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Published in: Archives of Orthopaedic and Trauma Surgery 12/2023

27-07-2023 | Antibiotic | Hip Arthroplasty

Analysis of the effects of intraoperative warming devices on surgical site infection in elective hip arthroplasty using a large nationwide database

Authors: Seung Hoon Kim, Suk-Yong Jang, Yonghan Cha, Bo-Yeon Kim, Hyo-Jung Lee, Gui-Ok Kim

Published in: Archives of Orthopaedic and Trauma Surgery | Issue 12/2023

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Abstract

Introduction

The aim of our study is to analyze the association of usage and type of warming device with the risk of surgical site infection (SSI) in patients who underwent hip arthroplasty, and to analyze the factors that increase the risk of SSI if the warming device is not used.

Materials and methods

This retrospective cross-sectional study identified subjects from data of “Evaluation of the Appropriate Use of Prophylactic Antibiotics”. Included patients were defined as those who underwent elective unilateral hip hemiarthroplasty or total hip arthroplasty (THA). Patients were classified into no intraoperative warming device, forced air warming devices, and devices using conduction. Multiple logistic regression analysis was conducted to estimate adjusted odds ratios (aORs) and 95% confidence intervals (CIs) to assess the association between warming devices and SSI.

Results

A total of 3945 patients met the inclusion criteria. Compared to those who received an intraoperative warming device, the odds of developing SSI were 1.9 times higher in those who did not receive intraoperative warming devices (aOR 1.9; 95% CI 1.1–3.6). The risk of SSI was 2.2 times higher with forced air warming devices compared to devices using conduction but this difference was not statistically significant (aOR 2.2; 95% CI 0.7–6.8). The risk of SSI increased in males (aOR 2.8; 95% CI 1.1–7.2), in patients under 70 years of age (aOR 4.4; 95% CI 1.6–10.4), in patients with a Charlson`s comorbidity index of 2 or higher (aOR 3.3; 95% CI 1.3–8.7), and in patients who underwent THA (aOR 3.8; 95% CI 1.7–8.3) when intraoperative warming devices were not used.

Conclusions

The use of intraoperative active warming devices is highly recommended to prevent SSI during elective hip arthroplasty. In particular, male patients younger than 70 years, those with a high CCI, and those undergoing THA are at significantly increased risk of SSI if intraoperative active warming devices are not used. Intraoperative warming device using conduction is likely superior to forced air warming device, but further studies are needed to confirm this.
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Literature
1.
go back to reference Aalirezaie A, Akkaya M, Barnes CL et al (2019) General assembly, prevention, operating room environment: proceeding of international consensus on orthopedic infections. J Arthroplasty 34(2s):S105-s115CrossRefPubMed Aalirezaie A, Akkaya M, Barnes CL et al (2019) General assembly, prevention, operating room environment: proceeding of international consensus on orthopedic infections. J Arthroplasty 34(2s):S105-s115CrossRefPubMed
2.
3.
go back to reference Badia JM, Casey AL, Petrosillo N, Hudson PM, Mitchell SA, Crosby C (2017) Impact of surgical site infection on healthcare costs and patient outcomes: a systematic review in six European countries. J Hosp Infect 96(1):1–15CrossRefPubMed Badia JM, Casey AL, Petrosillo N, Hudson PM, Mitchell SA, Crosby C (2017) Impact of surgical site infection on healthcare costs and patient outcomes: a systematic review in six European countries. J Hosp Infect 96(1):1–15CrossRefPubMed
4.
go back to reference Beery TA (2003) Sex differences in infection and sepsis. Crit Care Nurs Clin North Am 15(1):55–62CrossRefPubMed Beery TA (2003) Sex differences in infection and sepsis. Crit Care Nurs Clin North Am 15(1):55–62CrossRefPubMed
5.
go back to reference Beilin B, Shavit Y, Razumovsky J, Wolloch Y, Zeidel A, Bessler H (1998) Effects of mild perioperative hypothermia on cellular immune responses. Anesthesiology 89(5):1133–1140CrossRefPubMed Beilin B, Shavit Y, Razumovsky J, Wolloch Y, Zeidel A, Bessler H (1998) Effects of mild perioperative hypothermia on cellular immune responses. Anesthesiology 89(5):1133–1140CrossRefPubMed
6.
go back to reference Brand JM, Frohn C, Luhm J, Kirchner H, Schmucker P (2003) Early alterations in the number of circulating lymphocyte subpopulations and enhanced proinflammatory immune response during opioid-based general anesthesia. Shock 20(3):213–217CrossRefPubMed Brand JM, Frohn C, Luhm J, Kirchner H, Schmucker P (2003) Early alterations in the number of circulating lymphocyte subpopulations and enhanced proinflammatory immune response during opioid-based general anesthesia. Shock 20(3):213–217CrossRefPubMed
7.
go back to reference DeSouza CA, Clevenger CM, Greiner JJ et al (2002) Evidence for agonist-specific endothelial vasodilator dysfunction with ageing in healthy humans. J Physiol 542(Pt 1):255–262CrossRefPubMedPubMedCentral DeSouza CA, Clevenger CM, Greiner JJ et al (2002) Evidence for agonist-specific endothelial vasodilator dysfunction with ageing in healthy humans. J Physiol 542(Pt 1):255–262CrossRefPubMedPubMedCentral
8.
go back to reference Frisch NB, Pepper AM, Jildeh TR, Shaw J, Guthrie T, Silverton C (2016) Intraoperative hypothermia during surgical fixation of hip fractures. Orthopedics 39(6):e1170–e1177CrossRefPubMed Frisch NB, Pepper AM, Jildeh TR, Shaw J, Guthrie T, Silverton C (2016) Intraoperative hypothermia during surgical fixation of hip fractures. Orthopedics 39(6):e1170–e1177CrossRefPubMed
9.
go back to reference Kellam MD, Dieckmann LS, Austin PN (2013) Forced-air warming devices and the risk of surgical site infections. Aorn J 98(4):354–366 (quiz 367–359)CrossRefPubMed Kellam MD, Dieckmann LS, Austin PN (2013) Forced-air warming devices and the risk of surgical site infections. Aorn J 98(4):354–366 (quiz 367–359)CrossRefPubMed
10.
go back to reference Koc BB, Schotanus MGM, Kollenburg J, Janssen MJA, Tijssen F, Jansen EJP (2017) Effectiveness of early warming with self-warming blankets on postoperative hypothermia in total hip and knee arthroplasty. Orthop Nurs 36(5):356–360CrossRefPubMed Koc BB, Schotanus MGM, Kollenburg J, Janssen MJA, Tijssen F, Jansen EJP (2017) Effectiveness of early warming with self-warming blankets on postoperative hypothermia in total hip and knee arthroplasty. Orthop Nurs 36(5):356–360CrossRefPubMed
11.
go back to reference Kong L, Cao J, Zhang Y, Ding W, Shen Y (2017) Risk factors for periprosthetic joint infection following primary total hip or knee arthroplasty: a meta-analysis. Int Wound J 14(3):529–536CrossRefPubMed Kong L, Cao J, Zhang Y, Ding W, Shen Y (2017) Risk factors for periprosthetic joint infection following primary total hip or knee arthroplasty: a meta-analysis. Int Wound J 14(3):529–536CrossRefPubMed
12.
go back to reference Kümin M, Deery J, Turney S et al (2019) Reducing Implant Infection in Orthopaedics (RIIiO): results of a pilot study comparing the influence of forced air and resistive fabric warming technologies on postoperative infections following orthopaedic implant surgery. J Hosp Infect 103(4):412–419CrossRefPubMed Kümin M, Deery J, Turney S et al (2019) Reducing Implant Infection in Orthopaedics (RIIiO): results of a pilot study comparing the influence of forced air and resistive fabric warming technologies on postoperative infections following orthopaedic implant surgery. J Hosp Infect 103(4):412–419CrossRefPubMed
13.
go back to reference Kümin M, Jones CI, Woods A et al (2021) Resistant fabric warming is a viable alternative to forced-air warming to prevent inadvertent perioperative hypothermia during hemiarthroplasty in the elderly. J Hosp Infect 118:79–86CrossRefPubMed Kümin M, Jones CI, Woods A et al (2021) Resistant fabric warming is a viable alternative to forced-air warming to prevent inadvertent perioperative hypothermia during hemiarthroplasty in the elderly. J Hosp Infect 118:79–86CrossRefPubMed
14.
go back to reference Kunutsor SK, Whitehouse MR, Blom AW, Beswick AD (2016) Patient-related risk factors for periprosthetic joint infection after total joint arthroplasty: a systematic review and meta-analysis. PLoS ONE 11(3):e0150866CrossRefPubMedPubMedCentral Kunutsor SK, Whitehouse MR, Blom AW, Beswick AD (2016) Patient-related risk factors for periprosthetic joint infection after total joint arthroplasty: a systematic review and meta-analysis. PLoS ONE 11(3):e0150866CrossRefPubMedPubMedCentral
15.
go back to reference Legg AJ, Cannon T, Hamer AJ (2012) Do forced air patient-warming devices disrupt unidirectional downward airflow? J Bone Joint Surg Br 94(2):254–256CrossRefPubMed Legg AJ, Cannon T, Hamer AJ (2012) Do forced air patient-warming devices disrupt unidirectional downward airflow? J Bone Joint Surg Br 94(2):254–256CrossRefPubMed
16.
go back to reference Leijtens B, Koëter M, Kremers K, Koëter S (2013) High incidence of postoperative hypothermia in total knee and total hip arthroplasty: a prospective observational study. J Arthroplasty 28(6):895–898CrossRefPubMed Leijtens B, Koëter M, Kremers K, Koëter S (2013) High incidence of postoperative hypothermia in total knee and total hip arthroplasty: a prospective observational study. J Arthroplasty 28(6):895–898CrossRefPubMed
17.
go back to reference Lenhardt R, Marker E, Goll V et al (1997) Mild intraoperative hypothermia prolongs postanesthetic recovery. Anesthesiology 87(6):1318–1323CrossRefPubMed Lenhardt R, Marker E, Goll V et al (1997) Mild intraoperative hypothermia prolongs postanesthetic recovery. Anesthesiology 87(6):1318–1323CrossRefPubMed
18.
go back to reference Lewis DP, Wæver D, Thorninger R, Donnelly WJ (2019) Hemiarthroplasty vs total hip arthroplasty for the management of displaced neck of femur fractures: a systematic review and meta-analysis. J Arthroplasty 34(8):1837-1843.e1832CrossRefPubMed Lewis DP, Wæver D, Thorninger R, Donnelly WJ (2019) Hemiarthroplasty vs total hip arthroplasty for the management of displaced neck of femur fractures: a systematic review and meta-analysis. J Arthroplasty 34(8):1837-1843.e1832CrossRefPubMed
19.
go back to reference Li X, Luo J (2021) Hemiarthroplasty compared to total hip arthroplasty for the treatment of femoral neck fractures: a systematic review and meta-analysis. J Orthop Surg Res 16(1):172CrossRefPubMed Li X, Luo J (2021) Hemiarthroplasty compared to total hip arthroplasty for the treatment of femoral neck fractures: a systematic review and meta-analysis. J Orthop Surg Res 16(1):172CrossRefPubMed
20.
go back to reference Madrid E, Urrútia G, Roqué I Figuls M et al (2016) Active body surface warming systems for preventing complications caused by inadvertent perioperative hypothermia in adults. Cochrane Database Syst Rev 4(4):Cd009016PubMed Madrid E, Urrútia G, Roqué I Figuls M et al (2016) Active body surface warming systems for preventing complications caused by inadvertent perioperative hypothermia in adults. Cochrane Database Syst Rev 4(4):Cd009016PubMed
21.
go back to reference Mahoney CB, Odom J (1999) Maintaining intraoperative normothermia: a meta-analysis of outcomes with costs. Aana J 67(2):155–163PubMed Mahoney CB, Odom J (1999) Maintaining intraoperative normothermia: a meta-analysis of outcomes with costs. Aana J 67(2):155–163PubMed
22.
go back to reference McGovern PD, Albrecht M, Belani KG et al (2011) Forced-air warming and ultra-clean ventilation do not mix: an investigation of theatre ventilation, patient warming and joint replacement infection in orthopaedics. J Bone Joint Surg Br 93(11):1537–1544CrossRefPubMed McGovern PD, Albrecht M, Belani KG et al (2011) Forced-air warming and ultra-clean ventilation do not mix: an investigation of theatre ventilation, patient warming and joint replacement infection in orthopaedics. J Bone Joint Surg Br 93(11):1537–1544CrossRefPubMed
23.
go back to reference Memarzadeh F (2010) Active warming systems to maintain perioperative normothermia in hip replacement surgery. J Hosp Infect 75(4):332–333CrossRefPubMed Memarzadeh F (2010) Active warming systems to maintain perioperative normothermia in hip replacement surgery. J Hosp Infect 75(4):332–333CrossRefPubMed
24.
go back to reference Moretti B, Larocca AM, Napoli C et al (2009) Active warming systems to maintain perioperative normothermia in hip replacement surgery: a therapeutic aid or a vector of infection? J Hosp Infect 73(1):58–63CrossRefPubMed Moretti B, Larocca AM, Napoli C et al (2009) Active warming systems to maintain perioperative normothermia in hip replacement surgery: a therapeutic aid or a vector of infection? J Hosp Infect 73(1):58–63CrossRefPubMed
25.
go back to reference Parvizi J, Tan TL, Goswami K et al (2018) The 2018 definition of periprosthetic hip and knee infection: an evidence-based and validated criteria. J Arthroplasty 33(5):1309-1314.e1302CrossRefPubMed Parvizi J, Tan TL, Goswami K et al (2018) The 2018 definition of periprosthetic hip and knee infection: an evidence-based and validated criteria. J Arthroplasty 33(5):1309-1314.e1302CrossRefPubMed
26.
go back to reference Quan H, Li B, Couris CM et al (2011) Updating and validating the Charlson comorbidity index and score for risk adjustment in hospital discharge abstracts using data from 6 countries. Am J Epidemiol 173(6):676–682CrossRefPubMed Quan H, Li B, Couris CM et al (2011) Updating and validating the Charlson comorbidity index and score for risk adjustment in hospital discharge abstracts using data from 6 countries. Am J Epidemiol 173(6):676–682CrossRefPubMed
27.
go back to reference Rasouli MR, Restrepo C, Maltenfort MG, Purtill JJ, Parvizi J (2014) Risk factors for surgical site infection following total joint arthroplasty. J Bone Joint Surg Am 96(18):e158CrossRefPubMed Rasouli MR, Restrepo C, Maltenfort MG, Purtill JJ, Parvizi J (2014) Risk factors for surgical site infection following total joint arthroplasty. J Bone Joint Surg Am 96(18):e158CrossRefPubMed
28.
go back to reference Reina N, Fennema P, Hourlier H (2017) The impact of mild peri-operative hypothermia on the effectiveness of tranexamic acid in total hip arthroplasty. Int Orthop 41(1):55–60CrossRefPubMed Reina N, Fennema P, Hourlier H (2017) The impact of mild peri-operative hypothermia on the effectiveness of tranexamic acid in total hip arthroplasty. Int Orthop 41(1):55–60CrossRefPubMed
29.
go back to reference Ren X, Ling L, Qi L et al (2021) Patients’ risk factors for periprosthetic joint infection in primary total hip arthroplasty: a meta-analysis of 40 studies. BMC Musculoskelet Disord 22(1):776CrossRefPubMedPubMedCentral Ren X, Ling L, Qi L et al (2021) Patients’ risk factors for periprosthetic joint infection in primary total hip arthroplasty: a meta-analysis of 40 studies. BMC Musculoskelet Disord 22(1):776CrossRefPubMedPubMedCentral
30.
go back to reference Sessler DI (2001) Complications and treatment of mild hypothermia. Anesthesiology 95(2):531–543CrossRef Sessler DI (2001) Complications and treatment of mild hypothermia. Anesthesiology 95(2):531–543CrossRef
31.
go back to reference Sessler DI, Olmsted RN, Kuelpmann R (2011) Forced-air warming does not worsen air quality in laminar flow operating rooms. Anesth Analg 113(6):1416–1421CrossRefPubMed Sessler DI, Olmsted RN, Kuelpmann R (2011) Forced-air warming does not worsen air quality in laminar flow operating rooms. Anesth Analg 113(6):1416–1421CrossRefPubMed
32.
go back to reference Shimokawa H (1999) Primary endothelial dysfunction: atherosclerosis. J Mol Cell Cardiol 31(1):23–37CrossRefPubMed Shimokawa H (1999) Primary endothelial dysfunction: atherosclerosis. J Mol Cell Cardiol 31(1):23–37CrossRefPubMed
33.
go back to reference Tjoakarfa C, David V, Ko A, Hau R (2017) Reflective blankets are as effective as forced air warmers in maintaining patient normothermia during hip and knee arthroplasty surgery. J Arthroplasty 32(2):624–627CrossRefPubMed Tjoakarfa C, David V, Ko A, Hau R (2017) Reflective blankets are as effective as forced air warmers in maintaining patient normothermia during hip and knee arthroplasty surgery. J Arthroplasty 32(2):624–627CrossRefPubMed
34.
go back to reference Verra WC, Beekhuizen SR, van Kampen PM, de Jager MC, Deijkers RLM, Tordoir RL (2018) Self-warming blanket versus forced-air warming in primary knee or hip replacement: a randomized controlled non-inferiority study. Asian J Anesthesiol 56(4):128–135 Verra WC, Beekhuizen SR, van Kampen PM, de Jager MC, Deijkers RLM, Tordoir RL (2018) Self-warming blanket versus forced-air warming in primary knee or hip replacement: a randomized controlled non-inferiority study. Asian J Anesthesiol 56(4):128–135
35.
go back to reference Wainwright TW, Gill M, McDonald DA et al (2020) Consensus statement for perioperative care in total hip replacement and total knee replacement surgery: Enhanced Recovery After Surgery (ERAS(®)) Society recommendations. Acta Orthop 91(1):3–19CrossRefPubMed Wainwright TW, Gill M, McDonald DA et al (2020) Consensus statement for perioperative care in total hip replacement and total knee replacement surgery: Enhanced Recovery After Surgery (ERAS(®)) Society recommendations. Acta Orthop 91(1):3–19CrossRefPubMed
36.
go back to reference Zmistowski B, Karam JA, Durinka JB, Casper DS, Parvizi J (2013) Periprosthetic joint infection increases the risk of one-year mortality. J Bone Joint Surg Am 95(24):2177–2184CrossRefPubMed Zmistowski B, Karam JA, Durinka JB, Casper DS, Parvizi J (2013) Periprosthetic joint infection increases the risk of one-year mortality. J Bone Joint Surg Am 95(24):2177–2184CrossRefPubMed
Metadata
Title
Analysis of the effects of intraoperative warming devices on surgical site infection in elective hip arthroplasty using a large nationwide database
Authors
Seung Hoon Kim
Suk-Yong Jang
Yonghan Cha
Bo-Yeon Kim
Hyo-Jung Lee
Gui-Ok Kim
Publication date
27-07-2023
Publisher
Springer Berlin Heidelberg
Published in
Archives of Orthopaedic and Trauma Surgery / Issue 12/2023
Print ISSN: 0936-8051
Electronic ISSN: 1434-3916
DOI
https://doi.org/10.1007/s00402-023-04917-8

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