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Published in: World Journal of Urology 3/2022

01-03-2022 | Nephrectomy | Original Article

Outcomes after 20 years of experience in minimally invasive living-donor nephrectomy

Authors: Mireia Musquera, Lluis Peri, Maurizio D’Anna, Tarek Ajami, Maria José Ribal, Antoni Vilaseca, Ignacio Revuelta, Ricardo Álvarez-Vijande, Ana Palacios, Fritz Diekmann, Conchita Monsalve, Beatriz Tena, Laura Izquierdo, Raul Martos, David Paredes, Joan Beltran, Federico Oppenheimer, Antonio Alcaraz

Published in: World Journal of Urology | Issue 3/2022

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Abstract

Introduction

The transperitoneal laparoscopic approach is considered the gold standard technique for living kidney donation. Other accepted laparoscopic techniques include the retroperitoneal approach, natural orifice transluminal endoscopic surgery (NOTES)-assisted, laparo-endoscopic single-site surgery (LESS), with excellent results in the donor and graft. Many studies have compared these techniques with open ones. Our objective is to describe our experience and results in minimally invasive living-donor nephrectomies (MILDN): laparoscopic, NOTES-assisted, and LESS since their introduction in March 2002.

Materials and methods

We conducted a retrospective observational study of donors undergoing MILDN between March 2002 and March 2020.

Results

A total of 714 MILDNs were performed at our centre. All were completed, except for one, because of recipient death. The conventional laparoscopic approach was used in 541 cases (75.88%), NOTES in 116 (16.9%), LESS in 55 (7.7%), and one mini open (0.14%). Two-thirds of the donors were females (478 cases). The mean donor age was 52.87 years (SD 10.93). Six donors (0.8%) were diagnosed beforehand with a small renal mass, which was removed before transplantation in bench surgery. The right kidney was removed in 17.8% of cases. Warm ischaemia time was higher in the NOTES and LESS groups. We had eight conversions. The global intraoperative and postoperative complication rates were 6.8% and 4.9%, respectively. None of the donors developed renal disease during follow-up (mean 3.68 years). Five-year recipient and graft survival rates were 98.8% and 96.8%, respectively.

Conclusions

MILDN techniques are safe for donors and grafts, with low complication.
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Metadata
Title
Outcomes after 20 years of experience in minimally invasive living-donor nephrectomy
Authors
Mireia Musquera
Lluis Peri
Maurizio D’Anna
Tarek Ajami
Maria José Ribal
Antoni Vilaseca
Ignacio Revuelta
Ricardo Álvarez-Vijande
Ana Palacios
Fritz Diekmann
Conchita Monsalve
Beatriz Tena
Laura Izquierdo
Raul Martos
David Paredes
Joan Beltran
Federico Oppenheimer
Antonio Alcaraz
Publication date
01-03-2022
Publisher
Springer Berlin Heidelberg
Published in
World Journal of Urology / Issue 3/2022
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI
https://doi.org/10.1007/s00345-021-03912-1

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