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Published in: Child's Nervous System 7/2023

07-01-2023 | Prenatal Care | Original Article

Influence of social, demographic, and clinical factors in live births with spinal dysraphism in Brazil: an ecological study of 21 years

Authors: Raissa Tereza Casseb Oliveira, Diego Bessa Dantas, Edila Monteiro de Andrade, Márcio Vinicius de Gouveia Affonso, Ana Beatriz Rocha de Marin, Fabiana de Campos Gomes, Nelson Veiga Gonçalves, João Simão de Melo-Neto

Published in: Child's Nervous System | Issue 7/2023

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Abstract

Objectives

This study aimed to verify possible associations between sociodemographic and clinical factors in live births with spinal dysraphism.

Methods

An analytical (descriptive and inferential) and ecological study was carried out based on secondary data of 11,308 live births with spinal dysraphism registered in the Live Birth Information System (SINASC) in Brazil from 1999 to 2019. Demographic factors analyzed were age, education, mothers’ marital status and geographic region. The clinical factors analyzed were duration, gestation period, birthweight, and number of prenatal visits performed by women who underwent medical follow-up.

Results

There was an increase in the number of cases of spinal dysraphism in recent years in Brazil with an annual percentage variation of 3.52%. However, the period from 2005 to 2009 showed a reduction in live births with spinal dysraphism. The regions with the highest incidence were the South and Southeast. The risk increased in mothers born after 1980, older than 30 years and with a high level of education. The risk was increased in live births of whites and blacks, born from double pregnancy and with body weight less than 3000 g. The absence of prenatal care was associated with a higher incidence.

Conclusion

Sociodemographic and clinical factors have specific characteristics that can predict spinal dysraphism in newborns in Brazil.
Literature
6.
go back to reference Hunter GW (1993) Brain and spinal cord. In: Human malformations and related anomalies. Editors: Stevenson ER, Hall JG, Goodman RM. New York: Oxford University Press, pp. 109–31 Hunter GW (1993) Brain and spinal cord. In: Human malformations and related anomalies. Editors: Stevenson ER, Hall JG, Goodman RM. New York: Oxford University Press, pp. 109–31
9.
go back to reference Shaw GM, Carmichael SL, Kaidarova Z, Harris JA (2003) Differential risks to males and females for congenital malformations among 2.5 million California births, 1989–1997. Birth Defects Res A Clin Mol Teratol 67:953–8 Shaw GM, Carmichael SL, Kaidarova Z, Harris JA (2003) Differential risks to males and females for congenital malformations among 2.5 million California births, 1989–1997. Birth Defects Res A Clin Mol Teratol 67:953–8
13.
go back to reference Rosenberg PS, Check DP, Anderson WF (2014) A web tool for age-period-cohort analysis of cancer incidence and mortality rates. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 23(11):2296–2302. https://doi.org/10.1158/1055-9965.EPI-14-0300CrossRef Rosenberg PS, Check DP, Anderson WF (2014) A web tool for age-period-cohort analysis of cancer incidence and mortality rates. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 23(11):2296–2302. https://​doi.​org/​10.​1158/​1055-9965.​EPI-14-0300CrossRef
15.
go back to reference Ministry of Health (2013) National Program for Iron Supplementation: manual of general conduct. Brasília: Editora MS, pp. 24 Ministry of Health (2013) National Program for Iron Supplementation: manual of general conduct. Brasília: Editora MS, pp. 24
Metadata
Title
Influence of social, demographic, and clinical factors in live births with spinal dysraphism in Brazil: an ecological study of 21 years
Authors
Raissa Tereza Casseb Oliveira
Diego Bessa Dantas
Edila Monteiro de Andrade
Márcio Vinicius de Gouveia Affonso
Ana Beatriz Rocha de Marin
Fabiana de Campos Gomes
Nelson Veiga Gonçalves
João Simão de Melo-Neto
Publication date
07-01-2023
Publisher
Springer Berlin Heidelberg
Published in
Child's Nervous System / Issue 7/2023
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-022-05779-y

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