Skip to main content
Top
Published in: Heart and Vessels 6/2010

01-11-2010 | Original Article

Heart valve surgery in octogenarians: operative and long-term results

Authors: Shigeaki Aoyagi, Shuji Fukunaga, Koichi Arinaga, Hiroshi Tomoeda, Koji Akasu, Tomohiro Ueda

Published in: Heart and Vessels | Issue 6/2010

Login to get access

Abstract

This study was performed to evaluate surgical outcomes in octogenarian patients undergoing valve surgery. Sixty patients (mean age 82.3 ± 1.9 years) who underwent valve surgery were reviewed. Aortic valve disease was found in 65% of the patients. Preoperatively, 20% of the patients were in NYHA class IV. An urgent operation and concomitant coronary artery bypass grafting were performed in ten patients each. A bioprosthetic valve was exclusively used for valve replacement except in two patients. Mitral valve repair was done in seven patients. Operative mortality was 13.3% for the period. No risk factors for operative mortality were detected by multivariate analysis; however, urgent operation, preoperative NYHA class IV, preoperative renal dysfunction, perioperative use of an intra-aortic balloon pumping, and prolonged cardiopulmonary bypass time had significant effects on operative mortality. The actuarial survival rate at 1 and 3 years after surgery was 82.6 and 71.5%, respectively, and 97.6% of late survivors reported that their activity level was equal to or better than the preoperative level. Valve surgery can be performed in octogenarian patients with acceptable mortality, good long-term results, and good quality of life. Early referral to surgery should be important to obtain a better postoperative outcome.
Literature
1.
go back to reference Chappini B, Camurri N, Loforte A, Di Marco L, di Bartolomeo R, Marinell G (2004) Outcome after aortic valve replacement in octogenarians. Ann Thorac Surg 78:85–89CrossRef Chappini B, Camurri N, Loforte A, Di Marco L, di Bartolomeo R, Marinell G (2004) Outcome after aortic valve replacement in octogenarians. Ann Thorac Surg 78:85–89CrossRef
2.
go back to reference Nagendran J, Norris C, Maitland A, Koshal A, Toss DB (2005) Is mitral valve surgery safe in octogenarians? Eur J Cardiothorac Surg 28:83–87CrossRefPubMed Nagendran J, Norris C, Maitland A, Koshal A, Toss DB (2005) Is mitral valve surgery safe in octogenarians? Eur J Cardiothorac Surg 28:83–87CrossRefPubMed
3.
go back to reference Johnson WM, Smith JM, Woods SE, Hendy MP, Hiratsuka LF (2005) Cardiac surgery in octogenarians. Does age alone influence outcomes? Arch Surg 140:1089–1093CrossRefPubMed Johnson WM, Smith JM, Woods SE, Hendy MP, Hiratsuka LF (2005) Cardiac surgery in octogenarians. Does age alone influence outcomes? Arch Surg 140:1089–1093CrossRefPubMed
4.
go back to reference Langanay T, De Latour B, Ligier K, Derieux T, Agnino A, Verhoye J-P, Corbineau H, Chaperon J, Leguerrier A (2004) Surgery for aortic stenosis in octogenarians: influence of coronary disease and other comorbidities on hospital mortality. J Heart Valve Dis 13:545–553PubMed Langanay T, De Latour B, Ligier K, Derieux T, Agnino A, Verhoye J-P, Corbineau H, Chaperon J, Leguerrier A (2004) Surgery for aortic stenosis in octogenarians: influence of coronary disease and other comorbidities on hospital mortality. J Heart Valve Dis 13:545–553PubMed
5.
go back to reference Melby SJ, Zierer A, Kaiser SP, Guthrie TJ, Keune JD, Schuessler RB, Pasque MK, Lawton JS, Moazami N, Moon MR, Damiano RJ (2007) Aortic valve replacement in octogenarians: risk factors for early and late mortality. Ann Thorac Surg 83:1651–1657CrossRefPubMed Melby SJ, Zierer A, Kaiser SP, Guthrie TJ, Keune JD, Schuessler RB, Pasque MK, Lawton JS, Moazami N, Moon MR, Damiano RJ (2007) Aortic valve replacement in octogenarians: risk factors for early and late mortality. Ann Thorac Surg 83:1651–1657CrossRefPubMed
6.
go back to reference Aoyagi S, Oryoji A, Nishi Y, Tanaka K, Kosuga K, Oishi K (1994) Long-term results of valve replacement with the St. Jude Medical valve. J Thorac Cardiovasc Surg 108:1021–1029PubMed Aoyagi S, Oryoji A, Nishi Y, Tanaka K, Kosuga K, Oishi K (1994) Long-term results of valve replacement with the St. Jude Medical valve. J Thorac Cardiovasc Surg 108:1021–1029PubMed
7.
go back to reference Carpentier A (1983) Cardiac valve surgery—the “French correction.”. J Thorac Cardiovasc Surg 86:323–337PubMed Carpentier A (1983) Cardiac valve surgery—the “French correction.”. J Thorac Cardiovasc Surg 86:323–337PubMed
8.
go back to reference Grossi EA, Zakow PK, Sussman M, Galloway AC, Delianides J, Baumann G, Colvin SB (2000) Late results of mitral valve reconstruction in the elderly. Ann Thorac Surg 70:1224–1226CrossRefPubMed Grossi EA, Zakow PK, Sussman M, Galloway AC, Delianides J, Baumann G, Colvin SB (2000) Late results of mitral valve reconstruction in the elderly. Ann Thorac Surg 70:1224–1226CrossRefPubMed
9.
go back to reference Ngaage DL, Cowen ME, Griffin S, Guvendik L, Cale AR (2008) Are initial valve operations in octogenarians still high-risk in the current era? J Heart Valve Dis 17:227–232PubMed Ngaage DL, Cowen ME, Griffin S, Guvendik L, Cale AR (2008) Are initial valve operations in octogenarians still high-risk in the current era? J Heart Valve Dis 17:227–232PubMed
10.
go back to reference DiGregorio V, Zehr KJ, Orszulak TA, Mullany CJ, Daly RC, Dearani JA, Schaff HV (2004) Results of mitral surgery in octogenarians with isolated nonrheumatic mitral regurgitation. Ann Thorac Surg 78:807–814CrossRefPubMed DiGregorio V, Zehr KJ, Orszulak TA, Mullany CJ, Daly RC, Dearani JA, Schaff HV (2004) Results of mitral surgery in octogenarians with isolated nonrheumatic mitral regurgitation. Ann Thorac Surg 78:807–814CrossRefPubMed
11.
go back to reference Kohl P, Kerzmann A, Honore C, Comte L, Limet R (2007) Aortic valve surgery in octogenarians: predictive factors for operative and long-term results. Eur J Cardiothorac Surg 31:600–606CrossRef Kohl P, Kerzmann A, Honore C, Comte L, Limet R (2007) Aortic valve surgery in octogenarians: predictive factors for operative and long-term results. Eur J Cardiothorac Surg 31:600–606CrossRef
12.
go back to reference Naagendran J, Norris C, Maitland A, Koshal A, Ross DB (2005) Is mitral valve surgery safe in octogenarians? Eur J Cardiothorac Surg 28:83–87CrossRef Naagendran J, Norris C, Maitland A, Koshal A, Ross DB (2005) Is mitral valve surgery safe in octogenarians? Eur J Cardiothorac Surg 28:83–87CrossRef
13.
go back to reference Bloomstein LZ, Gielchinsky I, Bernstein AD, Parsonnet V, Saunders C, Karanam R, Graves B (2001) Aortic valve replacement in geriatric patients: determinants of in-hospital mortality. Ann Thorac Surg 71:597–600CrossRefPubMed Bloomstein LZ, Gielchinsky I, Bernstein AD, Parsonnet V, Saunders C, Karanam R, Graves B (2001) Aortic valve replacement in geriatric patients: determinants of in-hospital mortality. Ann Thorac Surg 71:597–600CrossRefPubMed
14.
go back to reference Anselmino M, Biondi-Zoccai G, Moretti C, Sheiban I (2008) Percutaneous coronary intervention on left main coronary artery trifurcation. Heart Vessels 23:279–281CrossRefPubMed Anselmino M, Biondi-Zoccai G, Moretti C, Sheiban I (2008) Percutaneous coronary intervention on left main coronary artery trifurcation. Heart Vessels 23:279–281CrossRefPubMed
15.
go back to reference Ricci M, Macedo FIB, Suarez MR, Brown M, Alba J, Salerno TA (2009) Multiple valve surgery with beating heart technique. Ann Thorac Surg 87:527–531CrossRefPubMed Ricci M, Macedo FIB, Suarez MR, Brown M, Alba J, Salerno TA (2009) Multiple valve surgery with beating heart technique. Ann Thorac Surg 87:527–531CrossRefPubMed
16.
go back to reference Logeais Y, Langanay T, Roussin R, Leguerrier A, Rioux C, Chaperon J, de Place C, Mabo P, Pony JC, Daubert JC, Laurent M, Almange C (1994) Surgery for aortic stenosis in elderly patients. A study of surgical risk and predictive factors. Circulation 90:2891–2898PubMed Logeais Y, Langanay T, Roussin R, Leguerrier A, Rioux C, Chaperon J, de Place C, Mabo P, Pony JC, Daubert JC, Laurent M, Almange C (1994) Surgery for aortic stenosis in elderly patients. A study of surgical risk and predictive factors. Circulation 90:2891–2898PubMed
17.
go back to reference Urso S, Sadaba R, Greco E, Pulitani I, Alvarez L, Juaristi A, Goiti JJ (2007) One hundred aortic valve replacements in octogenarians: outcomes and risk factors for early mortality. J Heart Valve Dis 16:139–144PubMed Urso S, Sadaba R, Greco E, Pulitani I, Alvarez L, Juaristi A, Goiti JJ (2007) One hundred aortic valve replacements in octogenarians: outcomes and risk factors for early mortality. J Heart Valve Dis 16:139–144PubMed
18.
go back to reference Colli A, Verhoye J-P, Heijmen R, Strauch JT, Hyde JAJ, Pagano D, Antunes M, Koertke H, Ohri SK, Bail DHL, Leprince P, Van Straten BHM, Gherli T (2008) Antithrombotic therapy after bioprosthetic aortic valve replacement: ACTION registry survey results. Eur J Cardiothorac Surg 33:531–536CrossRefPubMed Colli A, Verhoye J-P, Heijmen R, Strauch JT, Hyde JAJ, Pagano D, Antunes M, Koertke H, Ohri SK, Bail DHL, Leprince P, Van Straten BHM, Gherli T (2008) Antithrombotic therapy after bioprosthetic aortic valve replacement: ACTION registry survey results. Eur J Cardiothorac Surg 33:531–536CrossRefPubMed
19.
go back to reference Armendi JI, Mestres C-A (2008) Antithrombotic therapy after bioprosthetic aortic valve replacement. Eur J Cardiothorac Surg 33:529–530CrossRef Armendi JI, Mestres C-A (2008) Antithrombotic therapy after bioprosthetic aortic valve replacement. Eur J Cardiothorac Surg 33:529–530CrossRef
20.
go back to reference Gherli T, Colli A, Fragnito C, Nicolini F, Borrello B, Saccani S, D’Amico R, Beghi C (2004) Comparing warfarin with aspirin after biological aortic valve replacement: a prospective study. Circulation 110:496–500CrossRefPubMed Gherli T, Colli A, Fragnito C, Nicolini F, Borrello B, Saccani S, D’Amico R, Beghi C (2004) Comparing warfarin with aspirin after biological aortic valve replacement: a prospective study. Circulation 110:496–500CrossRefPubMed
Metadata
Title
Heart valve surgery in octogenarians: operative and long-term results
Authors
Shigeaki Aoyagi
Shuji Fukunaga
Koichi Arinaga
Hiroshi Tomoeda
Koji Akasu
Tomohiro Ueda
Publication date
01-11-2010
Publisher
Springer Japan
Published in
Heart and Vessels / Issue 6/2010
Print ISSN: 0910-8327
Electronic ISSN: 1615-2573
DOI
https://doi.org/10.1007/s00380-010-0009-0

Other articles of this Issue 6/2010

Heart and Vessels 6/2010 Go to the issue