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Published in: World Journal of Urology 2/2010

01-04-2010 | Topic Paper

Clinical observation on 2 micron laser for non-muscle-invasive bladder tumor treatment: single-center experience

Authors: Chen Zhong, Sanwei Guo, Yueqing Tang, Shujie Xia

Published in: World Journal of Urology | Issue 2/2010

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Abstract

Objectives

To evaluate the efficacy and safety of 2 micron continuous wave laser resection of non-muscle-invasive bladder tumor (NMIBT) compared with holmium laser resection of bladder tumor (HoLRBT) and standard transurethral resection of bladder tumor (TURBT).

Methods

Since April 2006 to August 2007, 97 patients with NMIBT were retrospectively collected in this study. All of them were classified into 3 groups, which were treated with 2 micron continuous wave laser resection, holmium laser resection and TURBT, respectively. The preoperative, intraoperative and postoperative clinical data were recorded and compared using SAS 6.12 statistical software.

Results

There were no differences with the preoperative characteristics among the three groups, except the diameter of the tumors. The maximum diameter of the tumors in 2 micron laser group was larger than the other two groups (P < 0.05). Two micron laser group was associated with less hemoglobin decrease compared with TURBT group (P < 0.05). All of the patients were followed and the recurrence rate of the three groups indicated no statistical significance (P > 0.05).

Conclusions

In conclusion, 2 micron continuous wave laser resection of non-muscle-invasive bladder tumor is a safe and reliable treatment. With the distinguished hemostasis, it is an available optional treatment.
Literature
1.
go back to reference Madeb R, Messing EM (2004) Gender, racial and age differences in bladder cancer incidence and mortality. Urol Oncol 22(2):86–92PubMed Madeb R, Messing EM (2004) Gender, racial and age differences in bladder cancer incidence and mortality. Urol Oncol 22(2):86–92PubMed
2.
go back to reference Underwood W 3rd, Dunn RL, Williams C et al (2006) Gender and geographic influence on the racial disparity in bladder cancer mortality in the US. J Am Coll Surg 202(2):284–290CrossRefPubMed Underwood W 3rd, Dunn RL, Williams C et al (2006) Gender and geographic influence on the racial disparity in bladder cancer mortality in the US. J Am Coll Surg 202(2):284–290CrossRefPubMed
3.
go back to reference No authors listed (2009) StatBite: A look at bladder cancer in the United States. J Natl Cancer Inst 101(22):1533CrossRef No authors listed (2009) StatBite: A look at bladder cancer in the United States. J Natl Cancer Inst 101(22):1533CrossRef
4.
go back to reference Shi B, Zhang K, Zhang J et al (2008) Relationship between patient age and superficial transitional cell carcinoma characteristics. Urology 71(6):1186–1190CrossRefPubMed Shi B, Zhang K, Zhang J et al (2008) Relationship between patient age and superficial transitional cell carcinoma characteristics. Urology 71(6):1186–1190CrossRefPubMed
5.
go back to reference Pietrow PK, Smith JJ (2001) Laser treatment for invasive and noninvasive carcinoma of the bladder. J Endourol 15(4):415–418CrossRefPubMed Pietrow PK, Smith JJ (2001) Laser treatment for invasive and noninvasive carcinoma of the bladder. J Endourol 15(4):415–418CrossRefPubMed
6.
go back to reference Devos D, Creac’h C, Laureau E et al (2000) Thulium laser evoked potentials. Normative values for the arms and legs. Neurophysiol Clin 30(5):313–322CrossRefPubMed Devos D, Creac’h C, Laureau E et al (2000) Thulium laser evoked potentials. Normative values for the arms and legs. Neurophysiol Clin 30(5):313–322CrossRefPubMed
7.
go back to reference Fried NM, Murray KE (2005) High-Power thulium fiber laser ablation of urinary tissues at 1.94um. J Endourol 19(1):25–31CrossRefPubMed Fried NM, Murray KE (2005) High-Power thulium fiber laser ablation of urinary tissues at 1.94um. J Endourol 19(1):25–31CrossRefPubMed
8.
go back to reference Xia SJ, Zhuo J, Sun XW et al (2008) Thulium laser versus standard transurethral resection of the prostate: a randomized prospective trial. Eur Urol 53(2):382–389CrossRefPubMed Xia SJ, Zhuo J, Sun XW et al (2008) Thulium laser versus standard transurethral resection of the prostate: a randomized prospective trial. Eur Urol 53(2):382–389CrossRefPubMed
9.
go back to reference Xia SJ, Zhang YN, Lu J et al (2005) Thulium laser resection of prostate-tangerine technique in treatment of benign prostate hyperplasia. Zhonghua Yi Xue Za Zhi 85(45):3225–3228PubMed Xia SJ, Zhang YN, Lu J et al (2005) Thulium laser resection of prostate-tangerine technique in treatment of benign prostate hyperplasia. Zhonghua Yi Xue Za Zhi 85(45):3225–3228PubMed
10.
go back to reference Gao X, Ren S, Xu C et al (2008) Thulium laser resection via a flexible cystoscope for recurrent non-muscle-invasive bladder cancer: initial clinical experience. BJU Int 102(9):1115–1118CrossRefPubMed Gao X, Ren S, Xu C et al (2008) Thulium laser resection via a flexible cystoscope for recurrent non-muscle-invasive bladder cancer: initial clinical experience. BJU Int 102(9):1115–1118CrossRefPubMed
11.
go back to reference Yang Y, Hong BF, Wei ZT (2008) Continuous wave laser of 2 microm for bladder tumor treatment. Zhonghua Wai Ke Za Zhi 46(18):1410–1412PubMed Yang Y, Hong BF, Wei ZT (2008) Continuous wave laser of 2 microm for bladder tumor treatment. Zhonghua Wai Ke Za Zhi 46(18):1410–1412PubMed
12.
go back to reference Okamura K, Ono Y, Kinukawa T et al (2002) Randomized study of single early instillation of (2”R)-4’-O-tetrahydropyranyl-doxorubicin for a single superficial bladder carcinoma. Cancer 94(9):2363–2368CrossRefPubMed Okamura K, Ono Y, Kinukawa T et al (2002) Randomized study of single early instillation of (2”R)-4’-O-tetrahydropyranyl-doxorubicin for a single superficial bladder carcinoma. Cancer 94(9):2363–2368CrossRefPubMed
13.
go back to reference Böhle A, Leyh H, Frei C et al (2009) Single postoperative instillation of gemcitabine in patients with non-muscle-invasive transitional cell carcinoma of the bladder: a randomised, double-blind, placebo-controlled phase III multicentre study. Eur Urol 56(3):495–503CrossRefPubMed Böhle A, Leyh H, Frei C et al (2009) Single postoperative instillation of gemcitabine in patients with non-muscle-invasive transitional cell carcinoma of the bladder: a randomised, double-blind, placebo-controlled phase III multicentre study. Eur Urol 56(3):495–503CrossRefPubMed
14.
go back to reference Syed HA, Biyani CS, Bryan N et al (2001) Holmium:YAG laser treatment of recurrent superficial bladder carcinoma: initial clinical experience. J Endourol 15(6):625–627CrossRefPubMed Syed HA, Biyani CS, Bryan N et al (2001) Holmium:YAG laser treatment of recurrent superficial bladder carcinoma: initial clinical experience. J Endourol 15(6):625–627CrossRefPubMed
15.
go back to reference Xishuang S, Deyong Y, Xiangyu C et al (2010) Comparing the safety and efficiency of conventional monopolar, plasmakinetic, and holmium laser transurethral resection of primary non-muscle invasive bladder cancer. J Endourol 24(1):69–73CrossRefPubMed Xishuang S, Deyong Y, Xiangyu C et al (2010) Comparing the safety and efficiency of conventional monopolar, plasmakinetic, and holmium laser transurethral resection of primary non-muscle invasive bladder cancer. J Endourol 24(1):69–73CrossRefPubMed
16.
go back to reference Zhu Y, Jiang X, Zhang J et al (2008) Safety and efficacy of holmium laser resection for primary nonmuscle-invasive bladder cancer versus transurethral electroresection: single-center experience. Urology 72(3):608–612CrossRefPubMed Zhu Y, Jiang X, Zhang J et al (2008) Safety and efficacy of holmium laser resection for primary nonmuscle-invasive bladder cancer versus transurethral electroresection: single-center experience. Urology 72(3):608–612CrossRefPubMed
17.
18.
go back to reference Marks AJ, Teichman JM (2007) Lasers in clinical urology: state of the art and new horizons. World J Urol 25(3):227–233CrossRefPubMed Marks AJ, Teichman JM (2007) Lasers in clinical urology: state of the art and new horizons. World J Urol 25(3):227–233CrossRefPubMed
19.
go back to reference Smith JA (1989) Current concepts in laser treatment of bladder cancer [J]. Prog Clin Biol Res 303:463–469PubMed Smith JA (1989) Current concepts in laser treatment of bladder cancer [J]. Prog Clin Biol Res 303:463–469PubMed
Metadata
Title
Clinical observation on 2 micron laser for non-muscle-invasive bladder tumor treatment: single-center experience
Authors
Chen Zhong
Sanwei Guo
Yueqing Tang
Shujie Xia
Publication date
01-04-2010
Publisher
Springer-Verlag
Published in
World Journal of Urology / Issue 2/2010
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI
https://doi.org/10.1007/s00345-010-0532-8

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