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Published in: Clinical Research in Cardiology 3/2020

Open Access 01-03-2020 | Myocardial Infarction | Original Paper

Predictors of transportation delay in patients with suspected ST-elevation-myocardial infarction in the VIENNA-STEMI network

Authors: Bernhard Jäger, Paul Michael Haller, Edita Piackova, Alfred Kaff, Günter Christ, Wolfgang Schreiber, Franz Weidinger, Thomas Stefenelli, Georg Delle-Karth, Gerhard Maurer, Kurt Huber, for the Vienna STEMI Registry Group

Published in: Clinical Research in Cardiology | Issue 3/2020

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Abstract

Objective

The emergency medical service (EMS) provides rapid pre-hospital diagnosis and transportation in ST-elevation myocardial infarction (STEMI) systems of care. Aim of the study was to assess temporal and regional characteristics of EMS-related delays in a metropolitan STEMI network.

Methods

Patient call-to-arrival of EMS at site (call-to-site), transportation time from site to hospital (site-to-door), call-to-door, patient’s location, month, weekday, and hour of EMS activation were recorded in 4751 patients referred to a tertiary center with suspicion of STEMI.

Results

Median call-to-site, site-to-door, and call-to-door times were 9 (7–12), 39 (31–48), and 49 (41–59) minutes, respectively. The shortest transportation times were noted between 08:00 and 16:00 and in general on Sundays. They were significantly prolonged between midnight and 04:00, whereby the longest difference did not exceed 4 min in median. Patient’s site of call had a major impact on transportation times, which were shorter in Central and Western districts as compared to Southern and Eastern districts of Vienna (p < 0.001 between-group difference for call-to-site, site-to-door, and call-to-door). After multivariable adjustment, patient’s site of call was an independent predictor of call-to-site delay (p < 0.001). Moreover, age and hour of EMS activation were the strongest predictors of call-to-site, site-to-door, and call-to-door delays (p < 0.05).

Conclusion

In our Viennese STEMI network, the strongest determinants of pre-hospital EMS-related transportation delays were patient’s site of call, patient’s age, and hour of EMS activation. Due to the significant but small median time delays, which are within the guideline-recommended time intervals, no impact on clinical outcome can be expected.

Graphic abstract

Literature
1.
go back to reference Ibanez B, James S, Agewall S, Antunes MJ, Bucciarelli-Ducci C, Bueno H, Caforio ALP, Crea F, Goudevenos JA, Halvorsen S, Hindricks G, Kastrati A, Lenzen MJ, Prescott E, Roffi M, Valgimigli M, Varenhorst C, Vranckx P, Widimsky P (2017) 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: the task force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J 15:15. https://doi.org/10.1093/eurheartj/ehx393 CrossRef Ibanez B, James S, Agewall S, Antunes MJ, Bucciarelli-Ducci C, Bueno H, Caforio ALP, Crea F, Goudevenos JA, Halvorsen S, Hindricks G, Kastrati A, Lenzen MJ, Prescott E, Roffi M, Valgimigli M, Varenhorst C, Vranckx P, Widimsky P (2017) 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: the task force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J 15:15. https://​doi.​org/​10.​1093/​eurheartj/​ehx393 CrossRef
5.
go back to reference Knot J, Widimsky P, Wijns W, Stenestrand U, Kristensen SD, Van THA, Weidinger F, Janzon M, Norgaard BL, Soerensen JT, van de Wetering H, Thygesen K, Bergsten PA, Digerfeldt C, Potgieter A, Tomer N, Fajadet J (2009) How to set up an effective national primary angioplasty network: lessons learned from five European countries. EuroIntervention 5(3):301–309 Knot J, Widimsky P, Wijns W, Stenestrand U, Kristensen SD, Van THA, Weidinger F, Janzon M, Norgaard BL, Soerensen JT, van de Wetering H, Thygesen K, Bergsten PA, Digerfeldt C, Potgieter A, Tomer N, Fajadet J (2009) How to set up an effective national primary angioplasty network: lessons learned from five European countries. EuroIntervention 5(3):301–309
7.
go back to reference Sorensen JT, Terkelsen CJ, Norgaard BL, Trautner S, Hansen TM, Botker HE, Lassen JF, Andersen HR (2011) Urban and rural implementation of pre-hospital diagnosis and direct referral for primary percutaneous coronary intervention in patients with acute ST-elevation myocardial infarction. Eur Heart J 32(4):430–436. https://doi.org/10.1093/eurheartj/ehq437 CrossRefPubMed Sorensen JT, Terkelsen CJ, Norgaard BL, Trautner S, Hansen TM, Botker HE, Lassen JF, Andersen HR (2011) Urban and rural implementation of pre-hospital diagnosis and direct referral for primary percutaneous coronary intervention in patients with acute ST-elevation myocardial infarction. Eur Heart J 32(4):430–436. https://​doi.​org/​10.​1093/​eurheartj/​ehq437 CrossRefPubMed
11.
go back to reference Jager B, Farhan S, Rohla M, Christ G, Podczeck-Schweighofer A, Schreiber W, Laggner AN, Weidinger F, Stefenelli T, Delle-Karth G, Kaff A, Maurer G, Huber K, Vienna SRG (2016) Clinical predictors of patient related delay in the VIENNA ST-elevation myocardial infarction network and impact on long-term mortality. Eur Heart J Acute Cardiovasc Care. https://doi.org/10.1177/2048872616633882 CrossRefPubMed Jager B, Farhan S, Rohla M, Christ G, Podczeck-Schweighofer A, Schreiber W, Laggner AN, Weidinger F, Stefenelli T, Delle-Karth G, Kaff A, Maurer G, Huber K, Vienna SRG (2016) Clinical predictors of patient related delay in the VIENNA ST-elevation myocardial infarction network and impact on long-term mortality. Eur Heart J Acute Cardiovasc Care. https://​doi.​org/​10.​1177/​2048872616633882​ CrossRefPubMed
13.
go back to reference Kalla K, Christ G, Karnik R, Malzer R, Norman G, Prachar H, Schreiber W, Unger G, Glogar HD, Kaff A, Laggner AN, Maurer G, Mlczoch J, Slany J, Weber HS, Huber K, Vienna SRG (2006) Implementation of guidelines improves the standard of care: the Viennese registry on reperfusion strategies in ST-elevation myocardial infarction (Vienna STEMI registry). Circulation 113(20):2398–2405. https://doi.org/10.1161/CIRCULATIONAHA.105.586198 CrossRefPubMed Kalla K, Christ G, Karnik R, Malzer R, Norman G, Prachar H, Schreiber W, Unger G, Glogar HD, Kaff A, Laggner AN, Maurer G, Mlczoch J, Slany J, Weber HS, Huber K, Vienna SRG (2006) Implementation of guidelines improves the standard of care: the Viennese registry on reperfusion strategies in ST-elevation myocardial infarction (Vienna STEMI registry). Circulation 113(20):2398–2405. https://​doi.​org/​10.​1161/​CIRCULATIONAHA.​105.​586198 CrossRefPubMed
14.
go back to reference Armstrong PW, Gershlick AH, Goldstein P, Wilcox R, Danays T, Lambert Y, Sulimov V, Rosell Ortiz F, Ostojic M, Welsh RC, Carvalho AC, Nanas J, Arntz HR, Halvorsen S, Huber K, Grajek S, Fresco C, Bluhmki E, Regelin A, Vandenberghe K, Bogaerts K, Van de Werf F, Team SI (2013) Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction. N Engl J Med 368(15):1379–1387. https://doi.org/10.1056/NEJMoa1301092 CrossRefPubMed Armstrong PW, Gershlick AH, Goldstein P, Wilcox R, Danays T, Lambert Y, Sulimov V, Rosell Ortiz F, Ostojic M, Welsh RC, Carvalho AC, Nanas J, Arntz HR, Halvorsen S, Huber K, Grajek S, Fresco C, Bluhmki E, Regelin A, Vandenberghe K, Bogaerts K, Van de Werf F, Team SI (2013) Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction. N Engl J Med 368(15):1379–1387. https://​doi.​org/​10.​1056/​NEJMoa1301092 CrossRefPubMed
17.
go back to reference Fournier S, Muller O, Benedetto U, Roffi M, Pilgrim T, Eberli FR, Rickli H, Radovanovic D, Erne P, Cook S, Noble S, Fesselet R, Zuffi A, Degrauwe S, Masci P, Windecker S, Eeckhout E, Iglesias JF, on behalf on the API (2018) Circadian dependence of manual thrombus aspiration benefit in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. Clin Res Cardiol 107(4):338–346. https://doi.org/10.1007/s00392-017-1189-8 CrossRefPubMed Fournier S, Muller O, Benedetto U, Roffi M, Pilgrim T, Eberli FR, Rickli H, Radovanovic D, Erne P, Cook S, Noble S, Fesselet R, Zuffi A, Degrauwe S, Masci P, Windecker S, Eeckhout E, Iglesias JF, on behalf on the API (2018) Circadian dependence of manual thrombus aspiration benefit in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. Clin Res Cardiol 107(4):338–346. https://​doi.​org/​10.​1007/​s00392-017-1189-8 CrossRefPubMed
19.
go back to reference Chrusciel P, Goch A, Banach M, Mikhailidis DP, Rysz J, Goch JH (2009) Circadian changes in the hemostatic system in healthy men and patients with cardiovascular diseases. Med Sci Monit 15(10):RA203–RA208CrossRef Chrusciel P, Goch A, Banach M, Mikhailidis DP, Rysz J, Goch JH (2009) Circadian changes in the hemostatic system in healthy men and patients with cardiovascular diseases. Med Sci Monit 15(10):RA203–RA208CrossRef
20.
go back to reference Fromm RE Jr, Levine RL, Pepe PE (1992) Circadian variation in the time of request for helicopter transport of cardiac patients. Ann Emerg Med 21(10):1196–1199CrossRef Fromm RE Jr, Levine RL, Pepe PE (1992) Circadian variation in the time of request for helicopter transport of cardiac patients. Ann Emerg Med 21(10):1196–1199CrossRef
22.
go back to reference Batty M, Besussi E, Chin N (2003) Traffic, Urban Growth and Suburban Sprawl. UCL Centre for Advanced Spatial Analysis Working Papers Series 70. ISSN 1467-1298 Batty M, Besussi E, Chin N (2003) Traffic, Urban Growth and Suburban Sprawl. UCL Centre for Advanced Spatial Analysis Working Papers Series 70. ISSN 1467-1298
26.
go back to reference Backhaus T, Fach A, Schmucker J, Fiehn E, Garstka D, Stehmeier J, Hambrecht R, Wienbergen H (2018) Management and predictors of outcome in unselected patients with cardiogenic shock complicating acute ST-segment elevation myocardial infarction: results from the Bremen STEMI Registry. Clin Res Cardiol 107(5):371–379. https://doi.org/10.1007/s00392-017-1192-0 CrossRefPubMed Backhaus T, Fach A, Schmucker J, Fiehn E, Garstka D, Stehmeier J, Hambrecht R, Wienbergen H (2018) Management and predictors of outcome in unselected patients with cardiogenic shock complicating acute ST-segment elevation myocardial infarction: results from the Bremen STEMI Registry. Clin Res Cardiol 107(5):371–379. https://​doi.​org/​10.​1007/​s00392-017-1192-0 CrossRefPubMed
Metadata
Title
Predictors of transportation delay in patients with suspected ST-elevation-myocardial infarction in the VIENNA-STEMI network
Authors
Bernhard Jäger
Paul Michael Haller
Edita Piackova
Alfred Kaff
Günter Christ
Wolfgang Schreiber
Franz Weidinger
Thomas Stefenelli
Georg Delle-Karth
Gerhard Maurer
Kurt Huber
for the Vienna STEMI Registry Group
Publication date
01-03-2020
Publisher
Springer Berlin Heidelberg
Published in
Clinical Research in Cardiology / Issue 3/2020
Print ISSN: 1861-0684
Electronic ISSN: 1861-0692
DOI
https://doi.org/10.1007/s00392-019-01520-z

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