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01-04-2017 | Computed Tomography

Three-dimensional maximum principal strain using cardiac computed tomography for identification of myocardial infarction

Authors: Yuki Tanabe, Teruhito Kido, Akira Kurata, Shun Sawada, Hiroshi Suekuni, Tomoyuki Kido, Takahiro Yokoi, Teruyoshi Uetani, Katsuji Inoue, Masao Miyagawa, Teruhito Mochizuki

Published in: European Radiology | Issue 4/2017

Abstract

Objectives

To evaluate the feasibility of three-dimensional (3D) maximum principal strain (MP-strain) derived from cardiac computed tomography (CT) for detecting myocardial infarction (MI).

Methods

Forty-three patients who underwent cardiac CT and magnetic resonance imaging (MRI) were retrospectively selected. Using the voxel tracking of motion coherence algorithm, the peak CT MP-strain was measured using the 16-segment model. With the trans-mural extent of late gadolinium enhancement (LGE) and the distance from MI, all segments were classified into four groups (infarcted, border, adjacent, and remote segments); infarcted and border segments were defined as MI with LGE positive. Diagnostic performance of MP-strain for detecting MI was compared with per cent systolic wall thickening (%SWT) assessed by MRI using receiver-operating characteristic curve analysis at a segment level.

Results

Of 672 segments excluding16 segments influenced by artefacts, 193 were diagnosed as MI. Sensitivity and specificity of peak MP-strain to identify MI were 81 % [95 % confidence interval (95 % CI): 74-88 %] and 86 % (81-92 %) compared with %SWT: 76 % (60-95 %) and 68 % (48-84 %), respectively. The area under the curve of peak MP-strain was superior to %SWT [0.90 (0.87-0.93) vs. 0.80 (0.76-0.83), p < 0.05].

Conclusions

CT MP-strain has a potential to provide incremental value to coronary CT angiography for detecting MI.

Key Points

• CT MP-strain allows for three-dimensional assessment of regional cardiac function.

• CT-MP strain has high diagnostic accuracy for detecting myocardial infarction.

• CT-MP strain may assist in tissue characterisation of myocardium assessed by LGE-MRI.

• CT-MP strain provides incremental values to coronary CTA for detecting myocardial infarction.

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Title: Three-dimensional maximum principal strain using cardiac computed tomography for identification of myocardial infarction
Authors: Yuki Tanabe
Teruhito Kido
Akira Kurata
Shun Sawada
Hiroshi Suekuni
Tomoyuki Kido
Takahiro Yokoi
Teruyoshi Uetani
Katsuji Inoue
Masao Miyagawa
Teruhito Mochizuki
Publication date: 01-04-2017
Publisher: Springer Berlin Heidelberg
Published in: European Radiology / Issue 4/2017
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-016-4550-9

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Springer Medicine

Three-dimensional maximum principal strain using cardiac computed tomography for identification of myocardial infarction

Abstract

Objectives

Methods

Results

Conclusions

Key Points

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusions

Key Points

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