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17-08-2023 | Malaria | Original Contribution

Dietary intake of preformed vitamin A and provitamin A carotenoids are not associated with serum retinol and carotenoid concentrations among children 36–59 months of age in rural Burkina Faso: a cross-sectional study

Authors: Olivier O. Sombié, Augustin N. Zeba, Jérome W. Somé, Adama Kazienga, Jeoffray Diendere, Jean F. Bationo, Christopher Davis, Michael Grahn, Sherry Tanumihardjo, Stefaan De Henauw, Souheila Abbeddou

Published in: European Journal of Nutrition | Issue 8/2023

Abstract

Purpose

This study aimed to assess the association between dietary intake of preformed vitamin A (VA) and pro-VA carotenoids and serum retinol and carotenoid concentrations among 36–59-month-old children in a rural area in Burkina Faso.

Methods

Two community-based cross-sectional studies were conducted in a rural area of Burkina Faso and included 115 children aged 36–59 months. Dietary intake of preformed VA and pro-VA was assessed directly by 24-h dietary recall. Serum retinol and carotenoid (α- and β-carotene, and β-cryptoxanthin) concentrations were measured. The associations between serum retinol and carotenoid concentrations and their respective dietary intake were assessed by multiple linear regression.

Results

Geometric mean [95% CI] adjusted serum retinol concentration in children was 0.86 [0.81; 0.92] µmol/L. The prevalence of low adjusted serum retinol concentration (< 0.7 µmol/L) was 26.8%. Geometric mean [95% CI] serum carotenoid concentrations were: α-carotene (0.03 [0.02; 0.03] µmol/L), β-carotene (0.14 [0.12; 0.16] µmol/L), and β-cryptoxanthin (0.17 [0.15; 0.21] µmol/L). Dietary intakes of α- and β-carotene and adjusted serum retinol and α-carotene concentrations were significantly higher during the rainy season. In multiple linear regressions, no associations were found between dietary intakes of preformed VA and pro-VA carotenoids and serum retinol and carotenoid concentrations in children aged 36–59 months in Burkina Faso. There was no effect of season on the associations between preformed VA and pro-VA carotenoids intake and serum retinol and carotenoid concentrations.

Conclusions

This study shows that dietary intakes of preformed VA and pro-VA carotenoids based on 24-h dietary recall method cannot be used as proxy of serum retinol and carotenoid concentrations in this population.

Trial registration

The study was registered retrospectively (22 March 2018) as a clinical trial with the Pan African Clinical Trials Registry (Cochrane South Africa; PACTR201803002999356).

WHO (2004) Vitamin and mineral requirements in human nutrition. WHO, Geneva
Stevens GA, Bennett JE, Hennocq Q, Lu Y, De-Regil LM, Rogers L, Danaei G, Li G, White RA, Flaxman SR (2015) Trends and mortality effects of vitamin A deficiency in children in 138 low-income and middle-income countries between 1991 and 2013: a pooled analysis of population-based surveys. Lancet Glob Health 3(9):e528–e536. https://doi.org/10.1016/S2214-109X(15)00039-XView ArticlePubMed
WHO (2009) Global prevalence of vitamin A deficiency in populations at risk 1995–2005: WHO global database on vitamin A deficiency
Qi Y, Niu Q, Zhu X, Zhao X, Yang W, Wang X (2016) Relationship between deficiencies in vitamin A and E and occurrence of infectious diseases among children. Eur Rev Med Pharmacol Sci 20(23):5009–5012PubMed
Tanumihardjo SA (2011) Vitamin A: biomarkers of nutrition for development. Am J Clin Nutr 94(2):658S-665S. https://doi.org/10.3945/ajcn.110.005777View ArticlePubMedPubMed Central
Prasad M, Takkinen HM, Uusitalo L, Tapanainen H, Ovaskainen ML, Alfthan G, Erlund I, Ahonen S, Åkerlund M, Toppari J et al (2018) Carotenoid intake and serum concentration in young Finnish children and their relation with fruit and vegetable consumption. Nutrients. https://doi.org/10.3390/nu10101533View ArticlePubMedPubMed Central
Daun H (1988) The chemistry of carotenoids and their importance in food. Clin Nutr 7(3):97–100
Erdman J (1988) The physiologic chemistry of carotenes in man. Clin Nutr 7(3):101–105
Haskell MJ, Pandey P, Graham JM, Peerson JM, Shrestha RK, Brown KH (2005) Recovery from impaired dark adaptation in nightblind pregnant Nepali women who receive small daily doses of vitamin A as amaranth leaves, carrots, goat liver, vitamin A-fortified rice, or retinyl palmitate. Am J Clin Nutr 81(2):461–471. https://doi.org/10.1093/ajcn.81.2.461View ArticlePubMed
Parker RS (1996) Absorption, metabolism, and transport of carotenoids. FASEB J 10(5):542–551View ArticlePubMed
Bationo JF, Zeba AN, Abbeddou S, Coulibaly ND, Sombier OO, Sheftel J, Bassole IHN, Barro N, Ouedraogo JB, Tanumihardjo SA (2018) Serum carotenoids reveal poor fruit and vegetable intake among school children in Burkina Faso. Nutrients. https://doi.org/10.3390/nu10101422View ArticlePubMedPubMed Central
Ramakrishnan U, Martorell R, Latham MC, Abel R (1999) Dietary vitamin A intakes of preschool-age children in South India. J Nutr 129(11):2021–2027. https://doi.org/10.1093/jn/129.11.2021View ArticlePubMed
Zeitlin MF, Megawangi R, Kramer EM, Armstrong HC (1992) Mothers’ and children’s intakes of vitamin A in rural Bangladesh. Am J Clin Nutr 56(1):136–147. https://doi.org/10.1093/ajcn/56.1.136View ArticlePubMed
Tanumihardjo SA, Palacios N, Pixley KV (2010) Provitamin a carotenoid bioavailability: what really matters? Int J Vitam Nutr Res 80(4–5):336–350. https://doi.org/10.1024/0300-9831/a000042View ArticlePubMed
West KP Jr, Mehra S (2010) Vitamin A intake and status in populations facing economic stress. J Nutr 140(1):201s–207s. https://doi.org/10.3945/jn.109.112730View ArticlePubMed
Tanumihardjo SA, Howe JA (2005) Twice the amount of alpha-carotene isolated from carrots is as effective as beta-carotene in maintaining the vitamin A status of Mongolian gerbils. J Nutr 135(11):2622–2626. https://doi.org/10.1093/jn/135.11.2622View ArticlePubMed
De Pee S, West CE, Muhilal KD, Hautvast JG (1995) Lack of improvement in vitamin A status with increased consumption of dark-green leafy vegetables. Lancet (London, England) 346(8967):75–81. https://doi.org/10.1016/s0140-6736(95)92111-7View ArticlePubMed
District sanitaire de Dandé (2016) Plan d'action 2016 du district sanitaire de Dandé, Regions des Hauts Bassins, Burkina Faso
Ministère de la Santé (2012) Enquête Démographique et de Santé et à Indicateurs Multiples du Burkina Faso
WHO (2006) Multicentre Growth Reference Study Group 2006. WHO child growth standards: length/height-for age, weight-for-age, weight for length, weight for height: methods and development. World Health Organization, Geneva, p 312
Gibson RS (2005) Principles of nutritional assessment. Oxford University Press, Oxford
Vásquez-Caicedo A, Bell S, Hartmann B (2008) Report on collection of rules on use of recipe calculation procedures including the use of yield and retention factors for imputing nutrient values for composite foods. European Food Information Resource Network, Brussels
Bognár A (2002) Tables on weight yield of food and retention factors of food constituents for the calculation of nutrient composition of cooked foods (dishes). BFE Karlsruhe, Germany
Vincent A, Grande F, Compaoré E, Amponsah Annor G, Addy P, Aburime L, Ahmed D, Bih Loh A, Dahdouh Cabia S, Deflache N (2019) FAO/INFOODS Food Composition Table for Western Africa (2019) User Guide & condensed food composition table. Table de Composition des Aliments FAO/INFOODS Pour L’afrique de L’ouest
Gannon BM, Valentine AR, Davis CR, Howe JA, Tanumihardjo SA (2018) Duration of Retinol Isotope Dilution Studies with Compartmental Modeling Affects Model Complexity, Kinetic Parameters, and Calculated Vitamin A Stores in US Women. J Nutr 148(8):1387–1396. https://doi.org/10.1093/jn/nxy095View ArticlePubMedPubMed Central
WHO (2018) Summary of WHO prequalification assessment for SD BIOLINE Malaria Ag P. f/P. f/P. v. Public Report, vol 2. WHO
Trape JF (1985) Rapid evaluation of malaria parasite density and standardization of thick smear examination for epidemiological investigations. Trans R Soc Trop Med Hyg 79(2):181–184. https://doi.org/10.1016/0035-9203(85)90329-3View ArticlePubMed
Erhardt JG, Estes JE, Pfeiffer CM, Biesalski HK, Craft NE (2004) Combined measurement of ferritin, soluble transferrin receptor, retinol binding protein, and C-reactive protein by an inexpensive, sensitive, and simple sandwich enzyme-linked immunosorbent assay technique. J Nutr 134(11):3127–3132View ArticlePubMed
WHO (2006) WHO Child Growth Standards: Length/height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age: methods and development
Kennedy G, Ballard T, Dop MC (2011) Guidelines for measuring household and individual dietary diversity. Food and Agriculture Organization of the United Nations
Agence Nationale de Sécurité Sanitaire de l’aliment de l’environnement et du travail France (2021) Les références nutritionnelles en vitamines et minéraux
Vyas S, Kumaranayake L (2006) Constructing socio-economic status indices: how to use principal components analysis. Health Policy Plan 21(6):459–468. https://doi.org/10.1093/heapol/czl029View ArticlePubMed
Thurnham DI, McCabe LD, Haldar S, Wieringa FT, Northrop-Clewes CA, McCabe GP (2010) Adjusting plasma ferritin concentrations to remove the effects of subclinical inflammation in the assessment of iron deficiency: a meta-analysis. Am J Clin Nutr 92(3):546–555. https://doi.org/10.3945/ajcn.2010.29284View ArticlePubMed
Alouache A, Hamma AS, Zenia S, Benlatreche C (2017) Statut et apports en vitamine A d’un échantillon de jeunes enfants Algériens. Cahiers de Nutrition et de Diététique 52(2):100–105View Article
Kere M, Millogo V, Schwab B, Massandjo H, Barro A, Harrigan T, Winter-Nelson A, Burdick R, Ouedraogo GA, Srivastava A (2020) Household food consumption profile of maize farmers in rural areas: Burkina Faso’s Hauts-Bassins region case. Int J Innov Appl Stud 30(2):667–687
Nana CP, Brouwer ID, Zagré NM, Kok FJ, Traoré AS (2005) Community assessment of availability, consumption, and cultural acceptability of food sources of (pro)vitamin A: toward the development of a dietary intervention among preschool children in rural Burkina Faso. Food Nutr Bull 26(4):356–365. https://doi.org/10.1177/156482650502600405View ArticlePubMed
Tanumihardjo SA (2002) Factors influencing the conversion of carotenoids to retinol: bioavailability to bioconversion to bioefficacy. Int J Vitam Nutr Res 72(1):40–45. https://doi.org/10.1024/0300-9831.72.1.40View ArticlePubMed
Haskell MJ, Jamil KM, Hassan F, Peerson JM, Hossain MI, Fuchs GJ, Brown KH (2004) Daily consumption of Indian spinach (Basella alba) or sweet potatoes has a positive effect on total-body vitamin A stores in Bangladeshi men. Am J Clin Nutr 80(3):705–714. https://doi.org/10.1093/ajcn/80.3.705View ArticlePubMed
Krinsky NI, Beecher G, Burk R, Chan A, Erdman J, Jacob R, Jialal I, Kolonel L, Marshall J, Taylor Mayne P (2000) Dietary reference intakes for vitamin C, vitamin E, selenium, and carotenoids. Inst Med 19:95–185
Wageesha ND, Ekanayake S, Jansz ER, Lamabadusuriya S (2011) Studies on hypercarotenemia due to excessive ingestion of carrot, pumpkin and papaw. Int J Food Sci Nutr 62(1):20–25. https://doi.org/10.3109/09637486.2010.511164View ArticlePubMed
Rankins J, Green NR, Tremper W, Stacewitcz-Sapuntzakis M, Bowen P, Ndiaye M (1993) Undernutrition and vitamin A deficiency in the Department of Linguère, Louga Region of Sénégal. Am J Clin Nutr 58(1):91–97. https://doi.org/10.1093/ajcn/58.1.91View ArticlePubMed
Gamble MV, Palafox NA, Dancheck B, Ricks MO, Briand K, Semba RD (2004) Carotenoid status among preschool children with vitamin A deficiency in the Republic of the Marshall Islands. Asia Pac J Clin Nutr 13(4):336–340PubMed
FAO (2018) Dietary assessment, A resource guide to method selection and application in low resource settings. FAO, Rome, p 152
Böhm V, Lietz G, Olmedilla-Alonso B, Phelan D, Reboul E, Bánati D, Borel P, Corte-Real J, de Lera AR, Desmarchelier C et al (2021) From carotenoid intake to carotenoid blood and tissue concentrations - implications for dietary intake recommendations. Nutr Rev 79(5):544–573. https://doi.org/10.1093/nutrit/nuaa008View ArticlePubMed
Okuda M, Sasaki S, Bando N, Hashimoto M, Kunitsugu I, Sugiyama S, Terao J, Hobara T (2009) Carotenoid, tocopherol, and fatty acid biomarkers and dietary intake estimated by using a brief self-administered diet history questionnaire for older Japanese children and adolescents. J Nutr Sci Vitaminol (Tokyo) 55(3):231–241. https://doi.org/10.3177/jnsv.55.231View ArticlePubMed
Semba RD, de Pee S, Sun K, Campbell AA, Bloem MW, Raju VK (2010) Low intake of vitamin A-rich foods among children, aged 12–35 months, in India: association with malnutrition, anemia, and missed child survival interventions. Nutrition 26(10):958–962. https://doi.org/10.1016/j.nut.2009.08.010View ArticlePubMed
Michaud DS, Giovannucci EL, Ascherio A, Rimm EB, Forman MR, Sampson L, Willett WC (1998) Associations of plasma carotenoid concentrations and dietary intake of specific carotenoids in samples of two prospective cohort studies using a new carotenoid database. Cancer Epidemiol Biomark Prev 7(4):283–290
Burrows TL, Williams R, Rollo M, Wood L, Garg ML, Jensen M, Collins CE (2015) Plasma carotenoid levels as biomarkers of dietary carotenoid consumption: A systematic review of the validation studies. J Nutr Intermed Metab 2(1–2):15–64View Article

Title: Dietary intake of preformed vitamin A and provitamin A carotenoids are not associated with serum retinol and carotenoid concentrations among children 36–59 months of age in rural Burkina Faso: a cross-sectional study
Authors: Olivier O. Sombié
Augustin N. Zeba
Jérome W. Somé
Adama Kazienga
Jeoffray Diendere
Jean F. Bationo
Christopher Davis
Michael Grahn
Sherry Tanumihardjo
Stefaan De Henauw
Souheila Abbeddou
Publication date: 17-08-2023
Publisher: Springer Berlin Heidelberg
Keyword: Malaria
Published in: European Journal of Nutrition / Issue 8/2023
Print ISSN: 1436-6207
Electronic ISSN: 1436-6215
DOI: https://doi.org/10.1007/s00394-023-03194-w

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