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01-12-2014 | Concise Communication

Innate immune cells express IL-17A/F in acute generalized exanthematous pustulosis and generalized pustular psoriasis

Authors: M. Kakeda, Christoph Schlapbach, G. Danelon, M. M. Tang, V. Cecchinato, N. Yawalkar, M. Uguccioni

Published in: Archives of Dermatological Research | Issue 10/2014

Abstract

Acute generalized exanthematous pustulosis (AGEP) and generalized pustular psoriasis (GPP) are rare pustular skin disorders with systemic involvement. IL-17A/F is a proinflammatory cytokine involved in various neutrophilic inflammatory disorders. Here we show that IL-17A/F is highly expressed by innate immune cells such as neutrophils and mast cells in both AGEP and GPP.

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Title: Innate immune cells express IL-17A/F in acute generalized exanthematous pustulosis and generalized pustular psoriasis
Authors: M. Kakeda
Christoph Schlapbach
G. Danelon
M. M. Tang
V. Cecchinato
N. Yawalkar
M. Uguccioni
Publication date: 01-12-2014
Publisher: Springer Berlin Heidelberg
Published in: Archives of Dermatological Research / Issue 10/2014
Print ISSN: 0340-3696
Electronic ISSN: 1432-069X
DOI: https://doi.org/10.1007/s00403-014-1488-0

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Innate immune cells express IL-17A/F in acute generalized exanthematous pustulosis and generalized pustular psoriasis

Abstract

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Abstract

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