Skip to main content
Top
Published in: International Journal of Colorectal Disease 3/2016

01-03-2016 | Original Article

Robot-assisted surgery for the radical treatment of deep infiltrating endometriosis with colorectal involvement: short- and mid-term surgical and functional outcomes

Authors: Luca Morelli, Alessandra Perutelli, Matteo Palmeri, Simone Guadagni, Maria Donatella Mariniello, Gregorio Di Franco, Vito Cela, Benedetta Brundu, Maria Giovanna Salerno, Giulio Di Candio, Franco Mosca

Published in: International Journal of Colorectal Disease | Issue 3/2016

Login to get access

Abstract

Purpose

Sexual and urinary dysfunctions are complications in radical treatment of deep infiltrating endometriosis (DIE) with colorectal involvement. The aim of this article is to report the preliminary results of our single-institution experience with robotic treatment of DIE, evaluating intraoperative and postoperative surgical outcomes and focusing on the impact of this surgical approach on autonomic functions such as urogenital preservation and sexual well-being.

Methods

From January 2011 through December 2013, a case series of 10 patients underwent robotic radical treatment of DIE with colorectal resection using the da Vinci System. Surgical data were evaluated, together with perioperative urinary and sexual function as assessed by means of self-administered validated questionnaires.

Results

None of the patients reported significant postoperative complications. Questionnaires concerning sexual well-being, urinary function, and impact of symptoms on quality of life demonstrated a slight worsening of all parameters 1 month after surgery, while data were comparable to the preoperative period 1 year after surgery. Dyspareunia was the only exception, as it was significantly improved 12 months after surgery.

Conclusions

Robot-assisted surgery seems to be advantageous in highly complicated procedures where extensive dissection and proper anatomy re-establishment is required, as in DIE with colorectal involvement. Our preliminary results show that robot-assisted surgery could be associated with a low risk of complications and provide good preservation of urinary function and sexual well-being.
Literature
1.
go back to reference Kennedy S, Bergqvist A, Chapron C, D’Hooghe T, Dunselman G, Greb R, Hummelshoj L, Prentice A, Saridogan E, E.S.I.G.f. Endometriosis, and G. Endometrium Guideline Development (2005) ESHRE guideline for the diagnosis and treatment of endometriosis. Hum Reprod 20(10):2698–2704CrossRefPubMed Kennedy S, Bergqvist A, Chapron C, D’Hooghe T, Dunselman G, Greb R, Hummelshoj L, Prentice A, Saridogan E, E.S.I.G.f. Endometriosis, and G. Endometrium Guideline Development (2005) ESHRE guideline for the diagnosis and treatment of endometriosis. Hum Reprod 20(10):2698–2704CrossRefPubMed
2.
go back to reference Giudice LC, S.L., Burney RO, Endometriosis. In: Jameson Jl, De Groot LJ, eds. 6th ed, ed. Endocrinology. 2010, New York: Elsevier. Giudice LC, S.L., Burney RO, Endometriosis. In: Jameson Jl, De Groot LJ, eds. 6th ed, ed. Endocrinology. 2010, New York: Elsevier.
3.
go back to reference Ballweg ML (2004) Impact of endometriosis on women’s health: comparative historical data show that the earlier the onset, the more severe the disease. Best Pract Res Clin Obstet Gynaecol 18(2):201–218CrossRefPubMed Ballweg ML (2004) Impact of endometriosis on women’s health: comparative historical data show that the earlier the onset, the more severe the disease. Best Pract Res Clin Obstet Gynaecol 18(2):201–218CrossRefPubMed
4.
go back to reference Garry R, Clayton R, Hawe J (2000) The effect of endometriosis and its radical laparoscopic excision on quality of life indicators. Bjog 107(1):44–54CrossRefPubMed Garry R, Clayton R, Hawe J (2000) The effect of endometriosis and its radical laparoscopic excision on quality of life indicators. Bjog 107(1):44–54CrossRefPubMed
5.
go back to reference Redwine DB, Wright JT (2001) Laparoscopic treatment of complete obliteration of the cul-de-sac associated with endometriosis: long-term follow-up of en bloc resection. Fertil Steril 76(2):358–365CrossRefPubMed Redwine DB, Wright JT (2001) Laparoscopic treatment of complete obliteration of the cul-de-sac associated with endometriosis: long-term follow-up of en bloc resection. Fertil Steril 76(2):358–365CrossRefPubMed
6.
go back to reference Neme RM, Schraibman V, Okazaki S, Maccapani G, Chen WJ, Domit CD, Kaufmann OG, Advincula AP (2013) Deep infiltrating colorectal endometriosis treated with robotic-assisted rectosigmoidectomy. Jsls 17(2):227–234CrossRefPubMedPubMedCentral Neme RM, Schraibman V, Okazaki S, Maccapani G, Chen WJ, Domit CD, Kaufmann OG, Advincula AP (2013) Deep infiltrating colorectal endometriosis treated with robotic-assisted rectosigmoidectomy. Jsls 17(2):227–234CrossRefPubMedPubMedCentral
7.
go back to reference Vitobello D, Fattizzi N, Santoro G, Rosati R, Baldazzi G, Bulletti C, Palmara V (2013) Robotic surgery and standard laparoscopy: a surgical hybrid technique for use in colorectal endometriosis. J Obstet Gynaecol Res 39(1):217–222CrossRefPubMed Vitobello D, Fattizzi N, Santoro G, Rosati R, Baldazzi G, Bulletti C, Palmara V (2013) Robotic surgery and standard laparoscopy: a surgical hybrid technique for use in colorectal endometriosis. J Obstet Gynaecol Res 39(1):217–222CrossRefPubMed
8.
go back to reference Siesto G, Ieda N, Rosati R, Vitobello D (2014) Robotic surgery for deep endometriosis: a paradigm shift. Int J Med Robot 10(2):140–146CrossRefPubMed Siesto G, Ieda N, Rosati R, Vitobello D (2014) Robotic surgery for deep endometriosis: a paradigm shift. Int J Med Robot 10(2):140–146CrossRefPubMed
9.
go back to reference Bianchi PP, Rosati R, Bona S, Rottoli M, Elmore U, Ceriani C, Malesci A, Montorsi M (2007) Laparoscopic surgery in rectal cancer: a prospective analysis of patient survival and outcomes. Dis Colon Rectum 50(12):2047–2053CrossRefPubMed Bianchi PP, Rosati R, Bona S, Rottoli M, Elmore U, Ceriani C, Malesci A, Montorsi M (2007) Laparoscopic surgery in rectal cancer: a prospective analysis of patient survival and outcomes. Dis Colon Rectum 50(12):2047–2053CrossRefPubMed
10.
go back to reference Kondo W, Ribeiro R, Trippia C, Zomer MT (2013) Laparoscopic treatment of deep infiltrating endometriosis affecting the rectosigmoid colon: nodulectomy or segmental resection? Gynecol Obstetric S3:001. doi:10.4172/2161-0932.S3-001 Kondo W, Ribeiro R, Trippia C, Zomer MT (2013) Laparoscopic treatment of deep infiltrating endometriosis affecting the rectosigmoid colon: nodulectomy or segmental resection? Gynecol Obstetric S3:001. doi:10.​4172/​2161-0932.​S3-001
11.
go back to reference Coelho RF, Chauhan S, Palmer KJ, Rocco B, Patel MB, Patel VR (2009) Robotic-assisted radical prostatectomy: a review of current outcomes. BJU Int 104(10):1428–1435CrossRefPubMed Coelho RF, Chauhan S, Palmer KJ, Rocco B, Patel MB, Patel VR (2009) Robotic-assisted radical prostatectomy: a review of current outcomes. BJU Int 104(10):1428–1435CrossRefPubMed
12.
go back to reference Ercoli A, D’Asta M, Fagotti A, Fanfani F, Romano F, Baldazzi G, Salerno MG, Scambia G (2012) Robotic treatment of colorectal endometriosis: technique, feasibility and short-term results. Hum Reprod 27(3):722–726CrossRefPubMed Ercoli A, D’Asta M, Fagotti A, Fanfani F, Romano F, Baldazzi G, Salerno MG, Scambia G (2012) Robotic treatment of colorectal endometriosis: technique, feasibility and short-term results. Hum Reprod 27(3):722–726CrossRefPubMed
13.
go back to reference Baik SH, Kwon HY, Kim JS, Hur H, Sohn SK, Cho CH, Kim H (2009) Robotic versus laparoscopic low anterior resection of rectal cancer: short-term outcome of a prospective comparative study. Ann Surg Oncol 16(6):1480–1487CrossRefPubMed Baik SH, Kwon HY, Kim JS, Hur H, Sohn SK, Cho CH, Kim H (2009) Robotic versus laparoscopic low anterior resection of rectal cancer: short-term outcome of a prospective comparative study. Ann Surg Oncol 16(6):1480–1487CrossRefPubMed
14.
go back to reference Luca F, Valvo M, Ghezzi TL, Zuccaro M, Cenciarelli S, Trovato C, Sonzogni A, Biffi R (2013) Impact of robotic surgery on sexual and urinary functions after fully robotic nerve-sparing total mesorectal excision for rectal cancer. Ann Surg 257(4):672–678CrossRefPubMed Luca F, Valvo M, Ghezzi TL, Zuccaro M, Cenciarelli S, Trovato C, Sonzogni A, Biffi R (2013) Impact of robotic surgery on sexual and urinary functions after fully robotic nerve-sparing total mesorectal excision for rectal cancer. Ann Surg 257(4):672–678CrossRefPubMed
15.
go back to reference Kim JY, Kim NK, Lee KY, Hur H, Min BS, Kim JH (2012) A comparative study of voiding and sexual function after total mesorectal excision with autonomic nerve preservation for rectal cancer: laparoscopic versus robotic surgery. Ann Surg Oncol 19(8):2485–2493CrossRefPubMed Kim JY, Kim NK, Lee KY, Hur H, Min BS, Kim JH (2012) A comparative study of voiding and sexual function after total mesorectal excision with autonomic nerve preservation for rectal cancer: laparoscopic versus robotic surgery. Ann Surg Oncol 19(8):2485–2493CrossRefPubMed
16.
go back to reference D’Annibale A, Pernazza G, Monsellato I, Pende V, Lucandri G, Mazzocchi P, Alfano G (2013) Total mesorectal excision: a comparison of oncological and functional outcomes between robotic and laparoscopic surgery for rectal cancer. Surg Endosc 27(6):1887–1895CrossRefPubMed D’Annibale A, Pernazza G, Monsellato I, Pende V, Lucandri G, Mazzocchi P, Alfano G (2013) Total mesorectal excision: a comparison of oncological and functional outcomes between robotic and laparoscopic surgery for rectal cancer. Surg Endosc 27(6):1887–1895CrossRefPubMed
17.
go back to reference Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240(2):205–213CrossRefPubMedPubMedCentral Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240(2):205–213CrossRefPubMedPubMedCentral
19.
go back to reference Rosen R, Brown C, Heiman J, Leiblum S, Meston C, Shabsigh R, Ferguson D, D’Agostino R Jr (2000) The Female Sexual Function Index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function. J Sex Marital Ther 26(2):191–208CrossRefPubMed Rosen R, Brown C, Heiman J, Leiblum S, Meston C, Shabsigh R, Ferguson D, D’Agostino R Jr (2000) The Female Sexual Function Index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function. J Sex Marital Ther 26(2):191–208CrossRefPubMed
20.
go back to reference Lim P, Kang E, Park D (2011) Robot-assisted total intracorporeal low anterior resection with primary anastomosis and radical dissection for treatment of stage IV endometriosis with bowel involvement: morbidity and its outcome. J Robot Surg 5(4):273–278CrossRef Lim P, Kang E, Park D (2011) Robot-assisted total intracorporeal low anterior resection with primary anastomosis and radical dissection for treatment of stage IV endometriosis with bowel involvement: morbidity and its outcome. J Robot Surg 5(4):273–278CrossRef
21.
go back to reference Roman H, Vassilieff M, Gourcerol G, Savoye G, Leroi AM, Marpeau L, Michot F, Tuech JJ (2011) Surgical management of deep infiltrating endometriosis of the rectum: pleading for a symptom-guided approach. Hum Reprod 26(2):274–281CrossRefPubMed Roman H, Vassilieff M, Gourcerol G, Savoye G, Leroi AM, Marpeau L, Michot F, Tuech JJ (2011) Surgical management of deep infiltrating endometriosis of the rectum: pleading for a symptom-guided approach. Hum Reprod 26(2):274–281CrossRefPubMed
22.
23.
go back to reference Mak TW, Lee JF, Futaba K, Hon SS, Ngo DK, Ng SS (2014) Robotic surgery for rectal cancer: a systematic review of current practice. World J Gastrointest Oncol 6(6):184–193PubMedPubMedCentral Mak TW, Lee JF, Futaba K, Hon SS, Ngo DK, Ng SS (2014) Robotic surgery for rectal cancer: a systematic review of current practice. World J Gastrointest Oncol 6(6):184–193PubMedPubMedCentral
24.
go back to reference Park EJ, Cho MS, Baek SJ, Hur H, Min BS, Baik SH, Lee KY, Kim NK (2015) Long-term oncologic outcomes of robotic low anterior resection for rectal cancer: a comparative study with laparoscopic surgery. Ann Surg 261(1):129–137CrossRefPubMed Park EJ, Cho MS, Baek SJ, Hur H, Min BS, Baik SH, Lee KY, Kim NK (2015) Long-term oncologic outcomes of robotic low anterior resection for rectal cancer: a comparative study with laparoscopic surgery. Ann Surg 261(1):129–137CrossRefPubMed
25.
go back to reference Baek SJ, Al-Asari S, Jeong DH, Hur H, Min BS, Baik SH, Kim NK (2013) Robotic versus laparoscopic coloanal anastomosis with or without intersphincteric resection for rectal cancer. Surg Endosc 27(11):4157–4163CrossRefPubMed Baek SJ, Al-Asari S, Jeong DH, Hur H, Min BS, Baik SH, Kim NK (2013) Robotic versus laparoscopic coloanal anastomosis with or without intersphincteric resection for rectal cancer. Surg Endosc 27(11):4157–4163CrossRefPubMed
26.
go back to reference Shiomi A, Kinugasa Y, Yamaguchi T, Tomioka H, Kagawa H (2014) Robot-assisted rectal cancer surgery: short-term outcomes for 113 consecutive patients. Int J Colorectal Dis 29(9):1105–1111CrossRefPubMed Shiomi A, Kinugasa Y, Yamaguchi T, Tomioka H, Kagawa H (2014) Robot-assisted rectal cancer surgery: short-term outcomes for 113 consecutive patients. Int J Colorectal Dis 29(9):1105–1111CrossRefPubMed
27.
go back to reference Kim CW, Kim CH, Baik SH (2014) Outcomes of robotic-assisted colorectal surgery compared with laparoscopic and open surgery: a systematic review. J Gastrointest Surg 18(4):816–830CrossRefPubMed Kim CW, Kim CH, Baik SH (2014) Outcomes of robotic-assisted colorectal surgery compared with laparoscopic and open surgery: a systematic review. J Gastrointest Surg 18(4):816–830CrossRefPubMed
28.
go back to reference Papanikolaou IG (2014) Robotic surgery for colorectal cancer: systematic review of the literature. Surg Laparosc Endosc Percutan Tech 24(6):478–483PubMed Papanikolaou IG (2014) Robotic surgery for colorectal cancer: systematic review of the literature. Surg Laparosc Endosc Percutan Tech 24(6):478–483PubMed
29.
go back to reference Tan SJ, Lin CK, Fu PT, Liu YL, Sun CC, Chang CC, Yu MH, Lai HC (2012) Robotic surgery in complicated gynecologic diseases: experience of Tri-Service General Hospital in Taiwan. Taiwan J Obstet Gynecol 51(1):18–25CrossRefPubMed Tan SJ, Lin CK, Fu PT, Liu YL, Sun CC, Chang CC, Yu MH, Lai HC (2012) Robotic surgery in complicated gynecologic diseases: experience of Tri-Service General Hospital in Taiwan. Taiwan J Obstet Gynecol 51(1):18–25CrossRefPubMed
30.
go back to reference Antoniou SA, Antoniou GA, Koch OO, Pointner R, Granderath FA (2012) Robot-assisted laparoscopic surgery of the colon and rectum. Surg Endosc 26(1):1–11CrossRefPubMed Antoniou SA, Antoniou GA, Koch OO, Pointner R, Granderath FA (2012) Robot-assisted laparoscopic surgery of the colon and rectum. Surg Endosc 26(1):1–11CrossRefPubMed
31.
go back to reference Nezhat C, Modest AM, King LP (2013) The role of the robot in treating urinary tract endometriosis. Curr Opin Obstet Gynecol 25(4):308–311CrossRefPubMed Nezhat C, Modest AM, King LP (2013) The role of the robot in treating urinary tract endometriosis. Curr Opin Obstet Gynecol 25(4):308–311CrossRefPubMed
32.
go back to reference Liu C, Perisic D, Samadi D, Nezhat F (2008) Robotic-assisted laparoscopic partial bladder resection for the treatment of infiltrating endometriosis. J Minim Invasive Gynecol 15(6):745–748CrossRefPubMed Liu C, Perisic D, Samadi D, Nezhat F (2008) Robotic-assisted laparoscopic partial bladder resection for the treatment of infiltrating endometriosis. J Minim Invasive Gynecol 15(6):745–748CrossRefPubMed
33.
go back to reference Patel VR, Patil NN, Coughlin G, Dangle PP, Palmer K (2008) Robot-assisted laparoscopic pyeloplasty: a review of minimally invasive treatment options for ureteropelvic junction obstruction. J Robot Surg 1(4):247–252CrossRefPubMedPubMedCentral Patel VR, Patil NN, Coughlin G, Dangle PP, Palmer K (2008) Robot-assisted laparoscopic pyeloplasty: a review of minimally invasive treatment options for ureteropelvic junction obstruction. J Robot Surg 1(4):247–252CrossRefPubMedPubMedCentral
34.
go back to reference Ghezzi TL, Luca F, Valvo M, Corleta OC, Zuccaro M, Cenciarelli S, Biffi R (2014) Robotic versus open total mesorectal excision for rectal cancer: comparative study of short and long-term outcomes. Eur J Surg Oncol 40(9):1072–1079CrossRefPubMed Ghezzi TL, Luca F, Valvo M, Corleta OC, Zuccaro M, Cenciarelli S, Biffi R (2014) Robotic versus open total mesorectal excision for rectal cancer: comparative study of short and long-term outcomes. Eur J Surg Oncol 40(9):1072–1079CrossRefPubMed
35.
go back to reference Park SY, Choi GS, Park JS, Kim HJ, Ryuk JP (2013) Short-term clinical outcome of robot-assisted intersphincteric resection for low rectal cancer: a retrospective comparison with conventional laparoscopy. Surg Endosc 27(1):48–55CrossRefPubMed Park SY, Choi GS, Park JS, Kim HJ, Ryuk JP (2013) Short-term clinical outcome of robot-assisted intersphincteric resection for low rectal cancer: a retrospective comparison with conventional laparoscopy. Surg Endosc 27(1):48–55CrossRefPubMed
36.
go back to reference Darai E, Bazot M, Rouzier R, Coutant C, Ballester M (2008) Colorectal endometriosis and fertility. Gynecol Obstet Fertil 36(12):1214–1217CrossRefPubMed Darai E, Bazot M, Rouzier R, Coutant C, Ballester M (2008) Colorectal endometriosis and fertility. Gynecol Obstet Fertil 36(12):1214–1217CrossRefPubMed
37.
go back to reference Collinet P, Leguevaque P, Neme RM, Cela V, Barton-Smith P, Hebert T, Hanssens S, Nishi H, Nisolle M (2014) Robot-assisted laparoscopy for deep infiltrating endometriosis: international multicentric retrospective study. Surg Endosc 28(8):2474–2479CrossRefPubMed Collinet P, Leguevaque P, Neme RM, Cela V, Barton-Smith P, Hebert T, Hanssens S, Nishi H, Nisolle M (2014) Robot-assisted laparoscopy for deep infiltrating endometriosis: international multicentric retrospective study. Surg Endosc 28(8):2474–2479CrossRefPubMed
38.
go back to reference Carbonnel M, Goetgheluck J, Frati A, Even M, Ayoubi JM (2014) Robot-assisted laparoscopy for infertility treatment: current views. Fertil Steril 101(3):621–626CrossRefPubMed Carbonnel M, Goetgheluck J, Frati A, Even M, Ayoubi JM (2014) Robot-assisted laparoscopy for infertility treatment: current views. Fertil Steril 101(3):621–626CrossRefPubMed
39.
go back to reference Byrn JC, Hrabe JE, Charlton ME (2014) An initial experience with 85 consecutive robotic-assisted rectal dissections: improved operating times and lower costs with experience. Surg Endosc 28(11):3101–3107CrossRefPubMedPubMedCentral Byrn JC, Hrabe JE, Charlton ME (2014) An initial experience with 85 consecutive robotic-assisted rectal dissections: improved operating times and lower costs with experience. Surg Endosc 28(11):3101–3107CrossRefPubMedPubMedCentral
40.
go back to reference Meuleman C, Tomassetti C, D’Hoore A, Van Cleynenbreugel B, Penninckx F, Vergote I, D’Hooghe T (2011) Surgical treatment of deeply infiltrating endometriosis with colorectal involvement. Hum Reprod Update 17(3):311–326CrossRefPubMed Meuleman C, Tomassetti C, D’Hoore A, Van Cleynenbreugel B, Penninckx F, Vergote I, D’Hooghe T (2011) Surgical treatment of deeply infiltrating endometriosis with colorectal involvement. Hum Reprod Update 17(3):311–326CrossRefPubMed
41.
go back to reference Bianchi PP, Luca F, Petz W, Valvo M, Cenciarelli S, Zuccaro M, Biffi R (2013) The role of the robotic technique in minimally invasive surgery in rectal cancer. Ecancermedicalscience 7:357PubMedPubMedCentral Bianchi PP, Luca F, Petz W, Valvo M, Cenciarelli S, Zuccaro M, Biffi R (2013) The role of the robotic technique in minimally invasive surgery in rectal cancer. Ecancermedicalscience 7:357PubMedPubMedCentral
Metadata
Title
Robot-assisted surgery for the radical treatment of deep infiltrating endometriosis with colorectal involvement: short- and mid-term surgical and functional outcomes
Authors
Luca Morelli
Alessandra Perutelli
Matteo Palmeri
Simone Guadagni
Maria Donatella Mariniello
Gregorio Di Franco
Vito Cela
Benedetta Brundu
Maria Giovanna Salerno
Giulio Di Candio
Franco Mosca
Publication date
01-03-2016
Publisher
Springer Berlin Heidelberg
Published in
International Journal of Colorectal Disease / Issue 3/2016
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI
https://doi.org/10.1007/s00384-015-2477-2

Other articles of this Issue 3/2016

International Journal of Colorectal Disease 3/2016 Go to the issue