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International Journal of Colorectal Disease

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01-07-2009 | Original Article

Survival, surgical management and perioperative mortality of colorectal cancer in the 21-year experience of a specialised registry

Authors: Maurizio Ponz de Leon, Annalisa Pezzi, Piero Benatti, Antonio Manenti, Giuseppina Rossi, Carmela di Gregorio, Luca Roncucci

Published in: International Journal of Colorectal Disease | Issue 7/2009

Abstract

Background and aims

A general improvement of colorectal cancer prognosis has been observed. Reasons of this more favourable trend are diffusion of screening, advancements in molecular biology, new developments in chemotherapy and surgical techniques. Through the data of a colorectal cancer registry, we purposed to evaluate changes in surgical procedures for colorectal neoplasms and to analyse trends of perioperative mortality.

Patients and methods

Patients with colorectal cancer were registered from 1984 to 2004. The main surgical procedures were recorded and classified. Perioperative mortality was defined as death of patients within 1 month since the operation.

Results

Regression analysis showed an increase over time of right and left hemicolectomy. Both colectomy and endoscopic polypectomy showed significant rise over time. In contrast, abdominoperineal operations dropped during the study period. A similar decrease was observed for palliative surgery. Perioperative mortality declined from 7–11% to 3–6% of all operations; main factors associated with perioperative mortality were presence of comorbidities, increasing age and advanced stage.

Conclusion

The better prognosis of patients with colorectal cancer was associated with changes of surgical techniques, with a tendency to prefer large operations over limited resections. Perioperative mortality showed a gradual decrease and is at present in the order of 3% to 6% of all operations.

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Title: Survival, surgical management and perioperative mortality of colorectal cancer in the 21-year experience of a specialised registry
Authors: Maurizio Ponz de Leon
Annalisa Pezzi
Piero Benatti
Antonio Manenti
Giuseppina Rossi
Carmela di Gregorio
Luca Roncucci
Publication date: 01-07-2009
Publisher: Springer-Verlag
Published in: International Journal of Colorectal Disease / Issue 7/2009
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI: https://doi.org/10.1007/s00384-009-0687-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Survival, surgical management and perioperative mortality of colorectal cancer in the 21-year experience of a specialised registry

Abstract

Background and aims

Patients and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background and aims

Patients and methods

Results

Conclusion

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