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01-05-2018 | Original Paper

Five-year clinical outcomes of visually guided laser balloon pulmonary vein isolation for the treatment of paroxysmal atrial fibrillation

Authors: Bruno Reissmann, Thorsten Budelmann, Erik Wissner, Michael Schlüter, Christian-Hendrik Heeger, Shibu Mathew, Tilman Maurer, Christine Lemes, Thomas Fink, Andreas Rillig, Francesco Santoro, Johannes Riedl, Feifan Ouyang, Karl-Heinz Kuck, Andreas Metzner

Published in: Clinical Research in Cardiology | Issue 5/2018

Abstract

Background

Visually guided laser balloon (VGLB) ablation allows for pulmonary vein isolation (PVI) under direct endoscopic control. Short- and midterm clinical outcomes are in accordance with results of radiofrequency current (RFC) ablation for the treatment of paroxysmal atrial fibrillation (PAF).

Objective

The current study sought to assess the long-term clinical outcomes of VGLB-based PVI for PAF.

Methods

A total of 90 patients [60 ± 10 years; 33 (37%) female, left atrial diameter 42 ± 4 mm] with drug-refractory PAF underwent VGLB ablation. The median duration of PAF until VGLB ablation was 36 (interquartile range 12; 84) months. Follow-up was based on outpatient clinic visits including Holter ECGs and telephone interviews. Repeat ablation due to arrhythmia recurrences was performed using RFC ablation.

Results

After a single VGLB procedure, 5-year freedom from arrhythmia recurrence was 51% [95% confidence interval (CI) 39–62%]. Thirty-three patients underwent repeat RFC ablation procedures, resulting in multiple procedure freedom from arrhythmia recurrence of 78% (95% CI 68–88%). Major periprocedural complications occurred in four patients (4%).

Conclusions

VGLB ablation for the treatment of drug-refractory PAF is safe and results in 5-year single and multiple procedure arrhythmia-free survival of 51 and 78%, respectively.

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Title: Five-year clinical outcomes of visually guided laser balloon pulmonary vein isolation for the treatment of paroxysmal atrial fibrillation
Authors: Bruno Reissmann
Thorsten Budelmann
Erik Wissner
Michael Schlüter
Christian-Hendrik Heeger
Shibu Mathew
Tilman Maurer
Christine Lemes
Thomas Fink
Andreas Rillig
Francesco Santoro
Johannes Riedl
Feifan Ouyang
Karl-Heinz Kuck
Andreas Metzner
Publication date: 01-05-2018
Publisher: Springer Berlin Heidelberg
Published in: Clinical Research in Cardiology / Issue 5/2018
Print ISSN: 1861-0684
Electronic ISSN: 1861-0692
DOI: https://doi.org/10.1007/s00392-017-1199-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Five-year clinical outcomes of visually guided laser balloon pulmonary vein isolation for the treatment of paroxysmal atrial fibrillation

Abstract

Background

Objective

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Objective

Methods

Results

Conclusions

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