Skip to main content
Top
Published in: International Journal of Colorectal Disease 3/2008

01-03-2008 | Original Article

Evaluation of selective defunctioning stoma after low anterior resection for rectal cancer

Authors: B. Lefebure, J. J. Tuech, V. Bridoux, B. Costaglioli, M. Scotte, P. Teniere, F. Michot

Published in: International Journal of Colorectal Disease | Issue 3/2008

Login to get access

Abstract

Background

Anastomotic leakage is a major concern after resection for low rectal cancer. Therefore, the use of a defunctioning stoma (DS) has been suggested, but limited data exist to clearly determine the necessity of a routine diversion. In our department, the indication of DS was evaluated subjectively by the operating surgeon. The aim of this study was to evaluate the selective use of fecal diversion.

Materials and methods

Retrospective chart review of patients who underwent low anterior resection for carcinoma was performed. The incidence and consequences of clinical leaks were determined in these patients who were considered in two groups: defunctioning stoma and no defunctioning stoma.

Results

From 1995 to 2005, 132 consecutive patients underwent low anterior resection; a DS was performed in 42 patients (31.8%). Median level of anastomosis was 4 cm in both groups. Overall clinical leakage rate was 9.8%: 7.1% (n = 3) with a DS and 11% (n = 10) without a stoma. Mortality rate was 1.5% (n = 2), both in the unprotected group. No patient in the diversion group required a permanent stoma, contrasting with four unprotected patients in which continuity could not be restored after break down of the anastomosis.

Conclusion

Finding lower clinical leakage rate in a probable higher risk group and better outcome when a leak occurs in our study constituted strong evidence of the effectiveness of a DS. Selective use of a DS based on subjective assessment at the time of surgery could not allow experienced surgeons to perform single-stage procedure safely. Construction of a DS seems useful for patients with distal rectal cancer.
Literature
1.
go back to reference Karanjia ND, Corder AP, Holdsworth PJ, Heald RJ (1991) Risk of peritonitis and fatal septicaemia and the need to defunction the low anastomosis. Br J Surg 78:196–198PubMedCrossRef Karanjia ND, Corder AP, Holdsworth PJ, Heald RJ (1991) Risk of peritonitis and fatal septicaemia and the need to defunction the low anastomosis. Br J Surg 78:196–198PubMedCrossRef
2.
go back to reference Heald RJ, Ryall RD (1986) Recurrence and survival after total mesorectal excision for rectal cancer. Lancet 1:1479–1482PubMedCrossRef Heald RJ, Ryall RD (1986) Recurrence and survival after total mesorectal excision for rectal cancer. Lancet 1:1479–1482PubMedCrossRef
3.
go back to reference Heald RJ, Husband EM, Ryall RD (1982) The mesorectum in rectal cancer surgery–the clue to pelvic recurrence. Br J Surg 69:613–616PubMedCrossRef Heald RJ, Husband EM, Ryall RD (1982) The mesorectum in rectal cancer surgery–the clue to pelvic recurrence. Br J Surg 69:613–616PubMedCrossRef
4.
go back to reference Parc R, Tiret E, Frileux P, Moszkowski E, Loygue J (1986) Resection and colo-anal anastomosis with colonic reservoir for rectal carcinoma. Br J Surg 73:139–141PubMedCrossRef Parc R, Tiret E, Frileux P, Moszkowski E, Loygue J (1986) Resection and colo-anal anastomosis with colonic reservoir for rectal carcinoma. Br J Surg 73:139–141PubMedCrossRef
5.
go back to reference Lazorthes F, Fages P, Chiotasso P, Bugat R (1986) Synchronous abdominotrans-sphincteric resection of low rectal cancer: new technique for direct colo-anal anastomosis. Br J Surg 73:573–575PubMedCrossRef Lazorthes F, Fages P, Chiotasso P, Bugat R (1986) Synchronous abdominotrans-sphincteric resection of low rectal cancer: new technique for direct colo-anal anastomosis. Br J Surg 73:573–575PubMedCrossRef
6.
go back to reference Rullier E, Laurent C, Bretagnol F, Rullier A, Vendrely V, Zerbib F (2005) Sphincter-saving resection for all rectal carcinomas: the end of the 2 cm distal rule. Ann Surg 241:465–469PubMedCrossRef Rullier E, Laurent C, Bretagnol F, Rullier A, Vendrely V, Zerbib F (2005) Sphincter-saving resection for all rectal carcinomas: the end of the 2 cm distal rule. Ann Surg 241:465–469PubMedCrossRef
7.
go back to reference Arbman G, Nilsson E, Hallbook O, Sjodahl R (1996) Local recurrence following total mesorectal excision for rectal cancer. Br J Surg 83:375–379PubMedCrossRef Arbman G, Nilsson E, Hallbook O, Sjodahl R (1996) Local recurrence following total mesorectal excision for rectal cancer. Br J Surg 83:375–379PubMedCrossRef
8.
go back to reference Karanjia ND, Corder AP, Bearn P, Heald RJ (1994) Leakage from stapled low anastomosis after total mesorectal excision for carcinoma of the rectum. Br J Surg 81:1224–1226PubMedCrossRef Karanjia ND, Corder AP, Bearn P, Heald RJ (1994) Leakage from stapled low anastomosis after total mesorectal excision for carcinoma of the rectum. Br J Surg 81:1224–1226PubMedCrossRef
9.
go back to reference Hilsabeck JR (1982) The presacral space as a collector of fluid accumulations following rectal anastomosis: tolerance of rectal anastomosis to closed suction pelvic drainage. Dis Colon Rectum 25:680–684PubMedCrossRef Hilsabeck JR (1982) The presacral space as a collector of fluid accumulations following rectal anastomosis: tolerance of rectal anastomosis to closed suction pelvic drainage. Dis Colon Rectum 25:680–684PubMedCrossRef
10.
go back to reference Merad F, Hay JM, Fingerhut A, Yahchouchi E, Laborde Y, Pelissier E, Msika S, Flamant Y (1999) Is prophylactic pelvic drainage useful after elective rectal or anal anastomosis? A multicenter controlled randomized trial. French Association for Surgical Research. Surgery 125:529–535PubMed Merad F, Hay JM, Fingerhut A, Yahchouchi E, Laborde Y, Pelissier E, Msika S, Flamant Y (1999) Is prophylactic pelvic drainage useful after elective rectal or anal anastomosis? A multicenter controlled randomized trial. French Association for Surgical Research. Surgery 125:529–535PubMed
11.
go back to reference Fingerhut A, Msika S, Yahchouchi E, Merad F, Hay JM, Millat B (2000) Neither pelvic nor abdominal drainage is needed after anastomosis in elective, uncomplicated, colorectal surgery. Ann Surg 231:613–614PubMedCrossRef Fingerhut A, Msika S, Yahchouchi E, Merad F, Hay JM, Millat B (2000) Neither pelvic nor abdominal drainage is needed after anastomosis in elective, uncomplicated, colorectal surgery. Ann Surg 231:613–614PubMedCrossRef
12.
go back to reference Johnson CD, Lamont PM, Orr N, Lennox M (1989) Is a drain necessary after colonic anastomosis. J R Soc Med 82:661–664PubMed Johnson CD, Lamont PM, Orr N, Lennox M (1989) Is a drain necessary after colonic anastomosis. J R Soc Med 82:661–664PubMed
13.
go back to reference Sagar PM, Couse N, Kerin M, May J, MacFie J (1993) Randomized trial of drainage of colorectal anastomosis. Br J Surg 80:769–771PubMedCrossRef Sagar PM, Couse N, Kerin M, May J, MacFie J (1993) Randomized trial of drainage of colorectal anastomosis. Br J Surg 80:769–771PubMedCrossRef
14.
go back to reference McArdle CS, Hole D (1991) Impact of variability among surgeons on postoperative morbidity and mortality and ultimate survival. BMJ 302:1501–1505PubMed McArdle CS, Hole D (1991) Impact of variability among surgeons on postoperative morbidity and mortality and ultimate survival. BMJ 302:1501–1505PubMed
15.
go back to reference Kessler H, Hermanek P, Wiebelt H (1993) Operative mortality in carcinoma of the rectum. Results of the German Multicentre Study. Int J Colorectal Dis 8:158–166PubMedCrossRef Kessler H, Hermanek P, Wiebelt H (1993) Operative mortality in carcinoma of the rectum. Results of the German Multicentre Study. Int J Colorectal Dis 8:158–166PubMedCrossRef
16.
go back to reference Fielding LP, Stewart-Brown S, Blesovsky L, Kearney G (1980) Anastomotic integrity after operations for large-bowel cancer: a multicentre study. BMJ 281:411–414PubMedCrossRef Fielding LP, Stewart-Brown S, Blesovsky L, Kearney G (1980) Anastomotic integrity after operations for large-bowel cancer: a multicentre study. BMJ 281:411–414PubMedCrossRef
17.
go back to reference Hannan EL, O'Donnell JF, Kilburn H, Bernard HR, Yazici A (1989) Investigation of the relationship between volume and mortality for surgical procedures performed in New York State hospitals. JAMA 262:503–510PubMedCrossRef Hannan EL, O'Donnell JF, Kilburn H, Bernard HR, Yazici A (1989) Investigation of the relationship between volume and mortality for surgical procedures performed in New York State hospitals. JAMA 262:503–510PubMedCrossRef
18.
go back to reference Rullier E, Laurent C, Garrelon JL, Michel P, Saric J, Parneix M (1998) Risk factors for anastomotic leakage after resection of rectal cancer. Br J Surg 85:355–358PubMedCrossRef Rullier E, Laurent C, Garrelon JL, Michel P, Saric J, Parneix M (1998) Risk factors for anastomotic leakage after resection of rectal cancer. Br J Surg 85:355–358PubMedCrossRef
19.
go back to reference Sorensen LT, Jorgensen T, Kirkeby LT, Skovdal J, Vennits B, Wille-Jorgensen P (1999) Smoking and alcohol abuse are major risk factors for anastomotic leakage in colorectal surgery. Br J Surg 86:927–931PubMedCrossRef Sorensen LT, Jorgensen T, Kirkeby LT, Skovdal J, Vennits B, Wille-Jorgensen P (1999) Smoking and alcohol abuse are major risk factors for anastomotic leakage in colorectal surgery. Br J Surg 86:927–931PubMedCrossRef
20.
go back to reference Testini M, Margani M, Amuruso M, Lirridini G, Bonamo GM (2000) The dehiscence of colorectal anastomoses: the risk factors. Ann Ital Chir 71:433–440PubMed Testini M, Margani M, Amuruso M, Lirridini G, Bonamo GM (2000) The dehiscence of colorectal anastomoses: the risk factors. Ann Ital Chir 71:433–440PubMed
21.
go back to reference Parc Y, Frileux P, Schmitt G, Dehni N, Ollivier JM, Parc R (2000) Management of postoperative peritonitis after anterior resection: experience from a referral intensive care unit. Dis Colon Rectum 43:579–587PubMedCrossRef Parc Y, Frileux P, Schmitt G, Dehni N, Ollivier JM, Parc R (2000) Management of postoperative peritonitis after anterior resection: experience from a referral intensive care unit. Dis Colon Rectum 43:579–587PubMedCrossRef
22.
go back to reference Hallbook O, Sjodahl R (1996) Anastomotic leakage and functional outcome after anterior resection of the rectum. Br J Surg 83:60–62PubMedCrossRef Hallbook O, Sjodahl R (1996) Anastomotic leakage and functional outcome after anterior resection of the rectum. Br J Surg 83:60–62PubMedCrossRef
23.
go back to reference Bell SW, Walker KG, Rickard MJ, Sinclair G, Dent OF, Chapuis PH, Bokey EL (2003) Anastomotic leakage after curative anterior resection results in a higher prevalence of local recurrence. Br J Surg 90:1261–1266PubMedCrossRef Bell SW, Walker KG, Rickard MJ, Sinclair G, Dent OF, Chapuis PH, Bokey EL (2003) Anastomotic leakage after curative anterior resection results in a higher prevalence of local recurrence. Br J Surg 90:1261–1266PubMedCrossRef
24.
go back to reference Tornqvist A, Blomquist P, Jiborn H, Zederfeldt B (1990) The effect of diverting colostomy on anastomotic healing after resection of left colon obstruction. An experimental study in the rat. Int J Colorectal Dis 5:167–169PubMedCrossRef Tornqvist A, Blomquist P, Jiborn H, Zederfeldt B (1990) The effect of diverting colostomy on anastomotic healing after resection of left colon obstruction. An experimental study in the rat. Int J Colorectal Dis 5:167–169PubMedCrossRef
25.
go back to reference Mansson P, Fork T, Blomqvist P, Jeppsson B, Thorlacius H (2000) Diverting colostomy increases anastomotic leakage in the rat colon. Eur Surg Res 32:246–250PubMedCrossRef Mansson P, Fork T, Blomqvist P, Jeppsson B, Thorlacius H (2000) Diverting colostomy increases anastomotic leakage in the rat colon. Eur Surg Res 32:246–250PubMedCrossRef
26.
go back to reference Bielecki K, Grotowski M, Kalczak M (1995) Influence of proximal end diverting colostomy on the healing of left-sided colonic anastomosis: an experimental study in rats. Int J Colorectal Dis 10:193–196PubMedCrossRef Bielecki K, Grotowski M, Kalczak M (1995) Influence of proximal end diverting colostomy on the healing of left-sided colonic anastomosis: an experimental study in rats. Int J Colorectal Dis 10:193–196PubMedCrossRef
27.
go back to reference Pakkastie TE, Ovaska JT, Pekkala ES, Luukkonen PE, Jarvinen HJ (1997) A randomized study of colostomies in low colorectal anastomoses. Eur J Surg 163:929–933PubMed Pakkastie TE, Ovaska JT, Pekkala ES, Luukkonen PE, Jarvinen HJ (1997) A randomized study of colostomies in low colorectal anastomoses. Eur J Surg 163:929–933PubMed
28.
go back to reference Dehni N, Schlegel RD, Cunningham C, Guiguet M, Tiret E, Parc R (1998) Influence of a defunctioning stoma on leakage rates after low colorectal anastomosis and colonic J pouch-anal anastomosis. Br J Surg 85:1114–1117PubMedCrossRef Dehni N, Schlegel RD, Cunningham C, Guiguet M, Tiret E, Parc R (1998) Influence of a defunctioning stoma on leakage rates after low colorectal anastomosis and colonic J pouch-anal anastomosis. Br J Surg 85:1114–1117PubMedCrossRef
29.
go back to reference Antonsen HK, Kronborg O (1987) Early complications after low anterior resection for rectal cancer using the EEA stapling device. A prospective trial. Dis Colon Rectum 30:579–583PubMedCrossRef Antonsen HK, Kronborg O (1987) Early complications after low anterior resection for rectal cancer using the EEA stapling device. A prospective trial. Dis Colon Rectum 30:579–583PubMedCrossRef
30.
go back to reference Pakkastie TE, Luukkonen PE, Jarvinen HJ (1994) Anastomotic leakage after anterior resection of the rectum. Eur J Surg 160:293–297PubMed Pakkastie TE, Luukkonen PE, Jarvinen HJ (1994) Anastomotic leakage after anterior resection of the rectum. Eur J Surg 160:293–297PubMed
31.
go back to reference Graffner H, Fredlund P, Olsson SA, Oscarson J, Petersson BG (1983) Protective colostomy in low anterior resection of the rectum using the EEA stapling instrument. A randomized study. Dis Colon Rectum 26:87–90PubMedCrossRef Graffner H, Fredlund P, Olsson SA, Oscarson J, Petersson BG (1983) Protective colostomy in low anterior resection of the rectum using the EEA stapling instrument. A randomized study. Dis Colon Rectum 26:87–90PubMedCrossRef
32.
go back to reference Grabham JA, Moran BJ, Lane RH (1995) Defunctioning colostomy for low anterior resection: a selective approach. Br J Surg 82:1331–1332PubMedCrossRef Grabham JA, Moran BJ, Lane RH (1995) Defunctioning colostomy for low anterior resection: a selective approach. Br J Surg 82:1331–1332PubMedCrossRef
33.
go back to reference Cavaliere F, Pemberton JH, Cosimelli M, Fazio VW, Beart RW (1995) Coloanal anastomosis for rectal cancer. Long-term results at the Mayo and Cleveland Clinics. Dis Colon Rectum 38:807–812PubMedCrossRef Cavaliere F, Pemberton JH, Cosimelli M, Fazio VW, Beart RW (1995) Coloanal anastomosis for rectal cancer. Long-term results at the Mayo and Cleveland Clinics. Dis Colon Rectum 38:807–812PubMedCrossRef
34.
go back to reference Kim NK, Lim DJ, Yun SH, Sohn SK, Min JS (2001) Ultralow anterior resection and coloanal anastomosis for distal rectal cancer: functional and oncological results. Int J colorectal Dis 16:234–237PubMedCrossRef Kim NK, Lim DJ, Yun SH, Sohn SK, Min JS (2001) Ultralow anterior resection and coloanal anastomosis for distal rectal cancer: functional and oncological results. Int J colorectal Dis 16:234–237PubMedCrossRef
35.
go back to reference Fielding LP, Stewart-Brown S, Hittinger R, Blesovsky L (1984) Covering stoma for elective anterior resection of the rectum: an outmoded operation. Am J Surg 147:524–530PubMedCrossRef Fielding LP, Stewart-Brown S, Hittinger R, Blesovsky L (1984) Covering stoma for elective anterior resection of the rectum: an outmoded operation. Am J Surg 147:524–530PubMedCrossRef
36.
go back to reference Mealy K, Burke P, Hyland J (1992) Anterior resection without a defunctioning colostomy: questions of safety. Br J Surg 79:305–307PubMedCrossRef Mealy K, Burke P, Hyland J (1992) Anterior resection without a defunctioning colostomy: questions of safety. Br J Surg 79:305–307PubMedCrossRef
37.
go back to reference Peeters KC, Tollenaar RA, Marijnen CA, Klein Kranenbarg E, Steup WH, Wiggers T, Rutten HJ, van de Velde CJ (2005) Risk factors for anastomotic failure after total mesorectal excision of rectal cancer. Br J Surg 92:211–216PubMedCrossRef Peeters KC, Tollenaar RA, Marijnen CA, Klein Kranenbarg E, Steup WH, Wiggers T, Rutten HJ, van de Velde CJ (2005) Risk factors for anastomotic failure after total mesorectal excision of rectal cancer. Br J Surg 92:211–216PubMedCrossRef
38.
39.
go back to reference Frileux P, Quilichini MA, Cugnenc PH, Parc R, Levy E, Loygue J (1985) Postoperative peritonitis of colonic origin. Apropos of 155 cases. Ann Chir 39:649–659PubMed Frileux P, Quilichini MA, Cugnenc PH, Parc R, Levy E, Loygue J (1985) Postoperative peritonitis of colonic origin. Apropos of 155 cases. Ann Chir 39:649–659PubMed
40.
go back to reference Schrock TR, Deveney CW, Dunphy JE (1973) Factor contributing to leakage of colonic anastomoses. Ann Surg 177:513–518PubMedCrossRef Schrock TR, Deveney CW, Dunphy JE (1973) Factor contributing to leakage of colonic anastomoses. Ann Surg 177:513–518PubMedCrossRef
Metadata
Title
Evaluation of selective defunctioning stoma after low anterior resection for rectal cancer
Authors
B. Lefebure
J. J. Tuech
V. Bridoux
B. Costaglioli
M. Scotte
P. Teniere
F. Michot
Publication date
01-03-2008
Publisher
Springer-Verlag
Published in
International Journal of Colorectal Disease / Issue 3/2008
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI
https://doi.org/10.1007/s00384-007-0380-1

Other articles of this Issue 3/2008

International Journal of Colorectal Disease 3/2008 Go to the issue