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Published in: European Radiology 1/2017

Open Access 01-01-2017 | Gastrointestinal

Liver CT for vascular mapping during radioembolisation workup: comparison of an early and late arterial phase protocol

Authors: Andor F. van den Hoven, Manon N. G. J. A. Braat, Jip F. Prince, Pieter J. van Doormaal, Maarten S. van Leeuwen, Marnix G. E. H. Lam, Maurice A. A. J. van den Bosch

Published in: European Radiology | Issue 1/2017

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Abstract

Objectives

To compare right gastric (RGA) and segment 4 artery (A4) origin detection rates during radioembolisation workup between early and late arterial phase liver CT protocols.

Methods

100 consecutive patients who underwent liver CT between May 2012–January 2015 with early or late arterial phase protocol (n = 50 each, 10- vs. 20-s post-threshold delay) were included. RGA/A4 origin detection rates, assessed by two raters, and contrast-to-noise ratio (CNR) of the hepatic artery relative to the portal vein were compared between the protocols.

Results

The first–second rater scored the RGA origin as visible in 58–65 % (specific proportion of agreement 82 %, κ = 0.62); A4 origin in 96–89 % (94 %, κ = 0.54). Thirty-six percent of RGA origins not detectable by DSA were identified on CT. Origin detection rates were not significantly different for early/late arterial phases. Mean CNR was higher in the early arterial phase protocol (1.7 vs. 1.2, p < 0.001).

Conclusion

A 10-s delay arterial phase CT protocol does not significantly improve detection of small intra- and extrahepatic branches. RGA origin detection requires further optimization, whereas A4/MHA origin detection is adequate, with good inter-rater reproducibility. CT remains important for preprocedural planning, because it may reveal arterial anatomy not discernible on DSA.

Key Points

An early arterial phase does not significantly improve RGA and A4/MHA origin detection.
RGA origin detection (5865 %) on CT is still suboptimal.
36 % of RGA origins undetectable on DSA can be identified on CT.
A4/MHA origin detection (8996 %) on CT is excellent.
Inter-rater reproducibility is good for RGA and A4/MHA origin detection on CT.
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Metadata
Title
Liver CT for vascular mapping during radioembolisation workup: comparison of an early and late arterial phase protocol
Authors
Andor F. van den Hoven
Manon N. G. J. A. Braat
Jip F. Prince
Pieter J. van Doormaal
Maarten S. van Leeuwen
Marnix G. E. H. Lam
Maurice A. A. J. van den Bosch
Publication date
01-01-2017
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 1/2017
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-016-4343-1

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