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Published in: Archives of Dermatological Research 9/2014

01-11-2014 | Original Paper

Keloid incidence in Asian people and its comorbidity with other fibrosis-related diseases: a nationwide population-based study

Authors: Lei-Ming Sun, Kuo-Hsien Wang, Yuan-Chii G. Lee

Published in: Archives of Dermatological Research | Issue 9/2014

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Abstract

Keloids is a fibroproliferative disease. The incidence of keloids among Asians has not been thoroughly studied. The objective of this study is to determine the incidence of keloids in Taiwan, which mainly consists of ethnic Chinese. Furthermore, we want to determine the comorbidity rate of other fibrosis-related diseases among keloid patients. This study was based on the National Health Insurance Research Database, which contains the data of 1 million randomly selected patients. Multivariate logistic regression analyses were employed to estimate the relative odds of keloids as a function of fibrosis-related diseases. The annual keloid incidence rate in Taiwan was 0.15 % for the general population. With a 1.33 ratio, women outnumbered men. Women with uterine leiomyoma have a 2.25-fold greater risk of keloids, compared with women without leiomyoma. We concluded that keloid incidence in Taiwan is approximately 0.15 %. Women with leiomyoma have a greater risk of keloids, this implicates that both diseases share a common etiopathological pathway.
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Metadata
Title
Keloid incidence in Asian people and its comorbidity with other fibrosis-related diseases: a nationwide population-based study
Authors
Lei-Ming Sun
Kuo-Hsien Wang
Yuan-Chii G. Lee
Publication date
01-11-2014
Publisher
Springer Berlin Heidelberg
Published in
Archives of Dermatological Research / Issue 9/2014
Print ISSN: 0340-3696
Electronic ISSN: 1432-069X
DOI
https://doi.org/10.1007/s00403-014-1491-5

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