Skip to main content
Top
Published in: Archives of Gynecology and Obstetrics 3/2009

01-09-2009 | Case Report

Male infertility associated with adult dominant polycystic kidney disease: a case series

Authors: Shai Shefi, Jacob Levron, Andrei Nadu, Gil Raviv

Published in: Archives of Gynecology and Obstetrics | Issue 3/2009

Login to get access

Abstract

Introduction

Although described earlier, the association of male infertility with adult dominant polycystic kidney disease (ADPKD) is quite rare and unfamiliar to some of the multidisciplinary team members caring for affected men.

Materials and methods

Infertile men diagnosed to have ADPKD were evaluated by clinical characteristics including testis volume, as well as serum hormone levels, semen analysis, and transrectal ultrasonography (TRUS) because of low volume ejaculate.

Results

Semen analysis revealed low-normal volume, normal pH, and azoospermia/virtual azoospermia. Serum hormones were within the normal range. Transrectal ultrasonography demonstrated cystic dilatation of the seminal vesicles in all three men.

Conclusion

Patients should be referred for andrological evaluation of a presentation similar to obstructive azoospermia. Their potential to achieve paternity by surgical sperm retrieval combined with assisted reproductive technology is another example of cooperation between andrologists and gynecologists.
Literature
3.
go back to reference Torra R, Sarquella J, Calabia J, Martí J, Ars E, Fernández-Llama P, Ballarin J (2008) Prevalence of cysts in seminal tract and abnormal semen parameters in patients with autosomal dominant polycystic kidney disease. Clin J Am Soc Nephrol 3:790–793. doi:10.2215/CJN.05311107 PubMedCrossRef Torra R, Sarquella J, Calabia J, Martí J, Ars E, Fernández-Llama P, Ballarin J (2008) Prevalence of cysts in seminal tract and abnormal semen parameters in patients with autosomal dominant polycystic kidney disease. Clin J Am Soc Nephrol 3:790–793. doi:10.​2215/​CJN.​05311107 PubMedCrossRef
4.
go back to reference Okeahialam BN, Pam SD, Ekedigwe JE, Ekwempu CC (2006) Familial polycystic kidney disease in Nigeria: a report of two cases. West Afr J Med 25:249–251PubMed Okeahialam BN, Pam SD, Ekedigwe JE, Ekwempu CC (2006) Familial polycystic kidney disease in Nigeria: a report of two cases. West Afr J Med 25:249–251PubMed
5.
go back to reference Handelsman DJ, Dong Q (1993) Hypothalamo-pituitary gonadal axis in chronic renal failure. Endocrinol Metab Clin North Am 22:145–161PubMed Handelsman DJ, Dong Q (1993) Hypothalamo-pituitary gonadal axis in chronic renal failure. Endocrinol Metab Clin North Am 22:145–161PubMed
7.
go back to reference Wagner CA (2008) News from the cyst: insights into polycystic kidney disease. J Nephrol 21:14–16PubMed Wagner CA (2008) News from the cyst: insights into polycystic kidney disease. J Nephrol 21:14–16PubMed
10.
go back to reference Manno M, Marchesan E, Tomei F, Cicutto D, Maruzzi D, Maieron A, Turco A (2005) Polycystic kidney disease and infertility: case report and literature review. Arch Ital Urol Androl 77:25–28PubMed Manno M, Marchesan E, Tomei F, Cicutto D, Maruzzi D, Maieron A, Turco A (2005) Polycystic kidney disease and infertility: case report and literature review. Arch Ital Urol Androl 77:25–28PubMed
11.
go back to reference Raviv G, Mor Y, Levron J, Shefi S, Zilberman D, Ramon J, Madgar I (2006) Role of transrectal ultrasonography in the evaluation of azoospermic men with low-volume ejaculate. J Ultrasound Med 25:825–829PubMed Raviv G, Mor Y, Levron J, Shefi S, Zilberman D, Ramon J, Madgar I (2006) Role of transrectal ultrasonography in the evaluation of azoospermic men with low-volume ejaculate. J Ultrasound Med 25:825–829PubMed
12.
14.
go back to reference Okada H, Fujioka H, Tatsumi N, Fujisawa M, Gohji K, Arakawa S, Kato H, Kobayashi S, Isojima S, Kamidono S (1999) Assisted reproduction for infertile patients with 9 + 0 immotile spermatozoa associated with autosomal dominant polycystic kidney disease. Hum Reprod 14:110–113. doi:10.1093/humrep/14.1.110 PubMedCrossRef Okada H, Fujioka H, Tatsumi N, Fujisawa M, Gohji K, Arakawa S, Kato H, Kobayashi S, Isojima S, Kamidono S (1999) Assisted reproduction for infertile patients with 9 + 0 immotile spermatozoa associated with autosomal dominant polycystic kidney disease. Hum Reprod 14:110–113. doi:10.​1093/​humrep/​14.​1.​110 PubMedCrossRef
Metadata
Title
Male infertility associated with adult dominant polycystic kidney disease: a case series
Authors
Shai Shefi
Jacob Levron
Andrei Nadu
Gil Raviv
Publication date
01-09-2009
Publisher
Springer-Verlag
Published in
Archives of Gynecology and Obstetrics / Issue 3/2009
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-008-0916-9

Other articles of this Issue 3/2009

Archives of Gynecology and Obstetrics 3/2009 Go to the issue