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European Radiology
Published in: European Radiology 1/2017

01-01-2017 | Head and Neck

The diagnostic performance of shear wave elastography for malignant cervical lymph nodes: A systematic review and meta-analysis

Authors: Chong Hyun Suh, Young Jun Choi, Jung Hwan Baek, Jeong Hyun Lee

Published in: European Radiology | Issue 1/2017

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Abstract

Objective

To evaluate the diagnostic performance of shear wave elastography for malignant cervical lymph nodes.

Methods

We searched the Ovid-MEDLINE and EMBASE databases for published studies regarding the use of shear wave elastography for diagnosing malignant cervical lymph nodes. The diagnostic performance of shear wave elastography was assessed using bivariate modelling and hierarchical summary receiver operating characteristic modelling. Meta-regression analysis and subgroup analysis according to acoustic radiation force impulse imaging (ARFI) and Supersonic shear imaging (SSI) were also performed.

Results

Eight eligible studies which included a total sample size of 481 patients with 647 cervical lymph nodes, were included. Shear wave elastography showed a summary sensitivity of 81 % (95 % CI: 72–88 %) and specificity of 85 % (95 % CI: 70–93 %). The results of meta-regression analysis revealed that the prevalence of malignant lymph nodes was a significant factor affecting study heterogeneity (p < .01). According to the subgroup analysis, the summary estimates of the sensitivity and specificity did not differ between ARFI and SSI (p = .93).

Conclusion

Shear wave elastography is an acceptable imaging modality for diagnosing malignant cervical lymph nodes. We believe that both ARFI and SSI may have a complementary role for diagnosing malignant cervical lymph nodes.

Key Points

• Shear wave elastography is acceptable modality for diagnosing malignant cervical lymph nodes.
• Shear wave elastography demonstrated summary sensitivity of 81 % and specificity of 85 %.
• ARFI and SSI have complementary roles for diagnosing malignant cervical lymph nodes.
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Metadata
Title
The diagnostic performance of shear wave elastography for malignant cervical lymph nodes: A systematic review and meta-analysis
Authors
Chong Hyun Suh
Young Jun Choi
Jung Hwan Baek
Jeong Hyun Lee
Publication date
01-01-2017
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 1/2017
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-016-4378-3

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