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01-05-2013 | Magnetic Resonance

Free-breathing dynamic contrast-enhanced MRI of the abdomen and chest using a radial gradient echo sequence with K-space weighted image contrast (KWIC)

Authors: Kyung Won Kim, Jeong Min Lee, Yong Sik Jeon, Sung Eun Kang, Jee Hyun Baek, Joon Koo Han, Byung Ihn Choi, Yung-Jue Bang, Berthold Kiefer, Kai Tobias Block, Hyunjun Ji, Simon Bauer, Chin Kim

Published in: European Radiology | Issue 5/2013

Abstract

Objectives

To evaluate the feasibility of free-breathing, dynamic contrast-enhanced (DCE) MRI of the abdomen and thorax using the radial-gradient-echo sequence with k-space weighted image contrast (KWIC) reconstruction.

Methods

Institutional review board approval was obtained. Fourteen patients underwent free-breathing radial DCE-MRI. Radial MRI yielded full-frame images by gridding all k-space data and time-resolved subframe images by using KWIC reconstruction technique. Using subframe KWIC images, voxel-wise perfusion maps were created. For comparison, the breath-hold conventional Cartesian 3D-gradient-echo sequence (VIBE) was also performed during the equilibrium phase. The image qualities of radial and conventional VIBE images were compared quantitatively and qualitatively.

Results

Radial DCE-MRI provided high spatial resolution (1.4 × 1.4 mm) and temporal resolution (4.1 s for subframe images) allowing voxel-wise perfusion mapping with negligible motion or streaking artefacts. There were no significant differences in SNR between full-frame radial images and conventional VIBE images (79.08 vs 74.80, P > 0.05). Overall image quality score of full-frame radial images was slightly lower than that of conventional VIBE images (3.88 ± 0.59 vs. 4.31 ± 0.97, P < 0.05), but provided clinically useful images.

Conclusions

The free-breathing radial DCE-MRI can provide high spatial and temporal resolution while maintaining reasonably high image quality and thus is a feasible technique for DCE-MRI in the abdomen and thorax.

Key Points

• Dynamic contrast-enhanced magnetic resonance imaging (DCE) MRI is important in oncological imaging

• Radial MRI with k-space weighted image contrast (KWIC) reconstruction offers potential improvements

• Radial DCE-MRI provides good image quality, reduced artefacts and high spatial/temporal resolution

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Title: Free-breathing dynamic contrast-enhanced MRI of the abdomen and chest using a radial gradient echo sequence with K-space weighted image contrast (KWIC)
Authors: Kyung Won Kim
Jeong Min Lee
Yong Sik Jeon
Sung Eun Kang
Jee Hyun Baek
Joon Koo Han
Byung Ihn Choi
Yung-Jue Bang
Berthold Kiefer
Kai Tobias Block
Hyunjun Ji
Simon Bauer
Chin Kim
Publication date: 01-05-2013
Publisher: Springer-Verlag
Published in: European Radiology / Issue 5/2013
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-012-2699-4

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Free-breathing dynamic contrast-enhanced MRI of the abdomen and chest using a radial gradient echo sequence with K-space weighted image contrast (KWIC)

Abstract

Objectives

Methods

Results

Conclusions

Key Points

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusions

Key Points

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