obstetrics | Issue 3/2015

Abstract

Purpose

There is an ongoing debate whether the source of sperm cells, the etiology or the extent of male factor infertility has influence on the outcome of ICSI cycles.

Methods

The results of intracytoplasmic sperm injection (ICSI) according to the source of spermatozoa in patients with severe male factor infertility were compared in a retrospective study: 249 couples underwent a total of 337 fresh ICSI cycles with the use of fresh motile testicular or fresh motile ejaculated spermatozoa.

Results

For all variables, there were no statistically significant differences in the ICSI results between both groups. Fertilization rates were 46.8 % for testicular and 47.6 % for ejaculated spermatozoa. Live birth rates per embryo transfer were 20.4 % using testicular spermatozoa and 22.8 % using ejaculated spermatozoa.

Conclusions

Neither the source of spermatozoa nor the etiology of severe male infertility has relevant impact on the results of ICSI cycles as long as fresh motile, morphologically normal spermatozoa are used. Therefore, in case of cryptozoospermia, we recommend to preferentially use ejaculated spermatozoa to prevent those men from an unnecessary testicular biopsy avoiding risks and costs implied.

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Title: Impact of sperm cell source on the results of intracytoplasmic sperm injection
Authors: Christian Gnoth
Vitaly Markhinin
Beatrice Maxrath
Therese Skonieczny
Kerstin Friol
Judith Roos
Gohar Rahimi
Erhard Godehardt
Publication date: 01-03-2015
Publisher: Springer Berlin Heidelberg
Published in: Archives of Gynecology and Obstetrics / Issue 3/2015
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-014-3448-5

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Impact of sperm cell source on the results of intracytoplasmic sperm injection

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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