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European Radiology

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01-05-2018 | Magnetic Resonance

Feasibility of free-breathing dynamic contrast-enhanced MRI of gastric cancer using a golden-angle radial stack-of-stars VIBE sequence: comparison with the conventional contrast-enhanced breath-hold 3D VIBE sequence

Authors: Huan-Huan Li, Hui Zhu, Lei Yue, Yi Fu, Robert Grimm, Alto Stemmer, Cai-Xia Fu, Wei-jun Peng

Published in: European Radiology | Issue 5/2018

Abstract

Objectives

To investigate the feasibility and diagnostic value of free-breathing, radial, stack-of-stars three-dimensional (3D) gradient echo (GRE) sequence (“golden angle”) on dynamic contrast-enhanced (DCE) MRI of gastric cancer.

Methods

Forty-three gastric cancer patients were divided into cooperative and uncooperative groups. Respiratory fluctuation was observed using an abdominal respiratory gating sensor. Those who breath-held for more than 15 s were placed in the cooperative group and the remainder in the uncooperative group. The 3-T MRI scanning protocol included 3D GRE and conventional breath-hold VIBE (volume-interpolated breath-hold examination) sequences, comparing images quantitatively and qualitatively. DCE-MRI parameters from VIBE images of normal gastric wall and malignant lesions were compared.

Results

For uncooperative patients, 3D GRE scored higher qualitatively, and had higher SNRs (signal-to-noise ratios) and CNRs (contrast-to-noise ratios) than conventional VIBE quantitatively. Though 3D GRE images scored lower in qualitative parameters compared with conventional VIBE for cooperative patients, it provided images with fewer artefacts. DCE parameters differed significantly between normal gastric wall and lesions, with higher Ve (extracellular volume) and lower Kep (reflux constant) in gastric cancer.

Conclusions

The free-breathing, golden-angle, radial stack-of-stars 3D GRE technique is feasible for DCE-MRI of gastric cancer. Dynamic enhanced images can be used for quantitative analysis of this malignancy.

Key Points

• Golden-angle radial stack-of-stars VIBE aids gastric cancer MRI diagnosis.

• The 3D GRE technique is suitable for patients unable to suspend respiration.

• Method scored higher in the qualitative evaluation for uncooperative patients.

• The technique produced images with fewer artefacts than conventional VIBE sequence.

• Dynamic enhanced images can be used for quantitative analysis of gastric cancer.

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Title: Feasibility of free-breathing dynamic contrast-enhanced MRI of gastric cancer using a golden-angle radial stack-of-stars VIBE sequence: comparison with the conventional contrast-enhanced breath-hold 3D VIBE sequence
Authors: Huan-Huan Li
Hui Zhu
Lei Yue
Yi Fu
Robert Grimm
Alto Stemmer
Cai-Xia Fu
Wei-jun Peng
Publication date: 01-05-2018
Publisher: Springer Berlin Heidelberg
Published in: European Radiology / Issue 5/2018
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-017-5193-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Feasibility of free-breathing dynamic contrast-enhanced MRI of gastric cancer using a golden-angle radial stack-of-stars VIBE sequence: comparison with the conventional contrast-enhanced breath-hold 3D VIBE sequence

Abstract

Objectives

Methods

Results

Conclusions

Key Points

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusions

Key Points

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