Top

Archives of Gynecology and Obstetrics

Published in:

01-11-2008 | Original Article

Prevalence of Candida albicans and bacterial vaginosis in asymptomatic pregnant women in South Yorkshire, United Kingdom

Outcome of a prospective study

Authors: A. A. Akinbiyi, Robert Watson, Paul Feyi-Waboso

Published in: Archives of Gynecology and Obstetrics | Issue 5/2008

Abstract

Objective

The aim of the study was to determine the prevalence and age distribution of Candida albicans and bacterial vaginosis in asymptomatic pregnant women.

Method

One thousand and seventy-three (1,073) consecutive women who attended the antenatal clinic at Barnsley District General Hospital, Barnsley, UK, over a 15-month period were studied. Endo-cervical and high vaginal swabs for Candida albicans were obtained.

Results

Sixty-five percent (65%) were in the age group of 21–30 years, and the smallest group was of age 40 years and above. Maternal age of all the women was 25.8 years (SD 5.5) with a range of 33. Prevalence of Candida albicans was 12.5%, and the highest percentage of 65.7% (88 patients) was in the age group of 21–30 years. Prevalence of bacterial vaginosis was 3.54%, with almost 90% among the age group of 21–30 years.

Conclusion

Prevalence of Candida albicans and bacteria vaginosis among asymptomatic pregnant women was 12.5 and 3.54%, respectively.

Hill GB (1993) The microbiology of bacterial vaginosis. Am J Obstet Gynecol 169:450–4PubMed

Akerele J, Abhuimen P, Okonofua F (2002) Prevalence of asymptomatic genital infection among pregnant women in Benin City. Niger Afr J Reprod Health 6(3):93–97, ISSN: 1118-4841CrossRef

Hay PE (1998) Recurrent bacterial vaginosis. Dermatol Clin 16:769–173, xii–xiiiPubMedCrossRef

Amsel R, Totten PA, Spiegel CA, Chen KCS, Eschenbach DA, Holmes KK (1983) Diagnostic criteria and microbial and epidemiologic associations. Am J Med 74:14–22PubMedCrossRef

Hillier SL, Nugent RP, Eschenbach DA, Krohn MA, Gibbs RS, Martin DH et al (1995) Association between bacterial vaginosis and preterm delivery of a low-birth-weight infant. The Vaginal Infections and Prematurity Study Group. N Engl J Med 333:1737–1742PubMedCrossRef

Sobel J (1990) Bacterial vaginosis. Br J Clin Pract Suppl 71:65–69PubMed

Sobel JD (1997) Vaginitis. N Engl J Med 337:1896–1903PubMedCrossRef

Schaaf VM, Perez-Stable EJ, Borchardt K (1990) The limited value of symptoms and signs in the diagnosis of vaginal infections. Arch Intern Med 150:1929–1933PubMedCrossRef

de Oliveira JM, Cruz AS, Fonsecca AF et al (1993) Prevalence of Candida albicans in vaginal flora fluid of asymptomatic Portuguese women. J Reprod Med 38(1):41–42PubMed

10.

Foxman B (1990) The epidemiology of vulvovaginal candidiasis: risk factors. Am J Public Health 80:329–331PubMedCrossRef

11.

Bump RC, Buesching WJ 3rd (1988) Bacterial vaginosis in virginal and sexually active adolescent females: evidence against exclusive sexual transmission. Am J Obstet Gynecol 158:935–939PubMed

12.

Barbone F, Austin H, Louv WC, Alexander WJ (1990) A follow-up study of methods of contraception, sexual activity, and rates of trichomoniasis, candidiasis, and bacterial vaginosis. Am J Obstet Gynecol 163:510–514PubMed

13.

Haukkamaa M, Stranden P, Jousimies-Somer H, Siitonen A (1986) Bacterial flora of the cervix in women using different methods of contraception. Am J Obstet Gynecol 154:520–524PubMed

14.

Hauth JC, MacPherson C, Carey JC, et al (2003) Early pregnancy threshold vaginal pH and Gram stain scores predictive of subsequent preterm birth in asymptomatic women. Am J Obstet Gynecol 188(3):831–835PubMedCrossRef

15.

Simhan HN, Caritis SN, Krohn MA et al (2003) Elevated vaginal pH and neutrophils are strongly associated with early spontaneous preterm birth. Am J Obstet Gynecol 189:1150–1154PubMedCrossRef

16.

Yudin MH, Landers DV, Meyn L et al (2003) Clinical and cervical cytokines response to treatment with oral or vaginal metronidazole for bacterial vaginosis during pregnancy: a randomized trial. Obstet Gynecol 102:527PubMedCrossRef

17.

Sobel JD, Faro S, Force RW, Foxman B, Ledger WJ, Nyirjesy PR et al (1998) Vulvovaginal candidiasis: epidemiologic, diagnostic, and therapeutic considerations. Am J Obstet Gynecol 178:203–211PubMedCrossRef

18.

Hay PE, Lamont RF, Taylor-Robinson D, Morgan DJ, Ison C, Pearson J (1994) Abnormal bacterial colonisation of the genital tract and subsequent preterm delivery and late miscarriage. BMJ 308:295–298PubMed

19.

Mazzulli T, Simor AE, Low DE (1990) Reproducibility of interpretation of Gram-stained vaginal smears for the diagnosis of bacterial vaginosis. J Clin Microbiol 28:1506–1508PubMed

20.

Gibbs RS (2001) The relationship between infections and adverse pregnancy outcomes: an overview. Ann Periodontol 6(1):153–163PubMedCrossRef

21.

Carey JC, Klebanoff MA (2001) Bacterial vaginosis and other asymptomatic vaginal infections in pregnancy. Curr Women’s Health Rep 1(1):14–19

22.

Locksmith G, Duff P (2001) Infection, antibiotics and preterm delivery. Semin Perinatol 25(5):295–309PubMedCrossRef

23.

Cotch MF, Hillier SL, Gibbs RS, Eschenbach DA (1998) Epidemiology and outcomes associated with moderate to heavy Candida colonization during pregnancy. Vaginal Infections and Prematurity Study Group. Am J Obstet Gynecol 178:374–380PubMedCrossRef

24.

Thomason JL, Gelbart SM, Anderson RJ, Walt AK, Osypowski PJ, Broekhuizen FF (1990) Statistical evaluation of diagnostic criteria for bacterial vaginosis. Am J Obstet Gynecol 162:155–160PubMed

25.

Krohn MA, Hillier SL, Eschenbach DA (1989) Comparison of methods for diagnosing bacterial vaginosis among pregnant women. J Clin Microbiol 27:1266–1271PubMed

Title: Prevalence of Candida albicans and bacterial vaginosis in asymptomatic pregnant women in South Yorkshire, United Kingdom
Outcome of a prospective study
Authors: A. A. Akinbiyi
Robert Watson
Paul Feyi-Waboso
Publication date: 01-11-2008
Publisher: Springer-Verlag
Published in: Archives of Gynecology and Obstetrics / Issue 5/2008
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-008-0593-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Prevalence of Candida albicans and bacterial vaginosis in asymptomatic pregnant women in South Yorkshire, United Kingdom

Outcome of a prospective study

Abstract

Objective

Method

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Method

Results

Conclusion

Please log in to get access to this content

Other articles of this Issue 5/2008

Re-laparotomy after cesarean section: operative complications in surgical delivery

Rare metastases of recurrent cervical cancer to the pericardium and abdominal muscle

Prenatal ultrasonographic features of persistent urogenital sinus with hydrometrocolpos and ascites

Adenoid cystic carcinoma of the Bartholin’s gland: a rare tumor unmarked by persistent vulvar pain in a postmenopausal women

Anesthesia machine as a cause of intraoperative “code red” in the labor and delivery suite

Face and brow presentation in northern Jordan, over a decade of experience