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European Journal of Nutrition
Published in: European Journal of Nutrition 5/2011

01-08-2011 | Original Contribution

Vitamin D deficiency is an independent predictor of elevated triglycerides in Spanish school children

Authors: Elena Rodríguez-Rodríguez, Rosa M. Ortega, Liliana G. González-Rodríguez, Ana M. López-Sobaler, UCM Research Group VALORNUT (920030)

Published in: European Journal of Nutrition | Issue 5/2011

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Abstract

Purpose

To determine the association between vitamin D status and the serum lipid profile in children.

Methods

The subjects of this cross-sectional study were 149 Spanish school children (8–13 years of age). The anthropometric data collected were weight and height, from which the body mass index (BMI) was calculated. Serum 25(OH)D concentrations were measured by chemiluminescent assay. Triglycerides were determined by enzyme colorimetry; total cholesterol and HDL-cholesterol were determined by the cholesterol esterase method. The LDL-cholesterol concentrations were determined mathematically.

Results

Compared to children with serum 25(OH)D concentrations in the fourth quartile, those in the first had higher triglyceride (86.0 ± 35.7 vs. 64.1 ± 26.7 mg/dL; p < 0.05). After adjusting for age, sex, BMI, and physical activity, the serum 25(OH)D level was found to be inversely proportional to the triglyceride (r = −0.857; p = 0.010). While age, sex, BMI, and physical activity explained 12% of the variance of the HDL-cholesterol figures, the inclusion of serum 25(OH)D allowed 23% of the variance to be explained.

Conclusion

A low serum vitamin D levels in children is associated with high triglyceride levels.
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Metadata
Title
Vitamin D deficiency is an independent predictor of elevated triglycerides in Spanish school children
Authors
Elena Rodríguez-Rodríguez
Rosa M. Ortega
Liliana G. González-Rodríguez
Ana M. López-Sobaler
UCM Research Group VALORNUT (920030)
Publication date
01-08-2011
Publisher
Springer-Verlag
Published in
European Journal of Nutrition / Issue 5/2011
Print ISSN: 1436-6207
Electronic ISSN: 1436-6215
DOI
https://doi.org/10.1007/s00394-010-0145-4

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