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Archives of Gynecology and Obstetrics

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01-03-2012 | General Gynecology

Role of serum interleukin-6 in comparing surgical stress after laparoscopic-assisted vaginal hysterectomy and non-descent vaginal hysterectomy for large uteri

Authors: Kallol Kumar Roy, Murali Subbaiah, Shilpa Singla, Sunesh Kumar, Jai Bhagwan Sharma, Dipender Kumar Mitra

Published in: Archives of Gynecology and Obstetrics | Issue 3/2012

Abstract

Aims and objectives

To compare the perioperative inflammatory response using interleukin-6 (IL-6) in patients of laparoscopic-assisted vaginal hysterectomy (LAVH) and non-descent vaginal hysterectomy (NDVH) for large uteri with benign disease.

Materials and methods

Twenty women with benign uterine disease and failed medical management with size of uterus ranging from 300 to 1,500 g (12–24 weeks) were randomized into two equal groups for either technique of hysterectomy, LAVH and NDVH. Venous blood levels of IL-6 were measured preoperatively and 3, 24 and 72 h after beginning of surgery. Statistical analysis was done using SPSS15 software.

Results

No statistically significant difference was present in demographic characteristics, operating time, and uterine weight between the two groups. No major complications were encountered. The increase in serum interleukin 6 levels from preoperative value to the value at 3 h postoperatively was found to be significantly higher in LAVH group when compared with NDVH group indicating greater tissue handling and trauma in LAVH group.

Conclusion

Non-descent vaginal hysterectomy appears to be better than laparoscopic-assisted vaginal hysterectomy for large uteri in terms of inflammatory response.

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Title: Role of serum interleukin-6 in comparing surgical stress after laparoscopic-assisted vaginal hysterectomy and non-descent vaginal hysterectomy for large uteri
Authors: Kallol Kumar Roy
Murali Subbaiah
Shilpa Singla
Sunesh Kumar
Jai Bhagwan Sharma
Dipender Kumar Mitra
Publication date: 01-03-2012
Publisher: Springer-Verlag
Published in: Archives of Gynecology and Obstetrics / Issue 3/2012
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-011-2001-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Role of serum interleukin-6 in comparing surgical stress after laparoscopic-assisted vaginal hysterectomy and non-descent vaginal hysterectomy for large uteri

Abstract

Aims and objectives

Materials and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Aims and objectives

Materials and methods

Results

Conclusion

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