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Archives of Gynecology and Obstetrics

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01-11-2008 | Original Article

The effect of strontium ranelate on serum insulin like growth factor-1 and leptin levels in osteoporotic post-menopausal women: a prospective study

Authors: Ibrahim Gulhan, Sibel Bilgili, Rezzan Gunaydin, Sibel Gulhan, Cemal Posaci

Published in: Archives of Gynecology and Obstetrics | Issue 5/2008

Abstract

Objective

The aim of this study was to investigate the effects of strontium ranelate on insulin like growth factor-1 (IGF-1), leptin and osteocalcin levels in osteoporotic post-menopausal women.

Study design

Thirty-three women were given 2 g/day strontium ranelate for 6 months. Serum IGF-1, leptin and osteocalcin levels were measured before and after the treatment.

Results

Strontium ranelate treatment increased IGF-1 levels significantly (P = 0.02). Leptin and osteocalcin levels did not change significantly before and after the treatment. There was no correlation between basal and 6-months treatment levels of IGF-1 and leptin.

Conclusion

Strontium ranelate increases serum IGF-1 levels in osteoporotic post-menopausal women.

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Title: The effect of strontium ranelate on serum insulin like growth factor-1 and leptin levels in osteoporotic post-menopausal women: a prospective study
Authors: Ibrahim Gulhan
Sibel Bilgili
Rezzan Gunaydin
Sibel Gulhan
Cemal Posaci
Publication date: 01-11-2008
Publisher: Springer-Verlag
Published in: Archives of Gynecology and Obstetrics / Issue 5/2008
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-008-0611-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The effect of strontium ranelate on serum insulin like growth factor-1 and leptin levels in osteoporotic post-menopausal women: a prospective study

Abstract

Objective

Study design

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Study design

Results

Conclusion

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