Top

Published in:

01-12-2005 | Case Report

Antiangiogenic therapy for a large splenic hemangioma

Authors: Saleem Islam, Erika A. Newman, Peter J. Strouse, James D. Geiger

Published in: Pediatric Surgery International | Issue 12/2005

Abstract

Hemangiomas involving the spleen are rare and seldom symptomatic. Treatment options for large lesions usually consist of splenectomy, embolization, or both. Antiangiogenic treatment has not been reported previously as an effective alternative for this type of lesion. We report our experience of successfully using glucocorticoids in an infant with a large hemangioma of the spleen.

Coffin CM, Dehner LP (1993) Vascular tumors in children and adolescents: a clinicopathologic study of 228 tumors in 222 patients. Pathol Annu 28:97–120PubMed

Panuel M, Ternier F, Michael G et al (1992) Splenic hemangioma: Report of 3 pediatric cases with pathologic correlation. Pediatr Radiol 22:213–216CrossRefPubMed

Husni EA (1961) The clinical course of splenic hemangioma with emphasis on spontaneous rupture. Arch Surg 83:681–688PubMed

Wick MR, Scheithaur BW, Smith SL, Beart RW Jr (1982) Primary non-lymphoreticular malignant neoplasms of the spleen. Am J Surg Pathol 6:229–242PubMedCrossRef

Folkman J (2003) Angiogenesis inhibitors: a new class of drugs. Cancer Biol Ther 2(4 Suppl 1):S127–S133PubMed

Sencer S, Coulter-Knoff A, Day D (1987) Splenic hemangioma with thrombocytopenia in a newborn. Pediatrics 79:960–966PubMed

Wilcox TM, Speer RW, Schlinker RT, Sarr MG (2000) Hemangioma of the spleen: presentation, diagnosis and management. J Gastrointest Surg 4:611–613CrossRefPubMed

Pakter RL, Fishman EK, Nussbaum A et al (1987) CT findings in splenic hemangioma in the Klippel--Traenaunay--Weber syndrome. J Comput Assist Tomogr 11:88–91PubMedCrossRef

Herman TE, McAlister PWH, Dehner LP, Skinner M (1997) Beckwith-Wiedemann syndrome and splenic hemangioma. Pediatr Radiol 27:350–352CrossRefPubMed

10.

Castriota-Scanderbeg A, Mingarelli R, Sacco M, Dallapicoln B (1997) Splenic hemangioma in Turner syndrome --- a case report. Pediatr Radiol 27:894PubMed

11.

Chang E, Boyd A, Nelson CC et al (1997) Successful treatment of infantile hemangiomas with interferon-alpha-2b. J Pediatr Hematol Oncol 19:237–244CrossRefPubMed

12.

Rice HE (2005) Pediatric spleen surgery. In: Oldham KT, Colombani PM, Foglia RP, Skinner MA (eds) Principles and practice of pediatric surgery. Lippincott William and Wilkins, Philadelphia, pp 1511–1522

13.

Paterson A, Frush DP, Donnelly LF et al (1999) A pattern-oriented approach to splenic imaging in infants and children. Radiographics 19:1465–1485PubMed

14.

Ferrozzi F, Bova D, Draghi F, Garlaschi G (1996) CT findings in primary vascular tumors of the spleen. AJR 166:1097–1101PubMed

15.

Rose SC, Kumpe DA, Manco-Johnson ML (1986) Radiographic appearance of diffuse splenic hemangiomatosis. Gastrointest Radiol 11:342–345CrossRefPubMed

16.

Yano H, Imasato M, Monden T, Okamoto S (2003) Hand-assisted laparoscopic splenectomy for splenic vascular tumors: report of two cases. Surg Laparosc Endosc Percutan Tech 13:286–289CrossRefPubMed

Title: Antiangiogenic therapy for a large splenic hemangioma
Authors: Saleem Islam
Erika A. Newman
Peter J. Strouse
James D. Geiger
Publication date: 01-12-2005
Publisher: Springer-Verlag
Published in: Pediatric Surgery International / Issue 12/2005
Print ISSN: 0179-0358
Electronic ISSN: 1437-9813
DOI: https://doi.org/10.1007/s00383-005-1533-3

2024 ASCO Annual Meeting

Springer Medicine

Antiangiogenic therapy for a large splenic hemangioma

Abstract

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 12/2005

Delayed gastric emptying and malrotation in gastroesophageal reflux disease

Late-onset hemothorax after the Nuss procedure for funnel chest

Laparoscopic percutaneous extraperitoneal closure (LPEC) method for the exploration and treatment of inguinal hernia in girls

The midterm success rates of tubularized incised plate urethroplasty in reoperative patients with distal or midpenile hypospadias

An extremely rare case of symptomatic right hepatic duct diverticulum located outside the liver

Efficacy of OK-432 local injection for the treatment of a neonatal branchial cleft cyst: a case report