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01-04-2012 | Interventional

Diagnostic accuracy of C-arm CT during selective transcatheter angiography for hepatocellular carcinoma: comparison with intravenous contrast-enhanced, biphasic, dynamic MDCT

Authors: Hiroki Higashihara, Keigo Osuga, Hiromitsu Onishi, Atsushi Nakamoto, Takahiro Tsuboyama, Noboru Maeda, Masatoshi Hori, Tonsok Kim, Noriyuki Tomiyama

Published in: European Radiology | Issue 4/2012

Abstract

Purpose

This study was aimed to compare the accuracy, sensitivity, and positive predictive value of C-arm CT (CACT) during selective transcatheter angiography with those of multidetector CT (MDCT) in the detection of hepatocellular carcinoma (HCC).

Material and methods

In this prospective study, 30 patients (mean age, 73 years) with unresectable HCC were examined with CACT before chemoembolisation. Images of a combination of CACT during arterial portography (CACTAP) and dual-phase CACT during hepatic arteriography (CACTHA) was obtained and images of intravenous contrast-enhanced, biphasic, dynamic, MDCT was also obtained beforehand. Three blinded observers independently reviewed CACT and MDCT. Diagnostic accuracy was evaluated by the alternative free-response receiver operating characteristic (AFROC) method. Sensitivities and positive predictive values (PPV) were analyzed with the paired t-test.

Results

In the mean area under the AFROC curve (Az), there was no significant difference between MDCT and CACT (MDCT, mean Az value, 0.83; CACT, 0.85, respectively) (P = 0.32). There was also no significant difference between the two techniques in sensitivity (MDCT, mean 0.65; CACT, 0.60) and PPV (MDCT, mean 0.98; CACT, 0.97) (P = 0.40, P = 0.68, respectively).

Conclusion

The diagnostic accuracy of CACT was equivalent to that of biphasic CT in the diagnosis of HCC.

Key Points

C-arm CT helps detection of hepatocellular carcinoma (HCC) during interventional (TACE) treatment.
C-arm CT for HCC seemed just as accurate as biphasic CT.
TACE can be performed with greater confidence using C-arm CT.

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Title: Diagnostic accuracy of C-arm CT during selective transcatheter angiography for hepatocellular carcinoma: comparison with intravenous contrast-enhanced, biphasic, dynamic MDCT
Authors: Hiroki Higashihara
Keigo Osuga
Hiromitsu Onishi
Atsushi Nakamoto
Takahiro Tsuboyama
Noboru Maeda
Masatoshi Hori
Tonsok Kim
Noriyuki Tomiyama
Publication date: 01-04-2012
Publisher: Springer-Verlag
Published in: European Radiology / Issue 4/2012
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-011-2324-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Diagnostic accuracy of C-arm CT during selective transcatheter angiography for hepatocellular carcinoma: comparison with intravenous contrast-enhanced, biphasic, dynamic MDCT

Abstract

Purpose

Material and methods

Results

Conclusion

Key Points

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Material and methods

Results

Conclusion

Key Points

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