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European Radiology

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01-01-2014 | Head and Neck

Head and neck tumours: combined MRI assessment based on IVIM and TIC analyses for the differentiation of tumors of different histological types

Authors: Misa Sumi, Takashi Nakamura

Published in: European Radiology | Issue 1/2014

Abstract

Objectives

We evaluated the combined use of intravoxel incoherent motion (IVIM) and time-signal intensity curve (TIC) analyses to diagnose head and neck tumours.

Methods

We compared perfusion-related parameters (PP) and molecular diffusion values (D) determined from IVIM theory and TIC profiles among 92 tumours with different histologies.

Results

IVIM parameters (f and D values) and TIC profiles in combination were distinct among the different types of head and neck tumours, including squamous cell carcinomas (SCCs), lymphomas, malignant salivary gland tumours, Warthin’s tumours, pleomorphic adenomas and schwannomas. A multiparametric approach using both IVIM parameters and TIC profiles differentiated between benign and malignant tumours with 97 % accuracy and diagnosed different tumour types with 89 % accuracy.

Conclusions

Combined use of IVIM parameters and TIC profiles has high efficacy in diagnosing head and neck tumours.

Key points

• Head and neck tumours have wide MR perfusion/diffusion properties.

• Dynamic contrast-enhanced (DCE) MR imaging can characterise tumour perfusion (TIC analysis).

• Intravoxel incoherent motion (IVIM) imaging can provide diffusion and perfusion properties.

• However, IVIM or DCE imaging alone is insufficient for diagnosing head/neck tumours.

• Multiparametric approach using both IVIM and TIC profiles can facilitate the diagnosis.

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Title: Head and neck tumours: combined MRI assessment based on IVIM and TIC analyses for the differentiation of tumors of different histological types
Authors: Misa Sumi
Takashi Nakamura
Publication date: 01-01-2014
Publisher: Springer Berlin Heidelberg
Published in: European Radiology / Issue 1/2014
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-013-3002-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Head and neck tumours: combined MRI assessment based on IVIM and TIC analyses for the differentiation of tumors of different histological types

Abstract

Objectives

Methods

Results

Conclusions

Key points

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusions

Key points

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