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European Radiology

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01-08-2011 | Magnetic Resonance

4D-MR flow analysis in patients after repair for tetralogy of Fallot

Authors: J. Geiger, M. Markl, B. Jung, J. Grohmann, B. Stiller, M. Langer, R. Arnold

Published in: European Radiology | Issue 8/2011

Abstract

Objectives

Comprehensive analysis of haemodynamics by 3D flow visualisation and retrospective flow quantification in patients after repair of tetralogy of Fallot (TOF).

Methods

Time-resolved flow-sensitive 4D MRI (spatial resolution ~ 2.5 mm, temporal resolution = 38.4 ms) was acquired in ten patients after repair of TOF and in four healthy controls. Data analysis included the evaluation of haemodynamics in the aorta, the pulmonary trunk (TP) and left (lPA) and right (rPA) pulmonary arteries by 3D blood flow visualisation using particle traces, and quantitative measurements of flow velocity.

Results

3D visualisation of whole heart haemodynamics provided a comprehensive overview on flow pattern changes in TOF patients, mainly alterations in flow velocity, retrograde flow and pathological vortices. There was consistently higher blood flow in the rPA of the patients (rPA/lPA flow ratio: 2.6 ± 2.5 vs. 1.1 ± 0.1 in controls). Systolic peak velocity in the TP was higher in patients (1.9 m/s ± 0.7 m/s) than controls (0.9 m/s ± 0.1 m/s).

Conclusions

4D flow-sensitive MRI permits the comprehensive evaluation of blood flow characteristics in patients after repair of TOF. Altered flow patterns for different surgical techniques in the small patient cohort may indicate its value for patient monitoring and potentially identifying optimal surgical strategies.

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Title: 4D-MR flow analysis in patients after repair for tetralogy of Fallot
Authors: J. Geiger
M. Markl
B. Jung
J. Grohmann
B. Stiller
M. Langer
R. Arnold
Publication date: 01-08-2011
Publisher: Springer-Verlag
Published in: European Radiology / Issue 8/2011
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-011-2108-4

Keynote webinar | Spotlight on medication adherence

Springer Medicine

4D-MR flow analysis in patients after repair for tetralogy of Fallot

Abstract

Objectives

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusions

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