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Child's Nervous System
Published in: Child's Nervous System 11/2008

01-11-2008 | Original Paper

Endoscopic biopsy during third ventriculostomy in paediatric pineal region tumours

Authors: Yahia Z. Al-Tamimi, Deepti Bhargava, Surash Surash, Roberto E. Ramirez, Federica Novegno, Darach W. Crimmins, Atul K. Tyagi, Paul D. Chumas

Published in: Child's Nervous System | Issue 11/2008

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Abstract

Objects

The goal of the study was to establish if endoscopic biopsy during third ventriculostomy contributes to morbidity in the management of paediatric pineal region tumours presenting with hydrocephalus.

Materials and methods

This study was a retrospective descriptive study in patients less than 18 years of age who have presented with a pineal region tumour between 2000 and 2006. Data were obtained from case notes. Twelve patients had presented with a pineal region mass with symptomatic hydrocephalus. Of these, eight had endoscopic biopsy during third ventriculostomy.

Conclusions

No mortality or permanent morbidity was seen following endoscopic biopsy. Two cases of transient worsening of pre-operative diplopia were noted. Diagnostic sensitivity for endoscopic biopsy is 75%. Tumour markers were not significantly raised in any plasma and cerebrospinal fluid samples. Endoscopic biopsy during third ventriculostomy in paediatric pineal region tumours is safe and results in good diagnostic yields. It should play an integral role in the initial management of patients in this setting.
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Metadata
Title
Endoscopic biopsy during third ventriculostomy in paediatric pineal region tumours
Authors
Yahia Z. Al-Tamimi
Deepti Bhargava
Surash Surash
Roberto E. Ramirez
Federica Novegno
Darach W. Crimmins
Atul K. Tyagi
Paul D. Chumas
Publication date
01-11-2008
Publisher
Springer-Verlag
Published in
Child's Nervous System / Issue 11/2008
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-008-0632-6

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