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World Journal of Urology

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18-05-2023 | Human Papillomavirus | Original Article

HPV-infection status and urinary incontinence: a population-based analysis of the NHANES 2005–2016

Authors: Shuai Xia, Shujie Li, Honglin Li

Published in: World Journal of Urology | Issue 6/2023

Abstract

Purpose

Urinary incontinence is a common condition and reduces the quality of life. The purpose of this study was to assess the association between HPV infection and urinary incontinence among adult women in the USA.

Methods

We examined a cross-sectional study using the National Health and Nutrition Examination Survey database. Women who had valid HPV DNA vaginal swab test results and answered the questionnaire about urinary incontinence were selected from six consecutive survey cycles (2005–2006 to 2015–2016). The association between HPV status and urinary incontinence was analyzed using weighted logistic regression. Models adjusted for potential variables were established.

Results

In total, 8348 females aged between 20 and 59 years old were enrolled in this study. 47.8% of participants had a history of urinary incontinence and 43.9% of women were HPV DNA positive. After adjusting for all confounders, women with HPV infection were less likely to have urinary incontinence (OR = 0.88, 95%CI 0.78–0.98). Low-risk HPV infection correlated with a lower incidence of incontinence (OR = 0.88, 95%CI 0.77–1.00). For women aged below 40 years, low-risk HPV infection negatively correlated with stress incontinence (20–29ys: OR = 0.67, 95%CI 0.49–0.94; 30–39ys: OR = 0.71, 95%CI 0.54–0.93). However, low-risk HPV infection positively correlated with stress incontinence (OR = 1.40, 95%CI 1.01–1.95) for women 50–59 years old.

Conclusion

This study revealed a negative association between HPV infection and urinary incontinence in females. Low-risk HPV correlated with stress urinary incontinence, with the reverse trend for participants of different ages.

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Title: HPV-infection status and urinary incontinence: a population-based analysis of the NHANES 2005–2016
Authors: Shuai Xia
Shujie Li
Honglin Li
Publication date: 18-05-2023
Publisher: Springer Berlin Heidelberg
Keywords: Human Papillomavirus
Stress Incontinence
Urinary Incontinence
Urinary Incontinence
Published in: World Journal of Urology / Issue 6/2023
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI: https://doi.org/10.1007/s00345-023-04425-9

Keynote webinar | Spotlight on medication adherence

Springer Medicine

HPV-infection status and urinary incontinence: a population-based analysis of the NHANES 2005–2016

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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