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Published in: Archives of Orthopaedic and Trauma Surgery 6/2023

Open Access 05-07-2022 | Trauma Surgery

Should the early surgery threshold be moved to 72 h in over-85 patients with hip fracture? A single-center retrospective evaluation on 941 patients

Authors: Alessandro De Luca, Luigi Murena, Michela Zanetti, Paolo De Colle, Chiara Ratti, Gianluca Canton

Published in: Archives of Orthopaedic and Trauma Surgery | Issue 6/2023

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Abstract

Aim

Aim of the study was to assess whether early surgery and other clinical and orthogeriatric parameters could affect mortality rate in hip fracture patients aged > 85.

Materials and methods

Data regarding a 42-month period were retrospectively obtained from the institutional medical records and registry data. Gender, age, fracture pattern, surgical technique, type of anesthesia, timing of surgical intervention (within 24, 48 or 72 h from admission), days of hospitalization, mortality rate divided in intra-hospital, at 30 days and at 1 year were collected for the whole population. Some additional data were collected for an orthogeriatric subgroup.

Results

941 patients were considered, with a mean age of 89 years. Surgery was performed within 24, 48 and 72 h in 24.4%, 54.5% and 66.1% of cases, respectively. Intra-hospital mortality rate resulted to be 3.4%, while mortality at 30 days and 1 year resulted to be 4.5% and 31%, respectively. Early surgery within 48 and 72 h were significantly associated with a lower intra-hospital and 30-day mortality rate. In the orthogeriatric subgroup (394 patients), a significant association with a higher mortality rate was found for general anesthesia, number of comorbidities, ADL (Activities of Daily Living) < 3, transfer to other departments.

Conclusions

In over-85 hip fracture patients, the threshold for early surgery might be moved to 72 h to allow patients pre-operative stabilization and medical optimization as intra-hospital and 30-day mortality rates remain significantly lower. Advanced age, male sex, number of comorbidities, pre-operative dependency in ADL, general anesthesia, length of hospitalization and transfer to other departments were significantly related to mortality rate.
Literature
1.
go back to reference Dettoni F, Peveraro A, Dettoni A, Rossi R, Castoldi F, Zareh A et al (2012) Epidemiology of hip fractures in northwestern Italy: a multicentric regional study on incidence of hip fractures and their outcome at 3-year follow-up. Musculoskelet Surg 96(1):41–46PubMed Dettoni F, Peveraro A, Dettoni A, Rossi R, Castoldi F, Zareh A et al (2012) Epidemiology of hip fractures in northwestern Italy: a multicentric regional study on incidence of hip fractures and their outcome at 3-year follow-up. Musculoskelet Surg 96(1):41–46PubMed
2.
go back to reference Colais P, Di Martino M, Fusco D, Perucci CA, Davoli M (2015) The effect of early surgery after hip fracture on 1-year mortality. BMC Geriatr 15(1):141PubMedPubMedCentral Colais P, Di Martino M, Fusco D, Perucci CA, Davoli M (2015) The effect of early surgery after hip fracture on 1-year mortality. BMC Geriatr 15(1):141PubMedPubMedCentral
3.
go back to reference Piscitelli P, Feola M, Rao C, Celi M, Gasbarra E, Neglia C et al (2014) Ten years of hip fractures in Italy: for the first time a decreasing trend in elderly women. World J Orthop 5(3):386–391PubMedPubMedCentral Piscitelli P, Feola M, Rao C, Celi M, Gasbarra E, Neglia C et al (2014) Ten years of hip fractures in Italy: for the first time a decreasing trend in elderly women. World J Orthop 5(3):386–391PubMedPubMedCentral
4.
go back to reference Casaletto JA, Gatt R (2004) Post-operative mortality related to waiting time for hip fracture surgery. Injury 35(2):114–120PubMed Casaletto JA, Gatt R (2004) Post-operative mortality related to waiting time for hip fracture surgery. Injury 35(2):114–120PubMed
5.
go back to reference Cooper C (1997) The crippling consequences of fractures and their impact on quality of life. Am J Med 103(2A):12S–7S (discussion 17S–9S)PubMed Cooper C (1997) The crippling consequences of fractures and their impact on quality of life. Am J Med 103(2A):12S–7S (discussion 17S–9S)PubMed
6.
go back to reference Belmont PJ Jr, Garcia EJ, Romano D, Bader JO, Nelson KJ, Schoenfeld AJ (2014) Risk factors for complications and in-hospital mortality following hip fractures: a study using the National Trauma Data Bank. Arch Orthop Trauma Surg 134(5):597–604PubMed Belmont PJ Jr, Garcia EJ, Romano D, Bader JO, Nelson KJ, Schoenfeld AJ (2014) Risk factors for complications and in-hospital mortality following hip fractures: a study using the National Trauma Data Bank. Arch Orthop Trauma Surg 134(5):597–604PubMed
7.
go back to reference Forni S, Pieralli F, Sergi A, Lorini C, Bonaccorsi G, Vannucci A (2016) Mortality after hip fracture in the elderly: the role of a multidisciplinary approach and time to surgery in a retrospective observational study on 23,973 patients. Arch Gerontol Geriatr 66(124):13–17PubMed Forni S, Pieralli F, Sergi A, Lorini C, Bonaccorsi G, Vannucci A (2016) Mortality after hip fracture in the elderly: the role of a multidisciplinary approach and time to surgery in a retrospective observational study on 23,973 patients. Arch Gerontol Geriatr 66(124):13–17PubMed
8.
go back to reference Rosso F, Dettoni F, Bonasia DE, Olivero F, Mattei L, Bruzzone M et al (2016) Prognostic factors for mortality after hip fracture: operation within 48 hours is mandatory. Injury 47:S91–S97PubMed Rosso F, Dettoni F, Bonasia DE, Olivero F, Mattei L, Bruzzone M et al (2016) Prognostic factors for mortality after hip fracture: operation within 48 hours is mandatory. Injury 47:S91–S97PubMed
9.
go back to reference Clement ND, Aitken SA, Duckworth AD, McQueen MM, Court-Brown CM (2011) The outcome of fractures in very elderly patients. J Bone Joint Surg Br 93(6):806–810PubMed Clement ND, Aitken SA, Duckworth AD, McQueen MM, Court-Brown CM (2011) The outcome of fractures in very elderly patients. J Bone Joint Surg Br 93(6):806–810PubMed
10.
go back to reference Hu F, Jiang C, Shen J, Tang P, Wang Y (2012) Preoperative predictors for mortality following hip fracture surgery: a systematic review and meta-analysis. Injury 43(6):676–685PubMed Hu F, Jiang C, Shen J, Tang P, Wang Y (2012) Preoperative predictors for mortality following hip fracture surgery: a systematic review and meta-analysis. Injury 43(6):676–685PubMed
11.
go back to reference Lin C, Ou Y, Chen S, Liu Y, Lin J (2010) Comparison of artificial neural network and logistic regression models for predicting mortality in elderly patients with hip fracture. Injury 41(8):869–873PubMed Lin C, Ou Y, Chen S, Liu Y, Lin J (2010) Comparison of artificial neural network and logistic regression models for predicting mortality in elderly patients with hip fracture. Injury 41(8):869–873PubMed
12.
go back to reference Cenzer IS, Tang V, Boscardin WJ, Smith AK, Ritchie C, Wallhagen MI et al (2016) One-year mortality after hip fracture: development and validation of a prognostic index. J Am Geriatr Soc 64(9):1863–1868PubMedPubMedCentral Cenzer IS, Tang V, Boscardin WJ, Smith AK, Ritchie C, Wallhagen MI et al (2016) One-year mortality after hip fracture: development and validation of a prognostic index. J Am Geriatr Soc 64(9):1863–1868PubMedPubMedCentral
13.
go back to reference Haleem S, Lutchman L, Mayahi R, Grice JE, Parker MJ (2008) Mortality following hip fracture: trends and geographical variations over the last 40 years. Injury 39(10):1157–1163PubMed Haleem S, Lutchman L, Mayahi R, Grice JE, Parker MJ (2008) Mortality following hip fracture: trends and geographical variations over the last 40 years. Injury 39(10):1157–1163PubMed
14.
go back to reference Haentjens P, Magaziner J, Colón-Emeric CS, Vanderschueren D, Milisen K, Velkeniers B et al (2010) Meta-analysis: excess mortality after hip fracture among older women and men. Ann Intern Med 152(6):380PubMedPubMedCentral Haentjens P, Magaziner J, Colón-Emeric CS, Vanderschueren D, Milisen K, Velkeniers B et al (2010) Meta-analysis: excess mortality after hip fracture among older women and men. Ann Intern Med 152(6):380PubMedPubMedCentral
15.
go back to reference Moran CG, Wenn RT, Sikand M, Taylor AM (2005) Early mortality after hip fracture: is delay before surgery important? J Bone Joint Surg Am 87(3):483–489PubMed Moran CG, Wenn RT, Sikand M, Taylor AM (2005) Early mortality after hip fracture: is delay before surgery important? J Bone Joint Surg Am 87(3):483–489PubMed
16.
go back to reference Richmond J, Aharonoff GB, Zuckerman JD, Koval KJ (2003) Mortality risk after hip fracture. J Orthop Trauma 17(8 Suppl):S2–S5PubMed Richmond J, Aharonoff GB, Zuckerman JD, Koval KJ (2003) Mortality risk after hip fracture. J Orthop Trauma 17(8 Suppl):S2–S5PubMed
17.
go back to reference Roche JJW, Wenn RT, Sahota O, Moran CG (2005) Effect of comorbidities and postoperative complications on mortality after hip fracture in elderly people: prospective observational cohort study. BMJ 331(7529):1374PubMedPubMedCentral Roche JJW, Wenn RT, Sahota O, Moran CG (2005) Effect of comorbidities and postoperative complications on mortality after hip fracture in elderly people: prospective observational cohort study. BMJ 331(7529):1374PubMedPubMedCentral
18.
go back to reference Rosell PAE, Parker MJ (2003) Functional outcome after hip fracture. A 1-year prospective outcome study of 275 patients. Injury 34(7):529–532PubMed Rosell PAE, Parker MJ (2003) Functional outcome after hip fracture. A 1-year prospective outcome study of 275 patients. Injury 34(7):529–532PubMed
19.
go back to reference Meessen JMTA, Pisani S, Gambino ML, Bonarrigo D, van Schoor NM, Fozzato S et al (2014) Assessment of mortality risk in elderly patients after proximal femoral fracture. Orthopedics 37(2):e194–e200PubMed Meessen JMTA, Pisani S, Gambino ML, Bonarrigo D, van Schoor NM, Fozzato S et al (2014) Assessment of mortality risk in elderly patients after proximal femoral fracture. Orthopedics 37(2):e194–e200PubMed
20.
go back to reference Ribeiro TA, Premaor MO, Larangeira JA, Brito LG, Luft M, Guterres LW et al (2014) Predictors of hip fracture mortality at a general hospital in South Brazil: an unacceptable surgical delay. Clinics (Sao Paulo) 69(4):253–258PubMedPubMedCentral Ribeiro TA, Premaor MO, Larangeira JA, Brito LG, Luft M, Guterres LW et al (2014) Predictors of hip fracture mortality at a general hospital in South Brazil: an unacceptable surgical delay. Clinics (Sao Paulo) 69(4):253–258PubMedPubMedCentral
21.
go back to reference Shiga T, Wajima Z, Ohe Y (2008) Is operative delay associated with increased mortality of hip fracture patients? Systematic review, meta-analysis, and meta-regression. Can J Anaesth 55(3):146–154PubMed Shiga T, Wajima Z, Ohe Y (2008) Is operative delay associated with increased mortality of hip fracture patients? Systematic review, meta-analysis, and meta-regression. Can J Anaesth 55(3):146–154PubMed
22.
go back to reference Villar RN, Allen SM, Barnes SJ (1986) Hip fractures in healthy patients: operative delay versus prognosis. Br Med J (Clin Res Ed) 293(6556):1203–1204PubMed Villar RN, Allen SM, Barnes SJ (1986) Hip fractures in healthy patients: operative delay versus prognosis. Br Med J (Clin Res Ed) 293(6556):1203–1204PubMed
23.
go back to reference Yonezawa T, Yamazaki K, Atsumi T, Obara S (2009) Influence of the timing of surgery on mortality and activity of hip fracture in elderly patients. J Orthop Sci 14(5):566–573PubMed Yonezawa T, Yamazaki K, Atsumi T, Obara S (2009) Influence of the timing of surgery on mortality and activity of hip fracture in elderly patients. J Orthop Sci 14(5):566–573PubMed
24.
go back to reference Simunovic N, Devereaux PJ, Sprague S, Guyatt GH, Schemitsch E, Debeer J et al (2010) Effect of early surgery after hip fracture on mortality and complications: systematic review and meta-analysis. CMAJ 182(15):1609–1616PubMedPubMedCentral Simunovic N, Devereaux PJ, Sprague S, Guyatt GH, Schemitsch E, Debeer J et al (2010) Effect of early surgery after hip fracture on mortality and complications: systematic review and meta-analysis. CMAJ 182(15):1609–1616PubMedPubMedCentral
25.
go back to reference Bottle A, Aylin P (2006) Mortality associated with delay in operation after hip fracture: observational study. BMJ 332(7547):947–951PubMedPubMedCentral Bottle A, Aylin P (2006) Mortality associated with delay in operation after hip fracture: observational study. BMJ 332(7547):947–951PubMedPubMedCentral
26.
go back to reference Grimes JP, Gregory PM, Noveck H, Butler MS, Carson JL (2002) The effects of time-to-surgery on mortality and morbidity in patients following hip fracture. Am J Med 112(9):702–709PubMed Grimes JP, Gregory PM, Noveck H, Butler MS, Carson JL (2002) The effects of time-to-surgery on mortality and morbidity in patients following hip fracture. Am J Med 112(9):702–709PubMed
27.
go back to reference Manninger J, Kazar G, Fekete G, Fekete K, Frenyo S, Gyarfas F et al (1989) Significance of urgent (within 6h) internal fixation in the management of fractures of the neck of the femur. Injury 20(2):101–105PubMed Manninger J, Kazar G, Fekete G, Fekete K, Frenyo S, Gyarfas F et al (1989) Significance of urgent (within 6h) internal fixation in the management of fractures of the neck of the femur. Injury 20(2):101–105PubMed
28.
go back to reference Orosz GM, Magaziner J, Hannan EL, Morrison RS, Koval K, Gilbert M et al (2004) Association of timing of surgery for hip fracture and patient outcomes. JAMA 291(14):1738–1743PubMedPubMedCentral Orosz GM, Magaziner J, Hannan EL, Morrison RS, Koval K, Gilbert M et al (2004) Association of timing of surgery for hip fracture and patient outcomes. JAMA 291(14):1738–1743PubMedPubMedCentral
29.
go back to reference Perez JV, Warwick DJ, Case CP, Bannister GC (1995) Death after proximal femoral fracture—an autopsy study. Injury 26(4):237–240PubMed Perez JV, Warwick DJ, Case CP, Bannister GC (1995) Death after proximal femoral fracture—an autopsy study. Injury 26(4):237–240PubMed
30.
go back to reference Rogers FB, Shackford SR, Keller MS (1995) Early fixation reduces morbidity and mortality in elderly patients with hip fractures from low-impact falls. J Trauma 39(2):261–265PubMed Rogers FB, Shackford SR, Keller MS (1995) Early fixation reduces morbidity and mortality in elderly patients with hip fractures from low-impact falls. J Trauma 39(2):261–265PubMed
31.
go back to reference Carretta E, Bochicchio V, Rucci P, Fabbri G, Laus M, Fantini MP (2011) Hip fracture: effectiveness of early surgery to prevent 30-day mortality. Int Orthop 35(3):419–424PubMed Carretta E, Bochicchio V, Rucci P, Fabbri G, Laus M, Fantini MP (2011) Hip fracture: effectiveness of early surgery to prevent 30-day mortality. Int Orthop 35(3):419–424PubMed
32.
go back to reference McGuire KJ, Bernstein J, Polsky D, Silber JH (2004) The 2004 Marshall Urist award: delays until surgery after hip fracture increases mortality. Clin Orthop Relat Res 428:294–301 McGuire KJ, Bernstein J, Polsky D, Silber JH (2004) The 2004 Marshall Urist award: delays until surgery after hip fracture increases mortality. Clin Orthop Relat Res 428:294–301
33.
go back to reference Zuckerman JD, Skovron ML, Koval KJ, Aharonoff G, Frankel VH (1995) Postoperative complications and mortality associated with operative delay in older patients who have a fracture of the hip. J Bone Joint Surg Am 77(10):1551–1556PubMed Zuckerman JD, Skovron ML, Koval KJ, Aharonoff G, Frankel VH (1995) Postoperative complications and mortality associated with operative delay in older patients who have a fracture of the hip. J Bone Joint Surg Am 77(10):1551–1556PubMed
34.
go back to reference Holt G, Smith R, Duncan K, Finlayson DF, Gregori A (2008) Early mortality after surgical fixation of hip fractures in the elderly: an analysis of data from the Scottish hip fracture audit. J Bone Joint Surg Br 90(10):1357–1363PubMed Holt G, Smith R, Duncan K, Finlayson DF, Gregori A (2008) Early mortality after surgical fixation of hip fractures in the elderly: an analysis of data from the Scottish hip fracture audit. J Bone Joint Surg Br 90(10):1357–1363PubMed
35.
go back to reference Sund R, Liski A (2005) Quality effects of operative delay on mortality in hip fracture treatment. Qual Saf Health Care 14(5):371–377PubMedPubMedCentral Sund R, Liski A (2005) Quality effects of operative delay on mortality in hip fracture treatment. Qual Saf Health Care 14(5):371–377PubMedPubMedCentral
36.
go back to reference Rodriguez-Fernandez P, Adarraga-Cansino D, Carpintero P (2011) Effects of delayed hip fracture surgery on mortality and morbidity in elderly patients. Clin Orthop Relat Res 469(11):3218–3221PubMedPubMedCentral Rodriguez-Fernandez P, Adarraga-Cansino D, Carpintero P (2011) Effects of delayed hip fracture surgery on mortality and morbidity in elderly patients. Clin Orthop Relat Res 469(11):3218–3221PubMedPubMedCentral
37.
go back to reference Khan SK, Kalra S, Khanna A, Thiruvengada MM, Parker MJ (2009) Timing of surgery for hip fractures: a systematic review of 52 published studies involving 291,413 patients. Injury 40(7):692–697PubMed Khan SK, Kalra S, Khanna A, Thiruvengada MM, Parker MJ (2009) Timing of surgery for hip fractures: a systematic review of 52 published studies involving 291,413 patients. Injury 40(7):692–697PubMed
38.
go back to reference Ram GG, Govardhan P (2019) In-hospital mortality following proximal femur fractures in elderly population. Surg J (N Y) 5(2):e53–e56PubMed Ram GG, Govardhan P (2019) In-hospital mortality following proximal femur fractures in elderly population. Surg J (N Y) 5(2):e53–e56PubMed
39.
go back to reference Broos PL, Van Haaften KI, Stappaerts KH, Gruwez JA (1989) Hip fractures in the elderly. Mortality, functional results and social readaptation. Int Surg 74(3):191–194PubMed Broos PL, Van Haaften KI, Stappaerts KH, Gruwez JA (1989) Hip fractures in the elderly. Mortality, functional results and social readaptation. Int Surg 74(3):191–194PubMed
40.
go back to reference Welford P, Jones CS, Davies G, Kunutsor SK, Costa ML, Sayers A, Whitehouse MR (2021) The association between surgical fixation of hip fractures within 24 hours and mortality: a systematic review and meta-analysis. Bone Joint J 103B(7):1176–1186 Welford P, Jones CS, Davies G, Kunutsor SK, Costa ML, Sayers A, Whitehouse MR (2021) The association between surgical fixation of hip fractures within 24 hours and mortality: a systematic review and meta-analysis. Bone Joint J 103B(7):1176–1186
41.
go back to reference Lizaur-Utrilla A, Gonzalez-Navarro B, Vizcaya-Moreno MF, Miralles Muñoz FA, Gonzalez-Parreño S, Lopez-Prats FA (2019) Reasons for delaying surgery following hip fractures and its impact on one year mortality. Int Orthop 43(2):441–448PubMed Lizaur-Utrilla A, Gonzalez-Navarro B, Vizcaya-Moreno MF, Miralles Muñoz FA, Gonzalez-Parreño S, Lopez-Prats FA (2019) Reasons for delaying surgery following hip fractures and its impact on one year mortality. Int Orthop 43(2):441–448PubMed
42.
go back to reference Folbert EC, Hegeman JH, Vermeer M, Regtuijt EM, van der Velde D, Ten Duis HJ et al (2017) Improved 1-year mortality in elderly patients with a hip fracture following integrated orthogeriatric treatment. Osteoporos Int 28(1):269–277PubMed Folbert EC, Hegeman JH, Vermeer M, Regtuijt EM, van der Velde D, Ten Duis HJ et al (2017) Improved 1-year mortality in elderly patients with a hip fracture following integrated orthogeriatric treatment. Osteoporos Int 28(1):269–277PubMed
43.
go back to reference Keppler AM, Holzschuh J, Pfeufer D, Neuerburg C, Kammerlander C, Böcker W et al (2020) Postoperative physical activity in orthogeriatric patients—new insights with continuous monitoring. Injury 51(3):628–632PubMed Keppler AM, Holzschuh J, Pfeufer D, Neuerburg C, Kammerlander C, Böcker W et al (2020) Postoperative physical activity in orthogeriatric patients—new insights with continuous monitoring. Injury 51(3):628–632PubMed
44.
go back to reference Gosch M, Hoffmann-Weltin Y, Roth T, Blauth M, Nicholas JA, Kammerlander C (2016) Orthogeriatric co-management improves the outcome of long-term care residents with fragility fractures. Arch Orthop Trauma Surg 136(10):1403–1409PubMedPubMedCentral Gosch M, Hoffmann-Weltin Y, Roth T, Blauth M, Nicholas JA, Kammerlander C (2016) Orthogeriatric co-management improves the outcome of long-term care residents with fragility fractures. Arch Orthop Trauma Surg 136(10):1403–1409PubMedPubMedCentral
45.
go back to reference Sabharwal S, Wilson H (2015) Orthogeriatrics in the management of frail older patients with a fragility fracture. Osteoporos Int 26(10):2387–2399PubMed Sabharwal S, Wilson H (2015) Orthogeriatrics in the management of frail older patients with a fragility fracture. Osteoporos Int 26(10):2387–2399PubMed
46.
go back to reference Abrahamsen C, Nørgaard B, Draborg E, Nielsen MF (2019) The impact of an orthogeriatric intervention in patients with fragility fractures: a cohort study. BMC Geriatr 19(1):268PubMedPubMedCentral Abrahamsen C, Nørgaard B, Draborg E, Nielsen MF (2019) The impact of an orthogeriatric intervention in patients with fragility fractures: a cohort study. BMC Geriatr 19(1):268PubMedPubMedCentral
47.
go back to reference Frost SA, Nguyen ND, Black DA, Eisman JA, Nguyen TV (2011) Risk factors for in-hospital post-hip fracture mortality. Bone 49(3):553–558PubMed Frost SA, Nguyen ND, Black DA, Eisman JA, Nguyen TV (2011) Risk factors for in-hospital post-hip fracture mortality. Bone 49(3):553–558PubMed
48.
go back to reference Henderson CY, Ryan JP (2015) Predicting mortality following hip fracture: an analysis of comorbidities and complications. Ir J Med Sci 184(3):667–671PubMed Henderson CY, Ryan JP (2015) Predicting mortality following hip fracture: an analysis of comorbidities and complications. Ir J Med Sci 184(3):667–671PubMed
49.
go back to reference Guzon-Illescas O, Perez Fernandez E, Crespí Villarias N, Quirós Donate FJ, Peña M, Alonso-Blas C et al (2019) Mortality after osteoporotic hip fracture: incidence, trends, and associated factors. J Orthop Surg Res 14(1):203PubMedPubMedCentral Guzon-Illescas O, Perez Fernandez E, Crespí Villarias N, Quirós Donate FJ, Peña M, Alonso-Blas C et al (2019) Mortality after osteoporotic hip fracture: incidence, trends, and associated factors. J Orthop Surg Res 14(1):203PubMedPubMedCentral
50.
go back to reference Moja L, Piatti A, Pecoraro V, Ricci C, Virgili G, Salanti G et al (2012) Timing matters in hip fracture surgery: patients operated within 48 hours have better outcomes. A meta-analysis and meta-regression of over 190,000 patients. PLoS One 7(10):e46175PubMedPubMedCentral Moja L, Piatti A, Pecoraro V, Ricci C, Virgili G, Salanti G et al (2012) Timing matters in hip fracture surgery: patients operated within 48 hours have better outcomes. A meta-analysis and meta-regression of over 190,000 patients. PLoS One 7(10):e46175PubMedPubMedCentral
51.
go back to reference Menzies IB, Mendelson DA, Kates SL, Friedman SM (2012) The impact of comorbidity on perioperative outcomes of hip fractures in a geriatric fracture model. Geriatr Orthop Surg Rehabil 3(3):129–134PubMedPubMedCentral Menzies IB, Mendelson DA, Kates SL, Friedman SM (2012) The impact of comorbidity on perioperative outcomes of hip fractures in a geriatric fracture model. Geriatr Orthop Surg Rehabil 3(3):129–134PubMedPubMedCentral
52.
go back to reference Holt G, Smith R, Duncan K, McKeown DW (2010) Does delay to theatre for medical reasons affect the peri-operative mortality in patients with a fracture of the hip? J Bone Joint Surg Br 92(6):835–841PubMed Holt G, Smith R, Duncan K, McKeown DW (2010) Does delay to theatre for medical reasons affect the peri-operative mortality in patients with a fracture of the hip? J Bone Joint Surg Br 92(6):835–841PubMed
53.
go back to reference Cha YH, Ha YC, Yoo JI, Min YS, Lee YK, Koo KH (2017) Effect of causes of surgical delay on early and late mortality in patients with proximal hip fracture. Arch Orthop Trauma Surg 137(5):625–630PubMed Cha YH, Ha YC, Yoo JI, Min YS, Lee YK, Koo KH (2017) Effect of causes of surgical delay on early and late mortality in patients with proximal hip fracture. Arch Orthop Trauma Surg 137(5):625–630PubMed
54.
go back to reference Morri M, Ambrosi E, Chiari P, Orlandi Magli A, Gazineo D, D’Alessandro F, Forni C (2019) One-year mortality after hip fracture surgery and prognostic factors: a prospective cohort study. Sci Rep. 9(1):18718PubMedPubMedCentral Morri M, Ambrosi E, Chiari P, Orlandi Magli A, Gazineo D, D’Alessandro F, Forni C (2019) One-year mortality after hip fracture surgery and prognostic factors: a prospective cohort study. Sci Rep. 9(1):18718PubMedPubMedCentral
55.
go back to reference Klestil T, Röder C, Stotter C, Winkler B, Nehrer S, Lutz M, Klerings I, Wagner G, Gartlehner G, Nussbaumer-Streit B (2018) Impact of timing of surgery in elderly hip fracture patients: a systematic review and meta-analysis. Sci Rep 8(1):13933PubMedPubMedCentral Klestil T, Röder C, Stotter C, Winkler B, Nehrer S, Lutz M, Klerings I, Wagner G, Gartlehner G, Nussbaumer-Streit B (2018) Impact of timing of surgery in elderly hip fracture patients: a systematic review and meta-analysis. Sci Rep 8(1):13933PubMedPubMedCentral
56.
go back to reference Kristiansson J, Hagberg E, Nellgård B (2020) The influence of time-to-surgery on mortality after a hip fracture. Acta Anaesthesiol Scand 64(3):347–353PubMed Kristiansson J, Hagberg E, Nellgård B (2020) The influence of time-to-surgery on mortality after a hip fracture. Acta Anaesthesiol Scand 64(3):347–353PubMed
57.
go back to reference Schoeneberg C, Aigner R, Pass B, Volland R, Eschbach D, Peiris SE, Ruchholtz S, Lendemans S, Alters Trauma Register DGU (2021) Effect of time-to-surgery on in-house mortality during orthogeriatric treatment following hip fracture: a retrospective analysis of prospectively collected data from 16,236 patients of the Alters Trauma Register DGU®. Injury 52(3):554–561PubMed Schoeneberg C, Aigner R, Pass B, Volland R, Eschbach D, Peiris SE, Ruchholtz S, Lendemans S, Alters Trauma Register DGU (2021) Effect of time-to-surgery on in-house mortality during orthogeriatric treatment following hip fracture: a retrospective analysis of prospectively collected data from 16,236 patients of the Alters Trauma Register DGU®. Injury 52(3):554–561PubMed
58.
go back to reference Kannegaard PN, van der Mark S, Eiken P, Abrahamsen B (2010) Excess mortality in men compared with women following a hip fracture. National analysis of comedications, comorbidity and survival. Age Ageing 39(2):203–209PubMed Kannegaard PN, van der Mark S, Eiken P, Abrahamsen B (2010) Excess mortality in men compared with women following a hip fracture. National analysis of comedications, comorbidity and survival. Age Ageing 39(2):203–209PubMed
59.
go back to reference Nordström P, Gustafson Y, Michaëlsson K, Nordström A (2015) Length of hospital stay after hip fracture and short term risk of death after discharge: a total cohort study in Sweden. BMJ 350:h696PubMedPubMedCentral Nordström P, Gustafson Y, Michaëlsson K, Nordström A (2015) Length of hospital stay after hip fracture and short term risk of death after discharge: a total cohort study in Sweden. BMJ 350:h696PubMedPubMedCentral
60.
go back to reference Cree AK, Nade S (1999) How to predict return to the community after fractured proximal femur in the elderly. Aust N Z J Surg 69(10):723–725PubMed Cree AK, Nade S (1999) How to predict return to the community after fractured proximal femur in the elderly. Aust N Z J Surg 69(10):723–725PubMed
61.
go back to reference González-Zabaleta J, Pita-Fernandez S, Seoane-Pillado T, López-Calviño B, Gonzalez-Zabaleta JL (2015) Dependence for basic and instrumental activities of daily living after hip fractures. Arch Gerontol Geriatr 60(1):66–70PubMed González-Zabaleta J, Pita-Fernandez S, Seoane-Pillado T, López-Calviño B, Gonzalez-Zabaleta JL (2015) Dependence for basic and instrumental activities of daily living after hip fractures. Arch Gerontol Geriatr 60(1):66–70PubMed
62.
go back to reference Cummings SR, Kelsey JL, Nevitt MC, O’Dowd KJ (1985) Epidemiology of osteoporosis and osteoporotic fractures. Epidemiol Rev 7:178–208PubMed Cummings SR, Kelsey JL, Nevitt MC, O’Dowd KJ (1985) Epidemiology of osteoporosis and osteoporotic fractures. Epidemiol Rev 7:178–208PubMed
63.
go back to reference Elmerson S, Zetterberg C, Andersson GB (1988) Ten-year survival after fractures of the proximal end of the femur. Gerontology 34(4):186–191PubMed Elmerson S, Zetterberg C, Andersson GB (1988) Ten-year survival after fractures of the proximal end of the femur. Gerontology 34(4):186–191PubMed
64.
go back to reference Holmberg S, Thorngren KG (1987) Statistical analysis of femoral neck fractures based on 3053 cases. Clin Orthop Relat Res 218:32–41 Holmberg S, Thorngren KG (1987) Statistical analysis of femoral neck fractures based on 3053 cases. Clin Orthop Relat Res 218:32–41
65.
go back to reference Gauthier JL, Hamelberg W (1963) Hip fractures. Influence of anesthesia on the patient’s hospital course. Anesth Analg 42:609–615PubMed Gauthier JL, Hamelberg W (1963) Hip fractures. Influence of anesthesia on the patient’s hospital course. Anesth Analg 42:609–615PubMed
66.
go back to reference Sutcliffe AJ, Parker M (1994) Mortality after spinal and general anaesthesia for surgical fixation of hip fractures. Anaesthesia 49(3):237–240PubMed Sutcliffe AJ, Parker M (1994) Mortality after spinal and general anaesthesia for surgical fixation of hip fractures. Anaesthesia 49(3):237–240PubMed
67.
go back to reference Roberts KC, Brox WT, Jevsevar DS, Sevarino K (2015) Management of hip fractures in the elderly. J Am Acad Orthop Surg 23(2):131–137PubMed Roberts KC, Brox WT, Jevsevar DS, Sevarino K (2015) Management of hip fractures in the elderly. J Am Acad Orthop Surg 23(2):131–137PubMed
68.
go back to reference Guay J, Parker MJ, Gajendragadkar PR, Kopp S (2016) Anaesthesia for hip fracture surgery in adults. Cochrane Database Syst Rev 2(2):CD000521PubMed Guay J, Parker MJ, Gajendragadkar PR, Kopp S (2016) Anaesthesia for hip fracture surgery in adults. Cochrane Database Syst Rev 2(2):CD000521PubMed
69.
go back to reference Van Waesberghe J, Stevanovic A, Rossaint R, Coburn M (2017) General vs. neuraxial anaesthesia in hip fracture patients: a systematic review and meta-analysis. BMC Anesthesiol 17(1):87PubMedPubMedCentral Van Waesberghe J, Stevanovic A, Rossaint R, Coburn M (2017) General vs. neuraxial anaesthesia in hip fracture patients: a systematic review and meta-analysis. BMC Anesthesiol 17(1):87PubMedPubMedCentral
70.
go back to reference Gundel O, Thygesen LC, Gögenur I, Ekeloef S (2020) Postoperative mortality after a hip fracture over a 15-year period in Denmark: a national register study. Acta Orthop 91(1):58–62PubMed Gundel O, Thygesen LC, Gögenur I, Ekeloef S (2020) Postoperative mortality after a hip fracture over a 15-year period in Denmark: a national register study. Acta Orthop 91(1):58–62PubMed
71.
go back to reference Cornwall R, Gilbert MS, Koval KJ, Strauss E, Siu AL (2004) Functional outcomes and mortality vary among different types of hip fractures: a function of patient characteristics. Clin Orthop Relat Res 425:64–71 Cornwall R, Gilbert MS, Koval KJ, Strauss E, Siu AL (2004) Functional outcomes and mortality vary among different types of hip fractures: a function of patient characteristics. Clin Orthop Relat Res 425:64–71
72.
go back to reference Kang H-Y, Yang K, Kim YN, Moon S, Choi W, Kang DR et al (2010) Incidence and mortality of hip fracture among the elderly population in South Korea: a population-based study using the national health insurance claims data. BMC Public Health 10(1):230PubMedPubMedCentral Kang H-Y, Yang K, Kim YN, Moon S, Choi W, Kang DR et al (2010) Incidence and mortality of hip fracture among the elderly population in South Korea: a population-based study using the national health insurance claims data. BMC Public Health 10(1):230PubMedPubMedCentral
73.
go back to reference Lyles KW, Colón-Emeric CS, Magaziner JS, Adachi JD, Pieper CF, Mautalen C et al (2007) Zoledronic acid and clinical fractures and mortality after hip fracture. N Engl J Med 357(18):1799–1809PubMed Lyles KW, Colón-Emeric CS, Magaziner JS, Adachi JD, Pieper CF, Mautalen C et al (2007) Zoledronic acid and clinical fractures and mortality after hip fracture. N Engl J Med 357(18):1799–1809PubMed
Metadata
Title
Should the early surgery threshold be moved to 72 h in over-85 patients with hip fracture? A single-center retrospective evaluation on 941 patients
Authors
Alessandro De Luca
Luigi Murena
Michela Zanetti
Paolo De Colle
Chiara Ratti
Gianluca Canton
Publication date
05-07-2022
Publisher
Springer Berlin Heidelberg
Published in
Archives of Orthopaedic and Trauma Surgery / Issue 6/2023
Print ISSN: 0936-8051
Electronic ISSN: 1434-3916
DOI
https://doi.org/10.1007/s00402-022-04509-y

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