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Published in: Archives of Gynecology and Obstetrics 3/2007

01-03-2007 | Original Article

Menopausal symptoms and associated risk factors among postmenopausal women screened for the metabolic syndrome

Authors: P. Chedraui, L. Hidalgo, D. Chavez, N. Morocho, M. Alvarado, A. Huc

Published in: Archives of Gynecology and Obstetrics | Issue 3/2007

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Abstract

Background

Although the frequency of menopausal symptoms may vary according to the studied population, in general severe intensity has been related to lower quality of life.

Objective

To assess the frequency of menopausal symptoms and involved risk factors in an Ecuadorian postmenopausal population.

Methods

Postmenopausal women that participated in a metabolic syndrome screening program were interviewed with the Menopause-specific quality of life questionnaire (MENQOL) in order to determine the most frequently presenting menopausal symptoms and correlate these symptoms with socio-demographic data and the main results of the screening program.

Results

Three hundred and twenty-five postmenopausal women (= 325) were surveyed with the MENQOL. Mean age of participants was 55.9 ± 8.1 years (median: 54 years). The most frequently presenting symptoms were: hot flushes (53.3%), sweating (49.2%), poor memory (80.6%), feeling depressed (67.4%), aching in muscles and joints (84%), drying of their skin (85.5%), avoiding intimacy (76.2%) and change in their sexual desire (76.5%). Multivariate analysis determined that abdominal obesity was a significant risk factor for presenting hot flushes, depression and muscle and joint pain. High triglyceride levels were associated to higher rates of sweating and depression. While women with basal hyperglycemia were associated to dry skin and changes in sexual desire in a higher proportion, those who were older and with more years of menopause onset were related less frequently to vasomotor symptoms. Older age was also significantly associated in a higher rate to dry skin.

Conclusion

In this postmenopausal Ecuadorian population, the frequency of menopausal symptoms, as assessed with the MENQOL, was found to be relatively similar to other Latin and non-Latin American populations and associated to age, hormonal status and related metabolic conditions.
Literature
1.
go back to reference Blumel JE, Brandt A, Tacla X (1992) Symptomatic profile of the climacteric female clinical experience. Rev Med Chil 120:1017–1021PubMed Blumel JE, Brandt A, Tacla X (1992) Symptomatic profile of the climacteric female clinical experience. Rev Med Chil 120:1017–1021PubMed
2.
go back to reference Blumel JE, Castelo-Branco C, Binfa L, Gramegna G, Tacla X, Aracena B, Cumsille MA, Sanjuan A (2000) Quality of life after the menopause: a population study. Maturitas 34:17–23PubMedCrossRef Blumel JE, Castelo-Branco C, Binfa L, Gramegna G, Tacla X, Aracena B, Cumsille MA, Sanjuan A (2000) Quality of life after the menopause: a population study. Maturitas 34:17–23PubMedCrossRef
3.
go back to reference Blumel JE, Castelo-Branco C, Roncagliolo ME, Binfa L, Sarra S (2003) Cardiovascular risk factors in a cohort of middle-aged women. Rev Med Chil 131:381–389PubMed Blumel JE, Castelo-Branco C, Roncagliolo ME, Binfa L, Sarra S (2003) Cardiovascular risk factors in a cohort of middle-aged women. Rev Med Chil 131:381–389PubMed
4.
go back to reference Blumel JE, Chedraui P, Calle A, et al (2006) Age of menopause presentation in Latin America. Menopause 13:706–712PubMedCrossRef Blumel JE, Chedraui P, Calle A, et al (2006) Age of menopause presentation in Latin America. Menopause 13:706–712PubMedCrossRef
5.
go back to reference Buckler H (2005) The menopause transition: endocrine changes and clinical symptoms. J Br Menopause Soc 11:61–65PubMedCrossRef Buckler H (2005) The menopause transition: endocrine changes and clinical symptoms. J Br Menopause Soc 11:61–65PubMedCrossRef
6.
go back to reference Burger HG, Dudley EC, Robertson DM, Dennerstein L (2002) Hormonal changes in the menopause transition. Recent Prog Horm Res 57:257–275PubMedCrossRef Burger HG, Dudley EC, Robertson DM, Dennerstein L (2002) Hormonal changes in the menopause transition. Recent Prog Horm Res 57:257–275PubMedCrossRef
7.
go back to reference Carr MC (2003) The emergence of the metabolic syndrome with menopause. J Clin Endocrinol Metab 88:2404–2411PubMedCrossRef Carr MC (2003) The emergence of the metabolic syndrome with menopause. J Clin Endocrinol Metab 88:2404–2411PubMedCrossRef
8.
go back to reference Castelo-Branco C, Blumel JE, Araya H, Riquelme R, Castro G, Haya J, et al (2003) Prevalence of sexual dysfunction in a cohort of middle-aged women: influences of menopause and hormone replacement therapy. J Obstet Gynaecol 23:426–430PubMedCrossRef Castelo-Branco C, Blumel JE, Araya H, Riquelme R, Castro G, Haya J, et al (2003) Prevalence of sexual dysfunction in a cohort of middle-aged women: influences of menopause and hormone replacement therapy. J Obstet Gynaecol 23:426–430PubMedCrossRef
9.
go back to reference Castelo-Branco C, Blumel JE, Roncagliolo ME, Haya J, Bolf D, Binfa L, Tacla X, Colondron M (2003) Age, menopause and hormone replacement therapy influences on cardiovascular risk factors in a cohort of middle-aged Chilean women. Maturitas 45:205–212PubMedCrossRef Castelo-Branco C, Blumel JE, Roncagliolo ME, Haya J, Bolf D, Binfa L, Tacla X, Colondron M (2003) Age, menopause and hormone replacement therapy influences on cardiovascular risk factors in a cohort of middle-aged Chilean women. Maturitas 45:205–212PubMedCrossRef
10.
go back to reference Chedraui P, Hidalgo L, Morocho N, Alvarado M, Chavez D, Huc A (2005) Metabolic syndrome in postmenopausal Ecuadorian women. Climacteric 8:S94 Chedraui P, Hidalgo L, Morocho N, Alvarado M, Chavez D, Huc A (2005) Metabolic syndrome in postmenopausal Ecuadorian women. Climacteric 8:S94
11.
go back to reference Chedraui P, Hidalgo L, Chavez D, Morocho N, Alvarado, Huc A (in press) Quality of life among postmenopausal Ecuadorian women participating in a metabolic syndrome screening program. Maturitas Chedraui P, Hidalgo L, Chavez D, Morocho N, Alvarado, Huc A (in press) Quality of life among postmenopausal Ecuadorian women participating in a metabolic syndrome screening program. Maturitas
12.
go back to reference den Tonkelaar I, Seidell JC, van Noord PA (1996) Obesity and fat distribution in relation to hot flashes in Dutch women from the DOM-project. Maturitas 23:301–305CrossRef den Tonkelaar I, Seidell JC, van Noord PA (1996) Obesity and fat distribution in relation to hot flashes in Dutch women from the DOM-project. Maturitas 23:301–305CrossRef
13.
go back to reference Expert Panel on Detection, Evaluation, Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) (2001) Executive summary of the third report of the National Cholesterol Education Program (NCEP). J Am Med Assoc 285:2486–2497 Expert Panel on Detection, Evaluation, Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) (2001) Executive summary of the third report of the National Cholesterol Education Program (NCEP). J Am Med Assoc 285:2486–2497
14.
go back to reference Hidalgo LA, Chedraui PA, Schwager G, Chavez P (2003) Lumbar spine bone mineral density in climacteric Ecuadorian women. Rev Ecuat Ginecol Obstet 10:288–291 Hidalgo LA, Chedraui PA, Schwager G, Chavez P (2003) Lumbar spine bone mineral density in climacteric Ecuadorian women. Rev Ecuat Ginecol Obstet 10:288–291
15.
go back to reference Hidalgo LA, Chedraui PA, Naveda C (2004) Quantitative ultrasound at radius and its correlation with serum osteocalcin levels in climacteric women. Rev Ecuat Ginecol Obstet 11:213–217 Hidalgo LA, Chedraui PA, Naveda C (2004) Quantitative ultrasound at radius and its correlation with serum osteocalcin levels in climacteric women. Rev Ecuat Ginecol Obstet 11:213–217
16.
go back to reference Hidalgo LA, Chedraui PA, Chavez MJ (2005) Obstetrical and neonatal outcome in young adolescents of low socio-economic status: a case control study. Arch Gynecol Obstet 271:207–211PubMedCrossRef Hidalgo LA, Chedraui PA, Chavez MJ (2005) Obstetrical and neonatal outcome in young adolescents of low socio-economic status: a case control study. Arch Gynecol Obstet 271:207–211PubMedCrossRef
17.
go back to reference Hilditch JR, Lewis J, Peter A, van Maris B, Ross A, Franssen E, Guyatt GH, Norton PG, Dunn E (1996) A menopause-specific quality of life questionnaire: development and psychometric properties. Maturitas 24:161–75PubMed Hilditch JR, Lewis J, Peter A, van Maris B, Ross A, Franssen E, Guyatt GH, Norton PG, Dunn E (1996) A menopause-specific quality of life questionnaire: development and psychometric properties. Maturitas 24:161–75PubMed
18.
go back to reference Jasienska G, Ziomkiewicz A, Gorkiewicz M, Pajak A (2005) Body mass, depressive symptoms and menopausal status: an examination of the “Jolly Fat” hypothesis. Womens Health Issues 15:145–151PubMedCrossRef Jasienska G, Ziomkiewicz A, Gorkiewicz M, Pajak A (2005) Body mass, depressive symptoms and menopausal status: an examination of the “Jolly Fat” hypothesis. Womens Health Issues 15:145–151PubMedCrossRef
19.
go back to reference Kwawukume EY, Ghosh TS, Wilson JB (1993) Menopausal age of Ghanaian women. Int J Gynaecol Obstet 40:151–155PubMedCrossRef Kwawukume EY, Ghosh TS, Wilson JB (1993) Menopausal age of Ghanaian women. Int J Gynaecol Obstet 40:151–155PubMedCrossRef
20.
go back to reference Lebrun CE, van der Schouw YT, de Jong FH, Pols HA, Grobbee DE, Lamberts SW (2006) Relations between body composition, functional and hormonal parameters and quality of life in healthy postmenopausal women. Maturitas 55:82–92PubMedCrossRef Lebrun CE, van der Schouw YT, de Jong FH, Pols HA, Grobbee DE, Lamberts SW (2006) Relations between body composition, functional and hormonal parameters and quality of life in healthy postmenopausal women. Maturitas 55:82–92PubMedCrossRef
21.
go back to reference Li C, Samsioe G, Borgfeldt C, Lidfeldt J, Agardh CD, Nerbrand C (2003) Menopause-related symptoms: what are the background factors? A prospective population-based cohort study of Swedish women (The Women’s Health in Lund Area Study). Am J Obstet Gynecol 189:1646–1653PubMedCrossRef Li C, Samsioe G, Borgfeldt C, Lidfeldt J, Agardh CD, Nerbrand C (2003) Menopause-related symptoms: what are the background factors? A prospective population-based cohort study of Swedish women (The Women’s Health in Lund Area Study). Am J Obstet Gynecol 189:1646–1653PubMedCrossRef
22.
go back to reference Malacara JM, Canto de Cetina T, Bassol S, Gonzalez N, Cacique L, Vera-Ramirez ML, Nava LE (2002) Symptoms at pre- and postmenopause in rural and urban women from three States of Mexico. Maturitas 43:11–19PubMedCrossRef Malacara JM, Canto de Cetina T, Bassol S, Gonzalez N, Cacique L, Vera-Ramirez ML, Nava LE (2002) Symptoms at pre- and postmenopause in rural and urban women from three States of Mexico. Maturitas 43:11–19PubMedCrossRef
23.
go back to reference Miller AM, Wilbur J, Chandler PJ, Sorokin O (2003) Cardiovascular disease risk factors and menopausal status in midlife women from the former Soviet Union. Women Health 38:19–36PubMedCrossRef Miller AM, Wilbur J, Chandler PJ, Sorokin O (2003) Cardiovascular disease risk factors and menopausal status in midlife women from the former Soviet Union. Women Health 38:19–36PubMedCrossRef
24.
go back to reference Nadel I, Cypryk K, Pertynski T, Sobczuk A, Stetkiewicz T (2001) Studies on the incidence and clinical significance of the metabolic syndrome in postmenopausal women in Lodz region. Pol Arch Med Wewn 106:823–828PubMed Nadel I, Cypryk K, Pertynski T, Sobczuk A, Stetkiewicz T (2001) Studies on the incidence and clinical significance of the metabolic syndrome in postmenopausal women in Lodz region. Pol Arch Med Wewn 106:823–828PubMed
25.
go back to reference Nedstrand E, Pertl J, Hammar M (1996) Climacteric symptoms in a postmenopausal Czech population. Maturitas 23:85–89PubMedCrossRef Nedstrand E, Pertl J, Hammar M (1996) Climacteric symptoms in a postmenopausal Czech population. Maturitas 23:85–89PubMedCrossRef
26.
go back to reference Pastore LM, Carter RA, Hulka BS, Wells E (2004) Self-reported urogenital symptoms in postmenopausal women: Women’s Health Initiative. Maturitas 49:292–303PubMedCrossRef Pastore LM, Carter RA, Hulka BS, Wells E (2004) Self-reported urogenital symptoms in postmenopausal women: Women’s Health Initiative. Maturitas 49:292–303PubMedCrossRef
27.
go back to reference Pedro AO, Pinto-Neto AM, Costa-Paiva LH, Osis MJ, Hardy EE (2003) Climacteric syndrome: a population-based study in Campinas, SP, Brazil. Rev Saude Publica 37:735–42PubMedCrossRef Pedro AO, Pinto-Neto AM, Costa-Paiva LH, Osis MJ, Hardy EE (2003) Climacteric syndrome: a population-based study in Campinas, SP, Brazil. Rev Saude Publica 37:735–42PubMedCrossRef
28.
go back to reference Raikkonen K, Matthews KA, Kuller LH (1999) Anthropometric and psychosocial determinants of visceral obesity in healthy postmenopausal women. Int J Obes Relat Metab Disord 23:775–782PubMedCrossRef Raikkonen K, Matthews KA, Kuller LH (1999) Anthropometric and psychosocial determinants of visceral obesity in healthy postmenopausal women. Int J Obes Relat Metab Disord 23:775–782PubMedCrossRef
29.
go back to reference Schwingl PJ, Hulka BS, Harlow SD (1994) Risk factors for menopausal hot flashes. Obstet Gynecol 84:29–34PubMed Schwingl PJ, Hulka BS, Harlow SD (1994) Risk factors for menopausal hot flashes. Obstet Gynecol 84:29–34PubMed
30.
go back to reference Sierra B, Hidalgo LA, Chedraui PA (2005) Measuring climacteric symptoms in an Ecuadorian population with the Greene Climacteric Scale. Maturitas 51:236–245PubMedCrossRef Sierra B, Hidalgo LA, Chedraui PA (2005) Measuring climacteric symptoms in an Ecuadorian population with the Greene Climacteric Scale. Maturitas 51:236–245PubMedCrossRef
31.
go back to reference Spencer CP, Godsland IF, Stevenson JC (1997) Is there a menopausal metabolic syndrome? Gynecol Endocrinol 11:341–355PubMedCrossRef Spencer CP, Godsland IF, Stevenson JC (1997) Is there a menopausal metabolic syndrome? Gynecol Endocrinol 11:341–355PubMedCrossRef
32.
go back to reference Thunell L, Stadberg E, Milsom I, Mattsson LA (2004) A longitudinal population study of climacteric symptoms and their treatment in a random sample of Swedish women. Climacteric 7:357–365PubMedCrossRef Thunell L, Stadberg E, Milsom I, Mattsson LA (2004) A longitudinal population study of climacteric symptoms and their treatment in a random sample of Swedish women. Climacteric 7:357–365PubMedCrossRef
33.
go back to reference Whiteman MK, Staropoli CA, Langenberg PW, McCarter RJ, Kjerulff KH, Flaws JA (2003) Smoking, body mass, and hot flashes in midlife women. Obstet Gynecol 101:264–272PubMedCrossRef Whiteman MK, Staropoli CA, Langenberg PW, McCarter RJ, Kjerulff KH, Flaws JA (2003) Smoking, body mass, and hot flashes in midlife women. Obstet Gynecol 101:264–272PubMedCrossRef
34.
go back to reference Wilbur J, Miller AM, Montgomery A, Chandler P (1998) Sociodemographic characteristics, biological factors, and symptom reporting in midlife women. Menopause 5:43–51PubMedCrossRef Wilbur J, Miller AM, Montgomery A, Chandler P (1998) Sociodemographic characteristics, biological factors, and symptom reporting in midlife women. Menopause 5:43–51PubMedCrossRef
35.
go back to reference Zollner YF, Acquadro C, Schaefer M (2005) Literature review of instruments to assess health-related quality of life during and after menopause. Qual Life Res 14:309–327PubMedCrossRef Zollner YF, Acquadro C, Schaefer M (2005) Literature review of instruments to assess health-related quality of life during and after menopause. Qual Life Res 14:309–327PubMedCrossRef
Metadata
Title
Menopausal symptoms and associated risk factors among postmenopausal women screened for the metabolic syndrome
Authors
P. Chedraui
L. Hidalgo
D. Chavez
N. Morocho
M. Alvarado
A. Huc
Publication date
01-03-2007
Publisher
Springer-Verlag
Published in
Archives of Gynecology and Obstetrics / Issue 3/2007
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-006-0239-7

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