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Pediatric Surgery International

Published in:

01-06-2014 | Original Article

Gastroschisis-related complications requiring further surgical interventions

Authors: Florian Friedmacher, Andras Hock, Christoph Castellani, Alexander Avian, Michael E. Höllwarth

Published in: Pediatric Surgery International | Issue 6/2014

Abstract

Purpose

The aim of this study was to determine the incidence of gastroschisis-related complications (GRCs) after closure of the abdominal wall defect, with a focus on frequency, type and timing of required surgical interventions, and to identify the impact of these on further outcome.

Methods

All gastroschisis patients treated from 1975 to 2008 in a tertiary-level center were retrospectively reviewed. Surgical procedures for GRCs following abdominal wall closure of simple gastroschisis [SG (intact continuous bowel)] and complex gastroschisis [CG (additional gastrointestinal malformations)] were compared, and outcomes were determined.

Results

One hundred and eight patients were identified with a median follow-up of 15.0 years (range 4–37). Ninety-four (87 %) had SG, and 14 (13 %) CG. Surgical interventions for GRCs were performed in 28 (26 %) patients with 16 requiring multiple operations. Overall, 60 surgical procedures were performed. Bowel obstruction (n = 34) was the most common GRC, followed by anastomotic stricture (n = 8) and ischemic bowel (n = 3). The median interval between gastroschisis closure and secondary surgery for GRCs was 62.5 days (range 1 day–15 years). Surgical interventions were significantly more frequent in CG compared with SG [12/14 (86 %) vs. 16/94 (17 %); P < 0.0001]. The overall survival rate was 90 %. Significantly, more patients required parenteral nutrition for more than 28 days [9/28 (32 %) vs. 13/80 (16 %); P = 0.0468], longer median time to achieve full enteral feedings (87 vs. 33 days; P < 0.0001) and longer median hospital stay (117 vs. 54 days; P < 0.0001) compared with those not requiring additional surgery.

Conclusion

GRCs requiring surgical interventions were more common in patients with CG, which were associated with delay in achieving full enteral feedings and prolonged hospital stay.

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Title: Gastroschisis-related complications requiring further surgical interventions
Authors: Florian Friedmacher
Andras Hock
Christoph Castellani
Alexander Avian
Michael E. Höllwarth
Publication date: 01-06-2014
Publisher: Springer Berlin Heidelberg
Published in: Pediatric Surgery International / Issue 6/2014
Print ISSN: 0179-0358
Electronic ISSN: 1437-9813
DOI: https://doi.org/10.1007/s00383-014-3500-3

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Gastroschisis-related complications requiring further surgical interventions

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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