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Published in: Child's Nervous System 12/2010

01-12-2010 | Case Report

A peri-trigonal giant tumefactive cavernous malformation: case report and review of literature

Authors: Sumit Thakar, Sunil V. Furtado, Nandita Ghosal, A. S. Hegde

Published in: Child's Nervous System | Issue 12/2010

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Abstract

Introduction

Giant cavernous malformations (GCMs) constitute an uncommon entity in the diagnostic armamentarium of the neurosurgeon. We report a 3-year-old boy with a GCM in the peri-trigonal region and review 13 other paediatric cases previously reported in literature.

Case

A 3-year-old boy presented with right-sided hemiparesis and features of raised intracranial pressure of short duration. Computed tomography showed a large left peri-trigonal mass with a bleed. Magnetic resonance imaging showed associated perilesional edema and mass effect, rendering the lesion a tumefactive appearance. He underwent total excision of the lesion, with subsequent recovery of hemiparesis. Histopathology was reported as a cavernoma.

Discussion

The clinico-radiological presentation of GCM is discussed based on a case report and relevant cases in literature. Good surgical outcome can be expected with total microsurgical excision.

Conclusion

A giant cavernous malformation should be one of the differentials of a lesion with a tumefactive clinico-radiological presentation in children. There should be a high index of suspicion for such a diagnosis, especially when the lesion does not enhance with contrast. This is the third case report in paediatric literature describing a periventricular location of this unusual lesion.
Literature
1.
go back to reference Chicani CF, Miller NR, Tamargo RJ (2003) Giant cavernous malformation of the occipital lobe. J Neuroophthalmol 23:151–153PubMed Chicani CF, Miller NR, Tamargo RJ (2003) Giant cavernous malformation of the occipital lobe. J Neuroophthalmol 23:151–153PubMed
2.
go back to reference de Andrade GC, Prandini MN, Braga FM (2002) Giant cavernous angioma: report of two cases. Arq Neuropsiquiatr 60:481–486PubMed de Andrade GC, Prandini MN, Braga FM (2002) Giant cavernous angioma: report of two cases. Arq Neuropsiquiatr 60:481–486PubMed
3.
go back to reference Hayashi T, Fukui M, Shoyima K, Utsonomiya H, Kawasaki K (1985) Giant cerebellar hemangioma in an infant. Childs Nerv Syst 1:230–233CrossRefPubMed Hayashi T, Fukui M, Shoyima K, Utsonomiya H, Kawasaki K (1985) Giant cerebellar hemangioma in an infant. Childs Nerv Syst 1:230–233CrossRefPubMed
5.
go back to reference Hyodo A, Yanaka K, Higuchi O, Tomono Y, Nose T (2000) Giant interdural cavernous hemangioma at the convexity. Case illustration. J Neurosurg 92:503CrossRefPubMed Hyodo A, Yanaka K, Higuchi O, Tomono Y, Nose T (2000) Giant interdural cavernous hemangioma at the convexity. Case illustration. J Neurosurg 92:503CrossRefPubMed
6.
go back to reference Kan P, Tubay M, Osborn A, Blaser S, Couldwell WT (2008) Radiographic features of tumefactive giant cavernous angiomas. Acta Neurochir (Wien) 150:49–55CrossRef Kan P, Tubay M, Osborn A, Blaser S, Couldwell WT (2008) Radiographic features of tumefactive giant cavernous angiomas. Acta Neurochir (Wien) 150:49–55CrossRef
7.
go back to reference Kawagishi J, Suzuki M, Kayama T, Yoshimoto T (1993) Huge multilobular cavernous angioma in an infant: case report. Neurosurgery 32:1028–1031CrossRefPubMed Kawagishi J, Suzuki M, Kayama T, Yoshimoto T (1993) Huge multilobular cavernous angioma in an infant: case report. Neurosurgery 32:1028–1031CrossRefPubMed
8.
go back to reference Khosla VK, Banerjee AK, Mathuriya SN, Mehta S (1984) Giant cystic cavernoma in a child. Case report. J Neurosurg 60:1297–1299CrossRefPubMed Khosla VK, Banerjee AK, Mathuriya SN, Mehta S (1984) Giant cystic cavernoma in a child. Case report. J Neurosurg 60:1297–1299CrossRefPubMed
9.
go back to reference Kim EY, Song JH, Kim MH, Park HK, Kim SH, Shin KM et al (1997) Cavernous angioma associated with developmental venous anomaly. J Korean Neurosurg Soc 26:1371–1378 Kim EY, Song JH, Kim MH, Park HK, Kim SH, Shin KM et al (1997) Cavernous angioma associated with developmental venous anomaly. J Korean Neurosurg Soc 26:1371–1378
10.
go back to reference Kim YJ, Kim JE, Kim NR, Kim HS (2007) Imaging findings of giant cavernous malformation with a focal infiltrative pattern. Pediatr Radiol 37:1039–1042CrossRefPubMed Kim YJ, Kim JE, Kim NR, Kim HS (2007) Imaging findings of giant cavernous malformation with a focal infiltrative pattern. Pediatr Radiol 37:1039–1042CrossRefPubMed
11.
go back to reference Lawton MT, Vates GE, Quinones-Hinojosa A, Mcdonald W, Marchuk D (2004) Giant infiltrative cavernous malformation: clinical presentation, intervention, and genetic analysis: case report. Neurosurgery 55:988–995CrossRef Lawton MT, Vates GE, Quinones-Hinojosa A, Mcdonald W, Marchuk D (2004) Giant infiltrative cavernous malformation: clinical presentation, intervention, and genetic analysis: case report. Neurosurgery 55:988–995CrossRef
12.
go back to reference Maraire JN, Awad IA (1995) Intracranial cavernous malformations: lesion behaviour and management strategies. Neurosurgery 37:591–605CrossRefPubMed Maraire JN, Awad IA (1995) Intracranial cavernous malformations: lesion behaviour and management strategies. Neurosurgery 37:591–605CrossRefPubMed
13.
go back to reference Martinez-Lage JF, de la Fuente I, de San R, Pedro J, Fuster JL, Espejo MAP, Herrero MT (2008) Cavernomas in children with brain tumors: a late complication of radiotherapy. Neurocirugía 19:50–54PubMed Martinez-Lage JF, de la Fuente I, de San R, Pedro J, Fuster JL, Espejo MAP, Herrero MT (2008) Cavernomas in children with brain tumors: a late complication of radiotherapy. Neurocirugía 19:50–54PubMed
14.
go back to reference Penfield W, Ward A (1948) Calcifying epileptogenic lesions. Haemangioma calcificans. Report of a case. Arch Neurol Psychiatry 60:20–36PubMed Penfield W, Ward A (1948) Calcifying epileptogenic lesions. Haemangioma calcificans. Report of a case. Arch Neurol Psychiatry 60:20–36PubMed
15.
go back to reference Son DW, Lee SW, Choi CH (2008) Giant cavernous malformation: a case report and review of the literature. J Korean Neurosurg Soc 43:198–200CrossRefPubMed Son DW, Lee SW, Choi CH (2008) Giant cavernous malformation: a case report and review of the literature. J Korean Neurosurg Soc 43:198–200CrossRefPubMed
16.
go back to reference Sure U, Butz N, Schlegel J, Siegel AM, Wakat JP, Mennel HD et al (2001) Endothelial proliferation, neoangiogenesis, and potential de novo generation of cerebrovascular malformations. J Neurosurg 94:972–977CrossRefPubMed Sure U, Butz N, Schlegel J, Siegel AM, Wakat JP, Mennel HD et al (2001) Endothelial proliferation, neoangiogenesis, and potential de novo generation of cerebrovascular malformations. J Neurosurg 94:972–977CrossRefPubMed
17.
go back to reference Thiex R, Kruger R, Friese S, Gronewaller E, Kuker W (2003) Giant cavernoma of the brain stem: value of delayed MR imaging after contrast injection. Eur Radiol 13(Suppl 6):L219–25CrossRef Thiex R, Kruger R, Friese S, Gronewaller E, Kuker W (2003) Giant cavernoma of the brain stem: value of delayed MR imaging after contrast injection. Eur Radiol 13(Suppl 6):L219–25CrossRef
18.
go back to reference Van Lindert EJ, Tan TC, Grotenhuis JA, Wesseling P (2007) Giant cavernous hemangiomas: report of three cases. Neurosurg Rev 30:83–92CrossRefPubMed Van Lindert EJ, Tan TC, Grotenhuis JA, Wesseling P (2007) Giant cavernous hemangiomas: report of three cases. Neurosurg Rev 30:83–92CrossRefPubMed
19.
go back to reference Voelker JL, Stewart DH, Schochet SS Jr (1998) Giant intracranial and extracranial cavernous malformation. Case report. J Neurosurg 89:465–469CrossRefPubMed Voelker JL, Stewart DH, Schochet SS Jr (1998) Giant intracranial and extracranial cavernous malformation. Case report. J Neurosurg 89:465–469CrossRefPubMed
Metadata
Title
A peri-trigonal giant tumefactive cavernous malformation: case report and review of literature
Authors
Sumit Thakar
Sunil V. Furtado
Nandita Ghosal
A. S. Hegde
Publication date
01-12-2010
Publisher
Springer-Verlag
Published in
Child's Nervous System / Issue 12/2010
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-010-1237-4

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