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Published in: Archives of Gynecology and Obstetrics 3/2011

01-03-2011 | General Gynecology

Pelvic mass-like florid cystic endosalpingiosis of the uterus: a case report and a review of literature

Authors: Piergiorgio Rosenberg, Luigi Nappi, Angela Santoro, Pantaleo Bufo, Pantaleo Greco

Published in: Archives of Gynecology and Obstetrics | Issue 3/2011

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Abstract

Introduction

Endosalpingiosis is a disorder of Mullerian system characterized by benign glands lined by tubal type epithelium and involves the peritoneum, subperitoneal tissues, and retroperitoneal lymph nodes. Endosalpingiosis is almost an incidental finding on microscopic examination. Seldom it appears as a cyst and it can be confused clinically for an ovarian tumor.

Design

A case report and a systematic review about pelvic mass-like florid endosalpingiosis of the uterus from PUB MED database were performed.

Patient(s)

We describe a case report of a 50-year-old woman with a pedunculated uterine neoformation, for which the preoperative exams could be compatible with an adnexal mass. Twelve patients with similar clinical history were discussed in the review.

Treatment

Laparoscopy with radical exeresis was performed.

Results

Microscopic exam revealed florid cystic endosalpingiosis of the uterus.

Conclusions

Endosalpingiosis is a rare mullerian disorder and the main problem is that the symptomatology is not specific and it may be initially misinterpreted. In relation to the papillary aspect of the lesion and focal calcifications, the histological differential diagnosis could include serous adenocarcinoma, but the lack of cellular stratification in absence of mitotic activity, and the presence of slight nuclear atypia contradict the diagnosis of carcinoma. The differential diagnosis for endosalpingiosis also includes multiple peritoneal inclusion cysts (benign cystic mesothelioma). The aim of this case report has not been only to describe the rarity of this pathology, but it contributes to consider endosalpingiosis as a possible diagnostic hypothesis for which may be indicated a conservative surgical treatment.
Literature
1.
go back to reference Buttram VC Jr, Reiter RC (1981) Uterine leiomyomata: etiology, symptomatology, and management. Fertil Steril 36:433–445PubMed Buttram VC Jr, Reiter RC (1981) Uterine leiomyomata: etiology, symptomatology, and management. Fertil Steril 36:433–445PubMed
2.
go back to reference Koonings PP (1989) Campbell et al. Relative frequency of primary ovarian neoplasms: a 10-year review. Obstet Gynecol 74:921–926PubMed Koonings PP (1989) Campbell et al. Relative frequency of primary ovarian neoplasms: a 10-year review. Obstet Gynecol 74:921–926PubMed
3.
go back to reference Russell P, Farnsworth A (1997) Mullerianosis and reactive mesothelial lesions. Surgical pathology of the ovaries. Churchill Livingstone, New York, pp 195–207 Russell P, Farnsworth A (1997) Mullerianosis and reactive mesothelial lesions. Surgical pathology of the ovaries. Churchill Livingstone, New York, pp 195–207
4.
go back to reference Clement PB (2000) Tumors of the peritoneum. In: Fletcher CDM (ed) Diagnostic histopathology of tumors, vol 1. Churchill Livingstone, London, pp 839–864 Clement PB (2000) Tumors of the peritoneum. In: Fletcher CDM (ed) Diagnostic histopathology of tumors, vol 1. Churchill Livingstone, London, pp 839–864
5.
go back to reference Ong NCS, Maher PJ, Pyman JM, Readman E, Gordon S (2004) Endosalpingiosis, an unrecognized condition: report and literature review. Gynecol Surg 1:11–14 Ong NCS, Maher PJ, Pyman JM, Readman E, Gordon S (2004) Endosalpingiosis, an unrecognized condition: report and literature review. Gynecol Surg 1:11–14
6.
go back to reference Cil AP, Atasoy P, Kara SA (2008) Myometrial involvement of tumor-like cystic endosalpingiosis: a rare entity. Ultrasound Obstet Gynecol 32(1):106–110CrossRefPubMed Cil AP, Atasoy P, Kara SA (2008) Myometrial involvement of tumor-like cystic endosalpingiosis: a rare entity. Ultrasound Obstet Gynecol 32(1):106–110CrossRefPubMed
7.
go back to reference Bryce RL et al (1982) Endosalpingiosis in pregnancy. Case report. Br J Obstet Gynaecol 89(2):166–168CrossRefPubMed Bryce RL et al (1982) Endosalpingiosis in pregnancy. Case report. Br J Obstet Gynaecol 89(2):166–168CrossRefPubMed
8.
go back to reference Young R, Clement P (1996) Mullerianosis of the urinary bladder. Mod Pathol 9:731–737PubMed Young R, Clement P (1996) Mullerianosis of the urinary bladder. Mod Pathol 9:731–737PubMed
9.
go back to reference Cajigas A, Axiotis CA (1990) Endosalpingiosis of the vermiform appendix. Int J Gynecol Pathol 9:291–295CrossRefPubMed Cajigas A, Axiotis CA (1990) Endosalpingiosis of the vermiform appendix. Int J Gynecol Pathol 9:291–295CrossRefPubMed
10.
go back to reference McCluggage WG, Clements WD (2001) Endosalpingiosis of the colon and appendix. Histopathology 39(6):645–646CrossRefPubMed McCluggage WG, Clements WD (2001) Endosalpingiosis of the colon and appendix. Histopathology 39(6):645–646CrossRefPubMed
11.
12.
go back to reference Chang Y, Tsai E-M et al (2003) Multilobular cyst as endosalpingiosis of uterine serosa: case report. Kaohsiung J Med Sci 19(1):38–41CrossRefPubMed Chang Y, Tsai E-M et al (2003) Multilobular cyst as endosalpingiosis of uterine serosa: case report. Kaohsiung J Med Sci 19(1):38–41CrossRefPubMed
13.
go back to reference Fukunaga M (2004) Tumor-like cystic endosalpingiosis of the uterus with florid epithelial proliferation. A case report. Apmis 112(1):45–48CrossRefPubMed Fukunaga M (2004) Tumor-like cystic endosalpingiosis of the uterus with florid epithelial proliferation. A case report. Apmis 112(1):45–48CrossRefPubMed
14.
go back to reference Heatley MK, Russell P (2001) Florid cystic endosalpingiosis of the uterus. J Clin Pathol 54:399–400CrossRefPubMed Heatley MK, Russell P (2001) Florid cystic endosalpingiosis of the uterus. J Clin Pathol 54:399–400CrossRefPubMed
15.
go back to reference Clement PB, Young RH (1999) Florid cystic endosalpingiosis with tumor-like manifestations: a report of four cases including the first reported cases of transmural endosalpingiosis of the uterus. Am J Surg Pathol 23(2):166 Clement PB, Young RH (1999) Florid cystic endosalpingiosis with tumor-like manifestations: a report of four cases including the first reported cases of transmural endosalpingiosis of the uterus. Am J Surg Pathol 23(2):166
16.
go back to reference Lee SN, Cho MS, Kim SC, Han WS (2005) Tumor-like multilocular cystic endosalpingiosis of the uterine serosa: possible clinical and radiologic misinterpreted. Acta Obstet Gynecol Scand 84:98–99PubMed Lee SN, Cho MS, Kim SC, Han WS (2005) Tumor-like multilocular cystic endosalpingiosis of the uterine serosa: possible clinical and radiologic misinterpreted. Acta Obstet Gynecol Scand 84:98–99PubMed
17.
go back to reference Kajo K, Zúbor P et al (2005) Tumor-like manifestation of endosalpingiosis in uterus: a case report. Pathol Res Pract 201(7):527–530CrossRefPubMed Kajo K, Zúbor P et al (2005) Tumor-like manifestation of endosalpingiosis in uterus: a case report. Pathol Res Pract 201(7):527–530CrossRefPubMed
18.
go back to reference Youssef AH, Ganesan R et al (2006) Florid cystic endosalpingiosis of the uterus. Histopathology 49(5):546–548CrossRefPubMed Youssef AH, Ganesan R et al (2006) Florid cystic endosalpingiosis of the uterus. Histopathology 49(5):546–548CrossRefPubMed
19.
go back to reference Batt R, Smith RA et al (2007) Mullerianosis. Histol Histopathol 22(10):1161–1166PubMed Batt R, Smith RA et al (2007) Mullerianosis. Histol Histopathol 22(10):1161–1166PubMed
20.
go back to reference Pickartz H (1991) Tumor-like lesions of the secondary Müllerian system Immunohistochemical investigations and differential diagnosis. APMIS Suppl 23:146–151PubMed Pickartz H (1991) Tumor-like lesions of the secondary Müllerian system Immunohistochemical investigations and differential diagnosis. APMIS Suppl 23:146–151PubMed
21.
go back to reference Driss M, Zhioua F et al (2009) Cotyledonoid dissecting leiomyoma of the uterus associated with endosalpingiosis. Arch Gynecol Obstet 280(6):1063–1065. Epub 2 Apr 2009 Driss M, Zhioua F et al (2009) Cotyledonoid dissecting leiomyoma of the uterus associated with endosalpingiosis. Arch Gynecol Obstet 280(6):1063–1065. Epub 2 Apr 2009
Metadata
Title
Pelvic mass-like florid cystic endosalpingiosis of the uterus: a case report and a review of literature
Authors
Piergiorgio Rosenberg
Luigi Nappi
Angela Santoro
Pantaleo Bufo
Pantaleo Greco
Publication date
01-03-2011
Publisher
Springer-Verlag
Published in
Archives of Gynecology and Obstetrics / Issue 3/2011
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-010-1700-1

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