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01-11-2011 | Gynecologic Oncology

Metabolic syndrome is an independent risk factor for breast cancer

Authors: Lakymê Ângelo Mangueira Porto, Karla Jamille Bezerra Lora, Juliana Coutinho Miranda Soares, Laura Olinda Bregieiro Fernandes Costa

Published in: Archives of Gynecology and Obstetrics | Issue 5/2011

Abstract

Objective

This study was aimed to assess the prevalence of metabolic syndrome in patients with breast cancer and the independent effect of metabolic syndrome on breast cancer risk.

Methods

Eighty-one women aged 40–80 years with breast cancer and 81 controls of similar age were screened for metabolic syndrome prevalence and breast cancer risk factors, including age at diagnosis, age at menarche, reproductive status, live births, breastfeeding, family history of breast cancer, physical activity, cigarette smoking, body mass index, and metabolic syndrome parameters. Each variable was first assessed for baseline comparisons using the univariate model, and significant variables were then added to the multivariate conditional logistic regression model.

Results

Prevalence of metabolic syndrome was 59.2% in breast cancer patients, and 37% in the control group (p < 0.005). A positive and independent association was observed between metabolic syndrome and breast cancer risk (odds ratio = 2.49; 95% confidence interval 1.17–5.30).

Conclusion

Metabolic syndrome is more prevalent in breast cancer patients and is an independent risk factor for breast cancer.

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Title: Metabolic syndrome is an independent risk factor for breast cancer
Authors: Lakymê Ângelo Mangueira Porto
Karla Jamille Bezerra Lora
Juliana Coutinho Miranda Soares
Laura Olinda Bregieiro Fernandes Costa
Publication date: 01-11-2011
Publisher: Springer-Verlag
Published in: Archives of Gynecology and Obstetrics / Issue 5/2011
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-011-1837-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Metabolic syndrome is an independent risk factor for breast cancer

Abstract

Objective

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Methods

Results

Conclusion

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