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Published in: European Radiology 11/2014

01-11-2014 | Vascular-Interventional

Ultrafast cone-beam computed tomography imaging and postprocessing data during image-guided therapeutic practice

Authors: Jijo Paul, Emmanuel C. Mbalisike, Thomas J. Vogl

Published in: European Radiology | Issue 11/2014

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Abstract

Objective

Our objective was to evaluate ultrafast cone-beam computed tomography (u-CBCT) image data using cross-sectional images, perfusion blood volume (PBV), and image fusion during tumour detection at the course of transarterial chemoembolization.

Methods

One hundred and fifty patients (63 ± 20 years; 33–82) were examined from February to October 2013 with u-CBCT. Tumour delineation and conspicuity were determined using u-CBCT cross-sectional PBV and u-CBCT-magnetic resonance imaging (MRI) fused data sets for hyperenhanced (HYET), heterogeneously enhanced (HEET), and unenhanced (UET) tumour categories. Catheter localisation and tumour feeding vessels were assessed using all data sets. Quantitative and qualitative analyses were performed using appropriate statistical tests.

Result

Qualitative and quantitative tumour delineation showed significant difference (all P < 0.05) among tumour categories. Mean tumour–liver–contrast was higher in HYET than in HEET, and UET; moreover, differences between tumour categories were statistically significant (all P < 0.0001). Fused data showed higher value with statistical significance (P < 0.05) compared with other data sets during catheter localisation and feeding-vessel identification.

Conclusion

Tumour delineation was clearly possible using u-CBCT cross sections with contrast material. PBV uses color-coded images to increase detection and produces good tumour differentiation. Image fusion helps accurately identify tumour and feeding vessels and locate contrast material injection sites and catheter tips without additional data acquisition.

Key points

Ultrafast CBCT cross-sectional data provide good tumour delineation with contrast material
Postprocessed PBV using u-CBCT increased detectability and tumour differentiation
u-CBCT cross-sectional PBV and u-CBCT-MRI data helps image guidance during chemoembolization
u-CBCT-MRI can identify tumours and feeding vessels and locate catheter tip accurately
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Metadata
Title
Ultrafast cone-beam computed tomography imaging and postprocessing data during image-guided therapeutic practice
Authors
Jijo Paul
Emmanuel C. Mbalisike
Thomas J. Vogl
Publication date
01-11-2014
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 11/2014
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-014-3321-8

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