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European Radiology
Published in: European Radiology 10/2016

01-10-2016 | Magnetic Resonance

Diffusion measurement of intraplaque hemorrhage and intramural hematoma using diffusion weighted MRI at 3T in cervical artery

Authors: Bin Yao, Li Yang, Guangbin Wang, Honglu Shi, Shanshan Wang, Huihua Li, Weibo Chen, Queenie Chan

Published in: European Radiology | Issue 10/2016

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Abstract

Objectives

To assess the difference between carotid haemorrhagic plaque and non-haemorrhagic plaque by using diffusion-weighted imaging (DWI) and to evaluate carotid intraplaque haemorrhage (IPH) and intramural hematoma (IMH) of cervical artery dissection with apparent diffusion coefficient (ADC) measurement.

Methods

Fifty-one symptomatic patients underwent 3.0-T carotid MR imaging, including conventional sequences, three-dimensional (3D) magnetization-prepared rapid acquisition gradient-echo (MPRAGE) sequence, and DWI. Thirty-nine patients with carotid plaque and eight patients with IMH of cervical artery dissection were finally included. The groups of hemorrhagic plaque, non-hemorrhagic plaque and IMH were divided according to 3D MPRAGE sequence. ADC values of different groups were measured, and t tests were performed.

Results

The mean ADC values of hemorrhagic plaques, non-hemorrhagic plaque and IMH were (1.284 ± 0.327) × 10-3mm2/s, (1.766 ± 0.477) × 10-3mm2/s, and (0.563 ± 0.119) × 10-3mm2/s, respectively. The mean ADC values of hemorrhagic and non-hemorrhagic regions in the hemorrhagic plaque group were (0.985 ± 0.376) × 10-3mm2/s and (1.480 ± 0.465) × 10-3mm2/s, respectively. The differences between the hemorrhagic plaque and non-hemorrhagic plaque, hemorrhagic region and non-hemorrhagic region in hemorrhagic plaque, and the hemorrhagic region in the hemorrhagic plaque and IMH of artery dissection were significant (P < 0.05).

Conclusion

DWI may be a useful complement to conventional MR imaging for identifying haemorrhage of carotid plaques and differentiate IMHs from IPH.

Key Points

• ADC values of IPH are lower than the plaque without IPH.
• DWI might be a useful complement to identify IPH.
• IMH may be differentiated from IPH by using DWI.
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Metadata
Title
Diffusion measurement of intraplaque hemorrhage and intramural hematoma using diffusion weighted MRI at 3T in cervical artery
Authors
Bin Yao
Li Yang
Guangbin Wang
Honglu Shi
Shanshan Wang
Huihua Li
Weibo Chen
Queenie Chan
Publication date
01-10-2016
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 10/2016
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-015-4149-6

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