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International Journal of Colorectal Disease

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01-02-2010 | Original Article

Association between adiponectin, resistin, insulin resistance, and colorectal tumors

Authors: Guzin Gonullu, Hakkı Kahraman, Abdulkerim Bedir, Ahmet Bektas, Idris Yücel

Published in: International Journal of Colorectal Disease | Issue 2/2010

Abstract

Purpose

In this study, we have examined the correlation between colorectal cancer (CRC) and serum adiponectin and resistin levels, body mass index and insulin resistance.

Methods

The relation between serum adiponectin and resistin levels, obesity and insulin resistance in 36 CRC patients and 37 controls was examined.

Results

Insulin and homeostasis model assessment insulin resistance index (HOMA-IR) levels were higher, and adiponectin levels were significantly decreased in patients versus controls, whereas, resistin levels were significantly increased. A negative correlation between adiponectin, HOMA-IR, and insulin and a positive correlation between HOMA-IR, insulin, and stage were detected. There was no correlation between the stage and resistin. Adiponectin level negatively correlated with the stage. Adiponectin and resistin could play a role in colon cancer carcinogenesis, and adiponectin could be responsible for poor prognosis in colorectal cancer.

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Title: Association between adiponectin, resistin, insulin resistance, and colorectal tumors
Authors: Guzin Gonullu
Hakkı Kahraman
Abdulkerim Bedir
Ahmet Bektas
Idris Yücel
Publication date: 01-02-2010
Publisher: Springer-Verlag
Published in: International Journal of Colorectal Disease / Issue 2/2010
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI: https://doi.org/10.1007/s00384-009-0828-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Association between adiponectin, resistin, insulin resistance, and colorectal tumors

Abstract

Purpose

Methods

Results

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

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