Published in:
01-11-2015 | Case Report
Cardiac tamponade leading to the diagnosis of eosinophilic granulomatosis with polyangiitis (Churg−Strauss syndrome): a case report and review of the literature
Authors:
Toshiyuki Yano, Shutaro Ishimura, Tetsuaki Furukawa, Masayuki Koyama, Marenao Tanaka, Shinya Shimoshige, Akiyoshi Hashimoto, Tetsuji Miura
Published in:
Heart and Vessels
|
Issue 6/2015
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Abstract
Eosinophilic granulomatosis with polyangiitis (EGPA), which was previously called Churg−Strauss syndrome, is a necrotizing systemic vasculitis of unknown cause accompanied by prominent eosinophilia. Cardiovascular complications, including eosinophilic myocarditis, are a major cause of mortality in this disorder. Acute pericarditis with slight pericardial effusion is a typical manifestation in EGPA, though hemodynamically significant pericardial effusion has been reported in a few cases. We report a case that initially presented with isolated cardiac tamponade, which was followed by systemic manifestations of EGPA over 3 weeks. Including the present case, previous EGPA cases with cardiac tamponade are reviewed to delineate its clinical characteristics.