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01-10-2016 | Interventional

Can prostatic arterial embolisation (PAE) reduce the volume of the peripheral zone? MRI evaluation of zonal anatomy and infarction after PAE

Authors: Yen-Ting Lin, Grégory Amouyal, Jean-Michel Correas, Héléna Pereira, Olivier Pellerin, Costantino Del Giudice, Carole Déan, Nicolas Thiounn, Marc Sapoval

Published in: European Radiology | Issue 10/2016

Abstract

Objectives

To assess the impact of prostatic arterial embolisation (PAE) on various prostate gland anatomical zones.

Methods

We retrospectively reviewed paired MRI scans obtained before and after PAE for 25 patients and evaluated changes in volumes of the median lobe (ML), central gland (CG), peripheral zone (PZ) and whole prostate gland (WPV) following PAE. We used manual segmentation to calculate volume on axial view T2-weighted images for ML, CG and WPV. We calculated PZ volume by subtracting CG volume from WPV. Enhanced phase on dynamic contrasted-enhanced MRI was used to evaluate the infarction areas after PAE. Clinical results of International Prostate Symptom Score and International Index of Erectile Function questionnaires and the urodynamic study were evaluated before and after PAE.

Results

Significant reductions in volume were observed after PAE for ML (26.2 % decrease), CG (18.8 %), PZ (16.4 %) and WPV (19.1 %; p < 0.001 for all these volumes). Patients with clinical failure had smaller volume reductions for WPV, ML and CG (all p < 0.05). Patients with significant CG infarction after PAE displayed larger WPV, ML and CG volume reductions (all p < 0.01).

Conclusions

PAE can significantly decrease WPV, ML, CG and PZ volumes, and poor clinical outcomes are associated with smaller volume reductions.

Key Points

• The MRI segmentation method provides detailed comparisons of prostate volume change.

• Prostatic arterial embolisation (PAE) decreased central gland and peripheral zone volumes.

• Prostates with infarction after PAE showed larger decreases in volume.

• A larger decrease in prostate volume is associated with clinical success.

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Title: Can prostatic arterial embolisation (PAE) reduce the volume of the peripheral zone? MRI evaluation of zonal anatomy and infarction after PAE
Authors: Yen-Ting Lin
Grégory Amouyal
Jean-Michel Correas
Héléna Pereira
Olivier Pellerin
Costantino Del Giudice
Carole Déan
Nicolas Thiounn
Marc Sapoval
Publication date: 01-10-2016
Publisher: Springer Berlin Heidelberg
Published in: European Radiology / Issue 10/2016
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-015-4177-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Can prostatic arterial embolisation (PAE) reduce the volume of the peripheral zone? MRI evaluation of zonal anatomy and infarction after PAE

Abstract

Objectives

Methods

Results

Conclusions

Key Points

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusions

Key Points

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