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Archives of Gynecology and Obstetrics

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01-12-2011 | Materno-fetal Medicine

A comparison of misoprostol, controlled-release dinoprostone vaginal insert and oxytocin for cervical ripening

Authors: Dilek B. Silfeler, Bulent Tandogan, Habibe Ayvaci, Ibrahim Silfeler, Ilter Yenidede, Vedat Dayicioglu

Published in: Archives of Gynecology and Obstetrics | Issue 6/2011

Abstract

Objective

We compared the safety and effectiveness of oxytocin, dinoprostone and misoprostol for cervical priming.

Study design

A total of 218 patients were enrolled to receive between one and three treatments according to physicians’ options. The end points were: (1) vaginal delivery or Bishop score ≥8 at the end of 12 h, (2) vaginal delivery by 12 h or difference ≥4 between the initial and 12th hour Bishop scores. Statistical analyses were performed with ANOVA, Krustal Wallis, Scheffe, χ², Fisher, Advanced χ², and Kolmogorov–Smirnov tests. Tukey’s HSD was used as a post hoc test.

Results

Misoprostol showed statistical significance for the rate of vaginal delivery <12 h, ≥8 Bishop score at the end of 12 h, and cervical change of ≥4 Bishop scores within 12 h (p = 0.013).

Conclusions

Comparison between cases Bishop score <4 showed that misoprostol is more effective than dinoprostone and oxytocin. Considering Bishop score = 0 cases we calculated no statistical significance.

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Title: A comparison of misoprostol, controlled-release dinoprostone vaginal insert and oxytocin for cervical ripening
Authors: Dilek B. Silfeler
Bulent Tandogan
Habibe Ayvaci
Ibrahim Silfeler
Ilter Yenidede
Vedat Dayicioglu
Publication date: 01-12-2011
Publisher: Springer-Verlag
Published in: Archives of Gynecology and Obstetrics / Issue 6/2011
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-011-1844-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

A comparison of misoprostol, controlled-release dinoprostone vaginal insert and oxytocin for cervical ripening

Abstract

Objective

Study design

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Study design

Results

Conclusions

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